In Silico Biomarker Identification for Drug Discovery

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ORIGINAL RESEARCH

Published on 02 Dec 2025

Genomics-driven drug repurposing and novel targets identification for sickle cell disease in Saudi patients

Ali Alghubayshi
Mohammad A. Alshabeeb
Dayanjan Wijesinghe
Mohammed AlAwadh
Suad Alshammari
Khalifa Alrajeh
Mona A. Alkhairi
Imadul Islam
Ahmed Alaskar

doi 10.3389/fbinf.2025.1671626

449 views

BIOINFORMATICS

Published on 24 Sep 2025

Computational drug repurposing reveals Alectinib as a potential lead targeting Cathepsin S for therapeutic developments against cancer and chronic pain

Mohammed Alrouji
Mohammed S. Alshammari
Sharif Alhajlah
Syed Tasqeeruddin
Khuzin Dinislam
Anas Shamsi
Saleha Anwar

doi 10.3389/fbinf.2025.1666573

1,609 views

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Frontiers in Bioinformatics

Frontiers in Bioinformatics

Drug Discovery in Bioinformatics

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