Chemical Biology and Coordination Chemistry

Coordination chemistry is important in many systems in Chemical Biology and several areas were described at the 45th International Conference on Coordination Chemistry (ICCC45), hosted at Colorado State University. It was held from July 28 to August 3, 2024, in the USA for the first time in 39 years. This is the longest-running international chemistry conference in the world, with a history dating back to 1950. This successful gathering featured distinguished speakers from 37 countries across 6 continents and participants from 44 countries. This conference underscores the global importance of all areas of coordination chemistry and part of the conference was dedicated to advancing chemical biology and biomedical sciences. This Research Topic solicits contributions from conference participants and also welcomes other coordination chemists whose work is relevant to the field of chemical biology.

Coordination chemistry is crucial in bridging the gap between chemistry and biology, providing insights into molecular interactions, enzymatic functions, and therapeutic developments. This area of research has proven essential in understanding biological processes and developing new materials and drugs. The ongoing evolution in coordination chemistry offers potential breakthroughs in addressing challenges faced within biological and biomedical systems.

This Research Topic aims to explore recent advancements in coordination chemistry and its application in chemical biology, particularly focusing on innovations in biomedical systems. We aim to highlight how coordination chemistry can contribute to understanding complex biological mechanisms, assist in the design of novel therapeutic agents, and address pressing health issues. Contributions that explore theoretical and experimental approaches, novel compounds, and their potential applications in improving human health are particularly encouraged.

We welcome original research articles, brief research reports, comprehensive reviews, mini-reviews, perspectives and methodological papers that explore, but are not limited, to the following themes:

o Applications of coordination chemistry in understanding enzymatic mechanisms, metal ion homeostasis, and organelle functions.
o The role of coordination chemistry in the design and synthesis of new therapeutic agents and materials relevant to chemical biology.
o Innovations in analytical techniques related to coordination chemistry for studying biological systems.
o Coordination compounds in drug delivery systems and their potential therapeutic uses.
o Theoretical modelling and structure prediction in coordination chemistry for biological and biomedical applications.

For a full description of each article type, please see here

Keywords: Coordination Chemistry, Chemical Biology, Biomedical Sciences, Molecular Interactions, Enzymatic Functions, Biological Processes

Important note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.