Frontiers in Chemical Biology

Brief Research Report

Accepted on 28 May 2025

Boronic Acid-Modified Cell-Penetrating Peptides Exhibit Superior Performance Over Natural TAT Peptide

in Structure, Spectroscopy & Imaging

Pritam Ghosh

Frontiers in Chemical Biology

doi 10.3389/fchbi.2025.1610127

Original Research

Accepted on 16 May 2025

How vanadium and manganese compounds impact cardiac mitochondrial function

in Bioinorganic Chemistry

Connor C Dolan
Luke A Whitcomb
Edgar Del Carpio
Lilliana Rose
Adam Chicco
Debbie C. Crans

Frontiers in Chemical Biology

doi 10.3389/fchbi.2025.1602602

214 views

Original Research

Published on 14 May 2025

Expanding the molecular landscape of fragments binding to trypanothione reductase, a legitimate target for drug design against human African trypanosomiasis

in Theoretical Modeling, Structure Prediction & Design

Cécile Exertier
Lorenzo Antonelli
Vittorio Brufani
Gianni Colotti
Andrea Ilari
Annarita Fiorillo

Frontiers in Chemical Biology

doi 10.3389/fchbi.2025.1605579

471 views

Original Research

Published on 12 May 2025

Exploring the heterodimer MDM2/MDM4 interaction region uncovers high-affinity peptides for therapeutic p53-reactivation

in Theoretical Modeling, Structure Prediction & Design

Marika Attili
Sonia Valentini
Maria Pesavento
Marco Ballarotto
Viviana Scognamiglio
Alfredo Pontecorvi
Antonio Macchiarulo
Fulvio Saccoccia
Fabiola Moretti

Frontiers in Chemical Biology

doi 10.3389/fchbi.2025.1576640

844 views

Original Research

Published on 23 Apr 2025

Structural and dynamical characterization of pRb, LTSV40 and the pRb-LTSV40 complex suggests a common mechanism for pRb inactivation

in Theoretical Modeling, Structure Prediction & Design

Carla Luciana Padilla Franzotti
Nicolas Palopoli
Juliana Palma
Gustavo Pierdominici-Sottile

Frontiers in Chemical Biology

doi 10.3389/fchbi.2025.1538350

634 views

Editorial

Published on 03 Apr 2025

Editorial: New developments in bioinorganic and bioorganic chemistry

in Bioinorganic Chemistry

Isabel Correia
Sylvia M. Draper

Frontiers in Chemical Biology

doi 10.3389/fchbi.2025.1586841

597 views

Mini Review

Published on 28 Feb 2025

Multifaceted roles of STING in tumors: from molecular mechanisms to therapeutic strategies

in Molecular Sciences

Aashiq Hussain
Linchun Wen
Rui Wang

Frontiers in Chemical Biology

doi 10.3389/fchbi.2025.1549003

493 views

Review

Published on 25 Feb 2025

Biology and pharmacological inhibition of homeodomain-interacting protein kinases

in Molecular Sciences

Adam Štefek
Kamil Paruch

Frontiers in Chemical Biology

doi 10.3389/fchbi.2025.1441138

830 views

Editorial

Published on 14 Feb 2025

Editorial: Bioluminescence and fluorescence molecular imaging in chemical biology

in Structure, Spectroscopy & Imaging

Sung Bae Kim
Giuseppe Sancataldo

Frontiers in Chemical Biology

doi 10.3389/fchbi.2025.1568300

492 views

Editorial

Published on 07 Feb 2025

Editorial: Structure-function relationship of enzymes through a chemical lens

in Molecular Sciences

Justin M. Miller
Adam Offenbacher

Frontiers in Chemical Biology

doi 10.3389/fchbi.2025.1565931

595 views

Original Research

Published on 03 Feb 2025

Reactivity in cell culture medium and in vitro anticancer activity of 3,5-di-tert-butylcatechol: link to metal-catechol interactions

in Bioinorganic Chemistry

Aviva Levina
Debbie C. Crans
Peter A. Lay

Frontiers in Chemical Biology

doi 10.3389/fchbi.2025.1547323

596 views

Methods

Published on 21 Jan 2025

Evaluation of the microenvironment formed by interferon-β

in Structure, Spectroscopy & Imaging

Mai Yamagishi
Yutaka Hori
Nobutake Suzuki
Yu Peng
Yoshie Harada
Takashi Funatsu
Osamu Ohara
Yoshitaka Shirasaki

Frontiers in Chemical Biology

doi 10.3389/fchbi.2024.1425571

757 views

Original Research

Published on 06 Jan 2025

Exploring the NANOG-TET2 interaction interface. Effects of a selected mutation and hypothesis on the clinical correlation with anemias

in Theoretical Modeling, Structure Prediction & Design

Claudia Testi
Roberta Piacentini
Alessandro Perrone
Chiara Bartoli
Daniele Leso
Domitilla Pavia
Elisa Pistolesi
Flavio Scipione
Irene Cotronea
Marco Adinolfi Falcone

Frontiers in Chemical Biology

doi 10.3389/fchbi.2024.1517163

1,060 views

Review

Published on 20 Dec 2024

Cysteine-rich zinc finger proteins and the nuclear factor kappa-B pathway

in Bioinorganic Chemistry

Andrew T. Stoltzfus
Sarah L. J. Michel

Frontiers in Chemical Biology

doi 10.3389/fchbi.2024.1503390

882 views

Original Research

Published on 11 Oct 2024

Molecular interactions at the interface: polyoxometalates of the Anderson-Evans type and lipid membranes

in Bioinorganic Chemistry

Alina A. Pashkovskaya
Nadiia I. Gumerova
Annette Rompel
Elena E. Pohl

Frontiers in Chemical Biology

doi 10.3389/fchbi.2024.1454558

1,255 views

Original Research

Published on 10 Sep 2024

Acylfulvenes covalently interact with thioredoxin as an additional cancer target

in Molecular Sciences

Laura Slappendel
Xiaodan Liu
Michael R. Macarthur
Charles M. Sharpless
Shana J. Sturla

Frontiers in Chemical Biology

doi 10.3389/fchbi.2024.1462351

740 views