Key Topics in Integrative Physiology - Consolidating Whole-Body Physiology Using Cutting-Edge Knowledge

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About this Research Topic

Submission deadlines

  1. Manuscript Submission Deadline 30 December 2025

  2. This Research Topic is currently accepting articles.

Background

Integrative physiology uses a holistic approach to determine how (and why) different systems interact within the body and function together to maintain homeostasis. It consolidates insights from multiple levels, from the molecule to the entire body, to provide a comprehensive understanding of physiological processes. Leveraging cutting-edge technologies, such as advanced imaging, omics (genomics, proteomics, metabolomics), computational modeling, and artificial intelligence, helps to bridge the gaps between separated physiological studies and the complex, interconnected nature of whole-body function. This approach is crucial for unraveling the fundamental principles governing human body physiology in health and disease, always mindful of the intricate interplay between organs and systems. Therefore, integrative physiology research provides a unified view of how various physiological processes are coordinated and regulated within the body, enhancing our ability to address multifaceted health challenges critical in personalized healthcare.

This Research Topic welcomes contributions that improves our understanding about processes and mechanisms in current and emerging themes of human physiology. Our primary focus is human body functions in a highly complex, although subtle as harmonious, unit. Data from human subjects will be prioritized. Potential areas of interest include, but are not limited to
- Integrative physiology
- Locomotion / Exercise / Muscle / Performance enhancement
- Active living and well-being
- Nutritional physiology
- Cardiovascular physiology
- Respiratory physiology
- Renal urinary physiology and water-electrolyte and metabolic balance
- Gastrointestinal physiology
- Endocrine, reproduction and developmental physiology
- Human aging
- Nervous system physiology
- Immune system physiology
- Comparative physiology

We welcome the submission of different article types to this collection, including reviews, mini-reviews, short-papers and full original research papers.

For a complete list of article types that can be considered, please follow this link.

We encourage all interested researchers to submit an abstract to any of the guest editors before submitting their manuscript.

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Article types and fees

This Research Topic accepts the following article types, unless otherwise specified in the Research Topic description:

  • Brief Research Report
  • Case Report
  • Clinical Trial
  • Conceptual Analysis
  • Data Report
  • Editorial
  • FAIR² Data
  • FAIR² DATA Direct Submission
  • General Commentary

Articles that are accepted for publication by our external editors following rigorous peer review incur a publishing fee charged to Authors, institutions, or funders.

Keywords: integrative physiology, whole-body physiology

Important note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.

Topic editors

Manuscripts can be submitted to this Research Topic via the main journal or any other participating journal.

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