Frontiers in Chemical Biology

Original Research

Published on 05 Jun 2026

Histaminium decavanadate: a small biomimetic model to study non-covalent interactions between decavanadate and histidine side chains in proteins

in Bioinorganic Chemistry

L. F. Paredes-Pérez
N. Sánchez-López
D. Ramírez-Contreras
A. Mendoza
Laura Serrano de la Rosa
M. A. Méndez Rojas
F. J. Melendez
M. E. Castro
E. González-Vergara

Frontiers in Chemical Biology

doi 10.3389/fchbi.2026.1824850

522 views

Editorial

Published on 01 Jun 2026

Editorial: Vanadium biochemistry – highlights from the 13th international vanadium symposium

in Bioinorganic Chemistry

Isabel Correia
Debbie C. Crans

Frontiers in Chemical Biology

doi 10.3389/fchbi.2026.1860732

354 views

Original Research

Accepted on 29 May 2026

Unravelling the Effects of Proline Analogues Against Trypanosoma cruzi

in Molecular Sciences

María Sol Ballari
Flávia S. Damasceno
Marcelo L. Merli
Lucía Fargnoli
Lucas Pagura
Julia A. Cricco
Ariel Mariano Silber
Guillermo R Labadie

Frontiers in Chemical Biology

147 views

Review

Published on 28 May 2026

Structural insights into cannabinoid receptors CB1 and CB2: determinants of ligand selectivity

in Structure, Spectroscopy & Imaging

Ann Varghese
Jie Liu
Wenjing Guo
Tucker A. Patterson
Huixiao Hong

Frontiers in Chemical Biology

doi 10.3389/fchbi.2026.1830007

536 views

Original Research

Published on 21 May 2026

Tolazoline, an alpha-adrenergic antagonist, may also block xylazine at off-target sites as inferred from molecular docking

in Theoretical Modeling, Structure Prediction & Design

Giuseppe Floresta
Vincenzo Patamia
Alberto Granzotto
Davide Arillotta
Gabriele Duccio Papanti
Amira Guirguis
John M. Corkery
Giovanni Martinotti
Stefano L. Sensi
Fabrizio Schifano

Frontiers in Chemical Biology

doi 10.3389/fchbi.2026.1806456

623 views

Methods

Accepted on 19 May 2026

Engineering Mycobacterium smegmatis to Produce Oxygenic Mycolic Acids of Mycobacterium tuberculosis

in Molecular Sciences

Udipta Bohara
Liwu Li
Biswarup Mukhopadhyay
Endang Purwantini

Frontiers in Chemical Biology

208 views

Original Research

Published on 19 May 2026

Solid-state and solution complexation of dopamine with the silicotungstic Keggin polyoxometalate

in Bioinorganic Chemistry

Fredric G. Svensson
Vadim G. Kessler

Frontiers in Chemical Biology

doi 10.3389/fchbi.2026.1821236

726 views

Review

Accepted on 18 May 2026

Zinc-Binding Proteins in Alzheimer's Disease: Mechanisms, Therapeutic Potential, and Natural Compound Interventions

in Bioinorganic Chemistry

Riddhi Upadhyay
Susmita Kar
Murugan Sevanan

Frontiers in Chemical Biology

224 views

Editorial

Published on 18 May 2026

Editorial: Insights in Raman microscopy for bio-imaging applications

in Structure, Spectroscopy & Imaging

Fake Lu
Ana Maria Da Costa Ferreira

Frontiers in Chemical Biology

doi 10.3389/fchbi.2026.1872992

410 views

Editorial

Published on 15 May 2026

Editorial: Chemical biology and coordination chemistry

in Bioinorganic Chemistry

Sylvia M. Draper
Craig C. McLauchlan
Debbie C. Crans

Frontiers in Chemical Biology

doi 10.3389/fchbi.2026.1864241

608 views

Original Research

Published on 14 May 2026

Chemically induced site-specific homing of systemically administered extracellular vesicles

in Structure, Spectroscopy & Imaging

Aditya Bansal
Timothy R. DeGrado
Mukesh K. Pandey

Frontiers in Chemical Biology

doi 10.3389/fchbi.2026.1778431

849 views

Original Research

Published on 13 May 2026

Programmable Ru(II) phototherapeutics: master dials, mode switches, and coligand-controlled reactivity

in Bioinorganic Chemistry

Alisher Talgatov
Gurleen Kaur
Ge Shi
John A. Roque
Patrick C. Barrett
Debby Sunday
Tariq Sainuddin
Susy Kim
Gagan Deep
Antonio Francés-Monerris

Frontiers in Chemical Biology

doi 10.3389/fchbi.2026.1771939

1,109 views

Original Research

Published on 13 May 2026

Effect of the cancer-associated mutation H2BE76K on the structure and dynamics of nucleosome: a molecular dynamics study

in Theoretical Modeling, Structure Prediction & Design

Valentina Migliorati
Alice Patta
Felicita Cattivera
Ginevra Murano
Francesco Sessa
Alessandro Grottesi

Frontiers in Chemical Biology

doi 10.3389/fchbi.2026.1813417

492 views

Perspective

Published on 08 May 2026

Electron paramagnetic resonance as a key tool to understand the solution behavior of vanadium compounds: a chemical biology perspective

in Bioinorganic Chemistry

Eugenio Garribba

Frontiers in Chemical Biology

doi 10.3389/fchbi.2026.1811515

845 views

Original Research

Published on 07 May 2026

Comparative reactivity studies of imine-copper(II) and zinc(II) complexes containing both oxindole and benzimidazole scaffolds for biomolecules and tumor cells

in Structure, Spectroscopy & Imaging

Aline Monteiro L. Zaballa
Ana Paula Araujo de Oliveira
Rodrigo B. Fazzi
Raphael E. F. de Paiva
Katherine Tsantarlis
Carla Columbano Oliveira
Maciel Santos Luz
Sayuri Miyamoto
Ana M. da Costa Ferreira

Frontiers in Chemical Biology

doi 10.3389/fchbi.2026.1666012

858 views

Review

Published on 23 Apr 2026

Stimulated Raman scattering microscopy: fundamentals, instrumentation, and chemical imaging applications

in Structure, Spectroscopy & Imaging

Fake Lu

Frontiers in Chemical Biology

doi 10.3389/fchbi.2026.1754307

1,436 views

Review

Published on 21 Apr 2026

Biological activity of curcumin coordination complexes with second and third-row transition metals

in Bioinorganic Chemistry

Sharon Rosete-Luna
Delia Hernández-Romero
J. Antonio Cruz-Navarro
Esmeralda Sánchez-Pavón
Anell Soto-Contreras
David Morales-Morales
Raúl Colorado-Peralta

Frontiers in Chemical Biology

doi 10.3389/fchbi.2026.1797518

1,161 views

Editorial

Published on 09 Apr 2026

Editorial: Peptide and protein modifications

in Bioinorganic Chemistry

Andrea Ilari
Debbie C. Crans
Antonello Merlino

Frontiers in Chemical Biology

doi 10.3389/fchbi.2026.1838769

700 views

Brief Research Report

Published on 02 Apr 2026

Squalene-based oxygen-scavenging system for enhancing fluorescent dye stability for biosensing applications

in Quantitative and Analytical Techniques

Lijin Lian
Ijaz Gul
Xi Yuan
Zhicheng Du
Zhenglin Chen
Zhengyang Lei
Sanyang Han
Lian Zhang
Jiansong Ji
Dongmei Yu

Frontiers in Chemical Biology

doi 10.3389/fchbi.2026.1749158

968 views

Original Research

Published on 26 Mar 2026

Antibacterial potential of mono- Ru(II) and bi-metallic Ru(II)-Mn(II) inorganic compounds with phosphino-fluoroquinolone conjugates

in Bioinorganic Chemistry

Daria Wojtala
Sandra Kozieł
Jakub Łoś
Katarzyna Guz-Regner
Monika K. Lesiów
Magdalena Szmitka
Kacper Kardas
Malwin Bajkowski
Gabriela Bugla-Płoskońska
Urszula K. Komarnicka

Frontiers in Chemical Biology

doi 10.3389/fchbi.2026.1746130

1,033 views

Original Research

Published on 18 Mar 2026

Ligand-directed assembly of an iminodiacetate-hybridized molybdenum-red isopolyoxomolybdate MoV10MoVI3

in Bioinorganic Chemistry

Ingrid Gregorovic
Emir Al-Sayed
Nadiia I. Gumerova
Judith Füllborn-Ott
Ingo Ott
Gerald Giester
Annette Rompel

Frontiers in Chemical Biology

doi 10.3389/fchbi.2026.1770808

727 views

Original Research

Published on 20 Feb 2026

Roscovitine derivative optimization via molecular dynamics reveals potent and selective CDK5 binders

in Theoretical Modeling, Structure Prediction & Design

Lorenzo Botta
Giovanni Carotenuto
Manuel Arcieri
Elena Di Nisio
Valerio Perticaroli
Tiziana Castrignanò
Raffaele Saladino
Rodolfo Negri

Frontiers in Chemical Biology

doi 10.3389/fchbi.2026.1741100

686 views

Review

Published on 10 Feb 2026

Zinc-dependent aminopeptidases: new perspectives on structure, function, and biomedical applications

in Bioinorganic Chemistry

Saleem Bhat

Frontiers in Chemical Biology

doi 10.3389/fchbi.2026.1752191

1,862 views

Original Research

Published on 05 Feb 2026

Design, synthesis, reactivity, and biological activity of nitroimidazole derivatives and their copper(II) coordination compounds

in Bioinorganic Chemistry

Walter Fugarolas
Lorena Reyes-Carmona
Bruno Landeros-Rivera
Argelia Almaguer-Flores
Norah Barba-Behrens

Frontiers in Chemical Biology

doi 10.3389/fchbi.2025.1736242

1,303 views

104 articles

articles

Histaminium decavanadate: a small biomimetic model to study non-covalent interactions between decavanadate and histidine side chains in proteins

Editorial: Vanadium biochemistry – highlights from the 13th international vanadium symposium

Unravelling the Effects of Proline Analogues Against Trypanosoma cruzi

Structural insights into cannabinoid receptors CB1 and CB2: determinants of ligand selectivity

Tolazoline, an alpha-adrenergic antagonist, may also block xylazine at off-target sites as inferred from molecular docking

Engineering Mycobacterium smegmatis to Produce Oxygenic Mycolic Acids of Mycobacterium tuberculosis

Solid-state and solution complexation of dopamine with the silicotungstic Keggin polyoxometalate

Zinc-Binding Proteins in Alzheimer's Disease: Mechanisms, Therapeutic Potential, and Natural Compound Interventions

Editorial: Insights in Raman microscopy for bio-imaging applications

Editorial: Chemical biology and coordination chemistry

Chemically induced site-specific homing of systemically administered extracellular vesicles

Programmable Ru(II) phototherapeutics: master dials, mode switches, and coligand-controlled reactivity

Effect of the cancer-associated mutation H2BE76K on the structure and dynamics of nucleosome: a molecular dynamics study

Electron paramagnetic resonance as a key tool to understand the solution behavior of vanadium compounds: a chemical biology perspective

Comparative reactivity studies of imine-copper(II) and zinc(II) complexes containing both oxindole and benzimidazole scaffolds for biomolecules and tumor cells

Stimulated Raman scattering microscopy: fundamentals, instrumentation, and chemical imaging applications

Biological activity of curcumin coordination complexes with second and third-row transition metals

Editorial: Peptide and protein modifications

Squalene-based oxygen-scavenging system for enhancing fluorescent dye stability for biosensing applications

Antibacterial potential of mono- Ru(II) and bi-metallic Ru(II)-Mn(II) inorganic compounds with phosphino-fluoroquinolone conjugates

Ligand-directed assembly of an iminodiacetate-hybridized molybdenum-red isopolyoxomolybdate MoV10MoVI3

Roscovitine derivative optimization via molecular dynamics reveals potent and selective CDK5 binders

Zinc-dependent aminopeptidases: new perspectives on structure, function, and biomedical applications

Design, synthesis, reactivity, and biological activity of nitroimidazole derivatives and their copper(II) coordination compounds