Plant-Based Medicines for Diabetes: Connecting Tradition and Science for Novel Therapeutics

Diabetes mellitus is a global health concern, necessitating accessible, effective, and affordable treatments. While modern pharmaceuticals have advanced diabetes management, they often present challenges such as side effects and costs. Historically, plant-based remedies have been utilized for their therapeutic potential. The isolation and purification of bioactive compounds from these natural sources are critical for harnessing their benefits.

This Research Topic focuses on integrating traditional plant wisdom with cutting-edge scientific approaches to extract, isolate, and purify plant-derived substances for diabetes management. It highlights the significance of phytochemical discoveries and mechanistic studies that demonstrate how plant-based interventions can influence glucose metabolism, enhance insulin sensitivity, and mitigate diabetes-related complications.

We invite research in areas such as:

Bioassay-guided isolation of antidiabetic secondary metabolites
Chromatographic separation methods for plant natural products
Green and sustainable isolation techniques
Isolation of complex structures and challenging compounds
Exploration of natural products from unique sources like endophytes, extremophiles, and marine organisms
Innovative isolation strategies from medicinal plants
Metabolomics-driven approaches for isolating terrestrial and marine compounds
Advances in miniaturization and automation to optimize isolation processes

This collection seeks to foster collaboration among researchers, clinicians, and policymakers in the development of plant-based diabetes treatments. It supports the Sustainable Development Goals (SDG 14: Life Below Water and SDG 15: Life on Land) by encouraging environmentally conscious practices.

We welcome Original Research, Review, and Mini Review article types for this Research Topic.

Article types and fees

This Research Topic accepts the following article types, unless otherwise specified in the Research Topic description:

• Brief Research Report
• Data Report
• Editorial
• FAIR² Data
• FAIR² DATA Direct Submission
• Hypothesis and Theory
• Methods
• Mini Review
• Original Research
• ... View all formats

Articles that are accepted for publication by our external editors following rigorous peer review incur a publishing fee charged to Authors, institutions, or funders.

Article types

This Research Topic accepts the following article types, unless otherwise specified in the Research Topic description:

• Brief Research Report
• Data Report
• Editorial
• FAIR² Data
• FAIR² DATA Direct Submission
• Hypothesis and Theory
• Methods
• Mini Review
• Original Research
• Perspective
• Review

Keywords: phytochemicals, nutraceuticals, pharmacognosy, botanicals, metabolism, glycemia, medicinal plants, traditional medicine, diabetes mellitus, herbal therapeutics, hypoglycemic agents, insulin sensitizers, clinical trials, diabetes

Important note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.