Frontiers in Chemical Biology

Original Research

Published on 20 Nov 2025

Copper complexes containing o-phenylenediamine-based pentadentate ligands catalyze TEMPO-mediated alcohol oxidation

in Structure, Spectroscopy & Imaging

Yuji Mikata
Miyu Akedo
Yutaka Ohsedo
Sunao Shoji
Takashi Matsuo
Attawit Jehdaramarn
Preeyanuch Sangtrirutnugul
Yasuhiro Funahashi

Frontiers in Chemical Biology

doi 10.3389/fchbi.2025.1688400

273 views

Specialty Grand Challenge

Accepted on 30 Oct 2025

Grand challenges in Chemical Biology from the Perspective of Organic Chemical Synthesis

in Organic Chemical Synthesis

Marco Francescato
Hang Liao
Luca Gentilucci

Frontiers in Chemical Biology

540 views

Original Research

Accepted on 30 Oct 2025

Drug repurposing for Chagas disease: Trying to overcome the hit-to-preclinical candidate stage

in Molecular Sciences

Hugo Cerecetto
Claudia Veira
Belén Dávila
Elva Serna
Nilda Portillo
Gloria Yaluff
Guzmán Alvarez
Elena Aguilera

Frontiers in Chemical Biology

141 views

Brief Research Report

Accepted on 27 Oct 2025

An evaluation of high-field asymmetric-waveform ion mobility spectrometry coupled to electron-transfer/higher-energy collision dissociation for ADP-ribosylation proteomics

in Quantitative and Analytical Techniques

Taku Kasai
Gabriel Shlayen
Yuto Nakamura
Masanori Aikawa
Sasha A Singh

Frontiers in Chemical Biology

219 views

Mini Review

Published on 20 Oct 2025

Metals in medicine: unlocking new avenues for neurodegenerative disease treatment

in Bioinorganic Chemistry

Kuan Teng Tan
Kok Whye Cheong
Lai Chun Wong
Hélène C. Bertrand
Nurul Huda Abd Karim
Yie Kie Chong
May Lee Low

Frontiers in Chemical Biology

doi 10.3389/fchbi.2025.1696058

999 views

Original Research

Published on 17 Oct 2025

Quantifying antioxidant activity of hydrophobic compounds using metal-mediated DNA damage

in Bioinorganic Chemistry

Andrea A. E. Gaertner
Nathan R. Perron
Heeren M. G. Anderholm
Daniel C. Whitehead
Julia L. Brumaghim

Frontiers in Chemical Biology

doi 10.3389/fchbi.2025.1677610

467 views

Perspective

Published on 29 Sep 2025

X-ray structures of metal-protein adducts at body temperature: concepts, examples and perspectives

in Bioinorganic Chemistry

Antonello Merlino

Frontiers in Chemical Biology

doi 10.3389/fchbi.2025.1670177

479 views

Correction

Published on 19 Sep 2025

Correction: An activity-based probe for antimicrobial target DXP synthase, a thiamin diphosphate-dependent enzyme

in Molecular Sciences

Lauren B. Coco
Caren L. Freel Meyers

Frontiers in Chemical Biology

doi 10.3389/fchbi.2025.1670585

413 views

Editorial

Published on 19 Sep 2025

Editorial: Linking chemistry to biology and medicine via metal ions: developed from the 16th international symposium on applied bioinorganic chemistry

in Bioinorganic Chemistry

Christina N. Banti
Debbie C. Crans
Ana Maria Da Costa Ferreira
Sotiris K. Hadjikakou

Frontiers in Chemical Biology

doi 10.3389/fchbi.2025.1695257

752 views

Perspective

Published on 04 Sep 2025

Lessons from metals-containing drugs in diagnostic, and theranostic applications for future development of metal-containing non-conventional therapeutics: vanadium compounds for intratumor administration

in Bioinorganic Chemistry

Adam R. Miller
Debbie C. Crans

Frontiers in Chemical Biology

doi 10.3389/fchbi.2025.1639340

1,180 views

Original Research

Published on 14 Aug 2025

Preliminary investigation of Ru(II) complexes bearing nile red chromophores for photodynamic therapy

in Bioinorganic Chemistry

Claire Condon
Oriol Careta-Borràs
Judit Fodor
Amani B. Al Riyami
Xiao Xiao
Jianzhang Zhao
Carme Nogués
Sylvia M. Draper

Frontiers in Chemical Biology

doi 10.3389/fchbi.2025.1620562

1,061 views

Original Research

Published on 12 Aug 2025

Carboxymethyl cellulose hydrogel doped with zinc-aspirinate as a multifunctional material: photoprotection, epithelial regeneration, and biocompatibility

in Bioinorganic Chemistry

Christina N. Banti
Fotakis Lezos
Antonios Hatzidimitriou
Sotiris K. Hadjikakou

Frontiers in Chemical Biology

doi 10.3389/fchbi.2025.1639096

781 views

Editorial

Published on 15 Jul 2025

Editorial: Insights in theoretical modelling, structure prediction and design

in Theoretical Modeling, Structure Prediction & Design

Andrea Ilari
Veronica Morea
Adriana Erica Miele

Frontiers in Chemical Biology

doi 10.3389/fchbi.2025.1653901

820 views

Brief Research Report

Published on 24 Jun 2025

Boronic acid-modified cell-penetrating peptide exhibits superior performance over natural TAT peptide

in Structure, Spectroscopy & Imaging

Pritam Ghosh

Frontiers in Chemical Biology

doi 10.3389/fchbi.2025.1610127

1,767 views
2 citations

Specialty Grand Challenge

Published on 18 Jun 2025

Specialty grand challenges in theoretical modeling, structure prediction and design

in Theoretical Modeling, Structure Prediction & Design

Cécile Exertier
Andrea Ilari

Frontiers in Chemical Biology

doi 10.3389/fchbi.2025.1635423

1,297 views

Original Research

Published on 17 Jun 2025

How vanadium and manganese compounds impact cardiac mitochondrial function

in Bioinorganic Chemistry

Connor C. Dolan
Luke A. Whitcomb
Edgar Del Carpio
Lilliana Rose
Adam J. Chicco
Debbie C. Crans

Frontiers in Chemical Biology

doi 10.3389/fchbi.2025.1602602

1,606 views