Frontiers in Chemical Biology

Original Research

Published on 14 Aug 2025

Preliminary investigation of Ru(II) complexes bearing nile red chromophores for photodynamic therapy

in Bioinorganic Chemistry

Claire Condon
Oriol Careta-Borràs
Judit Fodor
Amani B. Al Riyami
Xiao Xiao
Jianzhang Zhao
Carme Nogués
Sylvia M. Draper

Frontiers in Chemical Biology

doi 10.3389/fchbi.2025.1620562

330 views

Perspective

Accepted on 12 Aug 2025

Lessons from Metals-Containing Drugs in Diagnostic, and Theranostic Applications for Future Development of Metal-containing Non-conventional Therapeutics: Vanadium Compounds for Intratumor Administration

in Bioinorganic Chemistry

Debbie C. Crans
Adam R Miller

Frontiers in Chemical Biology

doi 10.3389/fchbi.2025.1639340

Original Research

Published on 12 Aug 2025

Carboxymethyl cellulose hydrogel doped with zinc-aspirinate as a multifunctional material: photoprotection, epithelial regeneration, and biocompatibility

in Bioinorganic Chemistry

Christina N. Banti
Fotakis Lezos
Antonios Hatzidimitriou
Sotiris K. Hadjikakou

Frontiers in Chemical Biology

doi 10.3389/fchbi.2025.1639096

232 views

Editorial

Published on 15 Jul 2025

Editorial: Insights in theoretical modelling, structure prediction and design

in Theoretical Modeling, Structure Prediction & Design

Andrea Ilari
Veronica Morea
Adriana Erica Miele

Frontiers in Chemical Biology

doi 10.3389/fchbi.2025.1653901

366 views

Brief Research Report

Published on 24 Jun 2025

Boronic acid-modified cell-penetrating peptide exhibits superior performance over natural TAT peptide

in Structure, Spectroscopy & Imaging

Pritam Ghosh

Frontiers in Chemical Biology

doi 10.3389/fchbi.2025.1610127

932 views

Specialty Grand Challenge

Published on 18 Jun 2025

Specialty grand challenges in theoretical modeling, structure prediction and design

in Theoretical Modeling, Structure Prediction & Design

Cécile Exertier
Andrea Ilari

Frontiers in Chemical Biology

doi 10.3389/fchbi.2025.1635423

602 views

Original Research

Published on 17 Jun 2025

How vanadium and manganese compounds impact cardiac mitochondrial function

in Bioinorganic Chemistry

Connor C. Dolan
Luke A. Whitcomb
Edgar Del Carpio
Lilliana Rose
Adam J. Chicco
Debbie C. Crans

Frontiers in Chemical Biology

doi 10.3389/fchbi.2025.1602602

946 views

Original Research

Published on 14 May 2025

Expanding the molecular landscape of fragments binding to trypanothione reductase, a legitimate target for drug design against human African trypanosomiasis

in Theoretical Modeling, Structure Prediction & Design

Cécile Exertier
Lorenzo Antonelli
Vittorio Brufani
Gianni Colotti
Andrea Ilari
Annarita Fiorillo

Frontiers in Chemical Biology

doi 10.3389/fchbi.2025.1605579

976 views

Original Research

Published on 12 May 2025

Exploring the heterodimer MDM2/MDM4 interaction region uncovers high-affinity peptides for therapeutic p53-reactivation

in Theoretical Modeling, Structure Prediction & Design

Marika Attili
Sonia Valentini
Maria Pesavento
Marco Ballarotto
Viviana Scognamiglio
Alfredo Pontecorvi
Antonio Macchiarulo
Fulvio Saccoccia
Fabiola Moretti

Frontiers in Chemical Biology

doi 10.3389/fchbi.2025.1576640

1,991 views

Original Research

Published on 23 Apr 2025

Structural and dynamical characterization of pRb, LTSV40 and the pRb-LTSV40 complex suggests a common mechanism for pRb inactivation

in Theoretical Modeling, Structure Prediction & Design

Carla Luciana Padilla Franzotti
Nicolas Palopoli
Juliana Palma
Gustavo Pierdominici-Sottile

Frontiers in Chemical Biology

doi 10.3389/fchbi.2025.1538350

944 views

Editorial

Published on 03 Apr 2025

Editorial: New developments in bioinorganic and bioorganic chemistry

in Bioinorganic Chemistry

Isabel Correia
Sylvia M. Draper

Frontiers in Chemical Biology

doi 10.3389/fchbi.2025.1586841

886 views

Mini Review

Published on 28 Feb 2025

Multifaceted roles of STING in tumors: from molecular mechanisms to therapeutic strategies

in Molecular Sciences

Aashiq Hussain
Linchun Wen
Rui Wang

Frontiers in Chemical Biology

doi 10.3389/fchbi.2025.1549003

866 views

Review

Published on 25 Feb 2025

Biology and pharmacological inhibition of homeodomain-interacting protein kinases

in Molecular Sciences

Adam Štefek
Kamil Paruch

Frontiers in Chemical Biology

doi 10.3389/fchbi.2025.1441138

1,310 views

Editorial

Published on 14 Feb 2025

Editorial: Bioluminescence and fluorescence molecular imaging in chemical biology

in Structure, Spectroscopy & Imaging

Sung Bae Kim
Giuseppe Sancataldo

Frontiers in Chemical Biology

doi 10.3389/fchbi.2025.1568300

750 views

Editorial

Published on 07 Feb 2025

Editorial: Structure-function relationship of enzymes through a chemical lens

in Molecular Sciences

Justin M. Miller
Adam Offenbacher

Frontiers in Chemical Biology

doi 10.3389/fchbi.2025.1565931

915 views

Original Research

Published on 03 Feb 2025

Reactivity in cell culture medium and in vitro anticancer activity of 3,5-di-tert-butylcatechol: link to metal-catechol interactions

in Bioinorganic Chemistry

Aviva Levina
Debbie C. Crans
Peter A. Lay

Frontiers in Chemical Biology

doi 10.3389/fchbi.2025.1547323

979 views