The field of regenerative medicine, particularly in the context of muscle regeneration following exercise-induced lesions, is a rapidly advancing area of research. Intense or prolonged physical activity often leads to muscle damage, manifesting as exercise-induced lesions that require effective repair mechanisms. The body's response involves a sophisticated network of regenerative pathways, where stem cells and growth factors play crucial roles in facilitating healing and recovery. Recent studies have highlighted the importance of these biological entities in muscle repair, yet the precise mechanisms through which they operate remain incompletely understood. Despite significant progress, there are still gaps in our knowledge regarding the interaction and regulation of these pathways, as well as the potential for therapeutic interventions. Addressing these gaps is essential for advancing our understanding and developing innovative treatments for muscle injuries and degenerative disorders.
This research topic aims to explore the intricate processes involved in muscle regeneration following exercise-induced lesions, with a particular focus on the roles of stem cells and growth factors. The primary objective is to investigate how these elements contribute to the regeneration process, examining their functionality and interactions within the regenerative pathways. By delving into these dynamics, the research seeks to uncover new insights that could lead to breakthroughs in regenerative medicine, ultimately enhancing therapeutic strategies for muscle repair and recovery.
To gather further insights in the realm of muscle regeneration and the role of stem cells and growth factors, we welcome articles addressing, but not limited to, the following themes:
- Exercise-induced skeletal muscle injury and regeneration
- Therapeutic strategies to accelerate force recovery following injury
- Novel molecular mechanisms implicated in skeletal muscle regeneration
- Crosstalk among biological processes or signaling pathways related to skeletal muscle regeneration
- The role of leukocytes in skeletal muscle regeneration
- The role of hormones in skeletal muscle regeneration
- Crosstalk between stem cells and growth factors, identifying key mediators and regulatory networks
- The role of the extracellular matrix and microenvironment in modulating the effects of stem cells and growth factors on muscle regeneration
- Impact of physical exercise on stem cells and growth factors in muscle regeneration
Keywords: regenerative medicine, exercise, stem cells, lesion, injury, recovery, muscle, regeneration
Important note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.
