Frontiers in Natural Products

Brief Research Report

Published on 16 Dec 2025

Workflow for the isolation of natural product secondary metabolites using off-line SPE guided by gradient reverse-phase liquid chromatography (LCSPE-fast)

in Isolation and Purification

Lyamara M. O. Pavão
Marília F. Barbosa
Ana Maria S. Pereira
Quezia B. Cass
Adriana A. Lopes

Frontiers in Natural Products

doi 10.3389/fntpr.2025.1726849

278 views

Mini Review

Published on 11 Dec 2025

Bridging Eras: integrating ancient remedies with modern biotechnology to combat Non-TB skin infections

in Biological Activities of Natural Products

Nisargkumar Teli
Kinjal Upadhyay

Frontiers in Natural Products

doi 10.3389/fntpr.2025.1686049

208 views

Original Research

Accepted on 09 Dec 2025

Novel prospectives of shikimic acid and Prunus Mume extract for enhancing bioactivity on 5α-reductase and stability in cosmetic patches for acne treatment

in Biological Activities of Natural Products

Viktor Filatov
Elizaveta Patronova
Egor Ilin
Elena Kalenikova

Frontiers in Natural Products

Mini Review

Accepted on 03 Dec 2025

Zebrafish Models for Neurological Disorders: A Platform for Natural Product-Based Drug Discovery

in Biological Activities of Natural Products

Michal Korinek
Anamica Chauhan
Thiyagarajan Raviraj
Ranbir Chander Sobti
Monu Kumar Shukla

Frontiers in Natural Products

142 views

Original Research

Published on 27 Nov 2025

Evaluation of the anti-diabetic potency of Tinospora cordifolia stem against streptozotocin and high-fat diet-induced diabetic rats

in Biological Activities of Natural Products

Deeptimayee Mahapatra
Amita Beniwal
Jadav Sarma
Arijit Shome
Soumitra Goswami
Mamoni Das

Frontiers in Natural Products

doi 10.3389/fntpr.2025.1689287

508 views

Original Research

Published on 17 Nov 2025

Network pharmacology-based strategy and phytochemical screening of antioxidants suggesting the potential anti-obesity relevance of soybean food bars

in Isolation and Purification

Tedi Rustandi
Fakhriah Hayati
Fatah Nugroho
Senya Puteri Amalia
Regina Nastasya
Ahmed Mahal

Frontiers in Natural Products

doi 10.3389/fntpr.2025.1694933

598 views

Original Research

Accepted on 14 Nov 2025

Development of a comprehensive approach for the characterization of polar plant decoctions by orthogonal LC-MS reversed phase, HILIC, and NMR metabolite profiling: The case of Combretum micranthum

in Isolation and Purification

Lisa Vuadens
Robin Huber
Laurence Marcourt
Luis Manuel Quiros-Guerrero
Olivier Kirchhoffer
Arnaud Gaudry
Renata Campos Nogueira
Elhadji Assane Diop
Sidy Mohamed Seck
Wolfender Jean-Luc

Frontiers in Natural Products

178 views

Review

Published on 31 Oct 2025

The chemistry of flavonoids from Annonaceae: a comprehensive review

in Isolation and Purification

Igor R. S. Graça
Matheus V. N. Belém
Maria L. B. Pinheiro
Felipe M. A. Da Silva
Hector H. F. Koolen

Frontiers in Natural Products

doi 10.3389/fntpr.2025.1657095

1,157 views

Methods

Published on 04 Sep 2025

aNP-TRAP: a conceptual platform for in situ microbial cultivation and functional detection of antimicrobial activity

in Biological Activities of Natural Products

Maxwel Adriano Abegg

Frontiers in Natural Products

doi 10.3389/fntpr.2025.1617079

699 views

Original Research

Published on 29 Aug 2025

Novel prospectives of Paeonia lactiflora root extract as a natural modulator of LPS-induced inflammation and collagen I synthesis in skin and oral gingival cells

in Biological Activities of Natural Products

Viktor Filatov
Alina Yarovaya
Egor Ilin
Elizaveta Patronova
Vadim Tashlitsky
Elena Kalenikova

Frontiers in Natural Products

doi 10.3389/fntpr.2025.1625451

1,197 views

Original Research

Published on 29 Aug 2025

Methyl jasmonate and salicylic acid synergism enhances phloroglucinol content in shoot cultures of Astragalus fruticosus Forssk

in Natural Product Biosynthesis

Rawia Zayed
Ashraf El-Sayed
Ahmed M. Elissawy
Wafaa Ismaeil
Mohamed El-Shazly
Shaimaa Fayez

Frontiers in Natural Products

doi 10.3389/fntpr.2025.1618336

1,036 views

Review

Published on 22 Aug 2025

A review on integrative approaches in oncology: bridging ayurvedic medicine and modern cancer therapeutics

in Biological Activities of Natural Products

Sudhanshu Kumar Jha
Neha Singh
Ozasvi R. Shanker
Ishika Antil
Jaydeep Singh Baghel
Vittal Huddar
Richa Tripathi

Frontiers in Natural Products

doi 10.3389/fntpr.2025.1635197

6,437 views
7 citations

Review

Published on 23 Jul 2025

Insights into the role of Nrf2 in vitiligo pathogenesis: a target for herbal medicine

in Biological Activities of Natural Products

Abdel Qawasmeh
Mohammad Qaisiya
Areej Ishnaiwer
Dana Khdour
Shoroq Shawar
Seema Fallah
Duha Hashlamon
Hanadi Sinokrot
Alaa Kharaiwesh

Frontiers in Natural Products

doi 10.3389/fntpr.2025.1593684

2,216 views

Correction

Published on 09 Jul 2025

Correction: Affinity selection mass spectrometry (AS-MS) for prospecting ligands in natural product libraries

in Structural and Stereochemical Analysis

Bruno S. do Amaral
Marcela C. de Moraes
Carmen L. Cardoso
Quezia B. Cass

Frontiers in Natural Products

doi 10.3389/fntpr.2025.1645358

691 views

Mini Review

Published on 12 Jun 2025

Recent advancement of cyanobactins and cyanobactin prenyltransferases from 2021 to 2024

in Natural Product Biosynthesis

Abujunaid Habib Khan
Chin-Soon Phan

Frontiers in Natural Products

doi 10.3389/fntpr.2025.1616031

2,265 views

Original Research

Published on 27 May 2025

Anti-plasmodial and toxicological effects of BEEMAR - a natural formulation of harnessed honeycomb bioactive compounds suspended in enhanced marine plasma

in Biological Activities of Natural Products

Samuel Adjei
Richard Obeng-Kyeremeh
Isaac Ackah
Constance Agbemelo-Tsomafo
Daniel Amoah
Stephen Asante Obeng
Frederick Asamoah
Susan Damanka
Kwabena Owusu Danquah
Michael Preko Ntiri

Frontiers in Natural Products

doi 10.3389/fntpr.2025.1602899

4,038 views

Review

Published on 21 May 2025

Affinity selection mass spectrometry (AS-MS) for prospecting ligands in natural product libraries

in Structural and Stereochemical Analysis

Bruno S. do Amaral
Marcela C. de Moraes
Carmen L. Cardoso
Quezia B. Cass

Frontiers in Natural Products

doi 10.3389/fntpr.2025.1562501

3,251 views
2 citations

Original Research

Published on 09 May 2025

Natural compounds from ethno-medicinal plants exhibit multiple binding activities on SARS-CoV-2 spike protein receptor-binding domains

in Biological Activities of Natural Products

Trizah K. Milugo
Bethwell Owuor
Patrick W. Okanya
Kennedy Chepukosi
George F. Obiero

Frontiers in Natural Products

doi 10.3389/fntpr.2025.1597609

2,571 views
1 citation

Review

Published on 17 Apr 2025

Exploring the therapeutic potential of essential oils: a review of composition and influencing factors

in Isolation and Purification

Usama Ramadan Abdelmohsen
Abeer H. Elmaidomy

Frontiers in Natural Products

doi 10.3389/fntpr.2025.1490511

7,849 views
9 citations

Review

Published on 13 Mar 2025

A critical review on purification methods and applications of marine algal haloperoxidases

in Isolation and Purification

Abdellatif Rahim
Rania Benjamaa
Abdel Khalid Essamadi
Abdelbasset Chafik

Frontiers in Natural Products

doi 10.3389/fntpr.2025.1537097

3,076 views

Methods

Published on 24 Jan 2025

MATRIX: a platform for cultivation profiling and bioactive discovery in natural product research

in Isolation and Purification

Zeinab G. Khalil
Thulasi Sritharan
Angela A. Salim
Robert J. Capon

Frontiers in Natural Products

doi 10.3389/fntpr.2024.1532543

2,343 views
1 citation

Original Research

Published on 09 Jan 2025

LC-MS based analysis reveal antimicrobial compounds from Gabonese pharmacopoeia: chemical characterisation and cytotoxicity evaluation

in Biological Activities of Natural Products

Elvis Otogo N’nang
Paulin N. Essone
Judicael Ella Ndong
Augustin Boueya
Kossiwa Kokou
Richard Kriz
Marie Andrée N’nengué
Félix Ovono Abessolo
Bertrand Lell
Peter G. Kremsner

Frontiers in Natural Products

doi 10.3389/fntpr.2024.1478361

2,187 views

Review

Published on 07 Jan 2025

Boosting the human antiviral response in conjunction with natural plant products

in Biological Activities of Natural Products

Rashmi Srivastava
Neeraj Kumar Dubey
Megha Sharma
Harsha Kharkwal
Rajesh Bajpai
Rakesh Srivastava

Frontiers in Natural Products

doi 10.3389/fntpr.2024.1470639

14,921 views
10 citations

Mini Review

Published on 07 Jan 2025

Methods of saponin purification from Quillaja sp. for vaccine adjuvant production

in Isolation and Purification

Victor Morais
Norma Suarez
Fernando Silveira

Frontiers in Natural Products

doi 10.3389/fntpr.2024.1524624

4,301 views
2 citations

70 articles

articles

Workflow for the isolation of natural product secondary metabolites using off-line SPE guided by gradient reverse-phase liquid chromatography (LCSPE-fast)

Bridging Eras: integrating ancient remedies with modern biotechnology to combat Non-TB skin infections

Novel prospectives of shikimic acid and Prunus Mume extract for enhancing bioactivity on 5α-reductase and stability in cosmetic patches for acne treatment

Zebrafish Models for Neurological Disorders: A Platform for Natural Product-Based Drug Discovery

Evaluation of the anti-diabetic potency of Tinospora cordifolia stem against streptozotocin and high-fat diet-induced diabetic rats

Network pharmacology-based strategy and phytochemical screening of antioxidants suggesting the potential anti-obesity relevance of soybean food bars

Development of a comprehensive approach for the characterization of polar plant decoctions by orthogonal LC-MS reversed phase, HILIC, and NMR metabolite profiling: The case of Combretum micranthum

The chemistry of flavonoids from Annonaceae: a comprehensive review

aNP-TRAP: a conceptual platform for in situ microbial cultivation and functional detection of antimicrobial activity

Novel prospectives of Paeonia lactiflora root extract as a natural modulator of LPS-induced inflammation and collagen I synthesis in skin and oral gingival cells

Methyl jasmonate and salicylic acid synergism enhances phloroglucinol content in shoot cultures of Astragalus fruticosus Forssk

A review on integrative approaches in oncology: bridging ayurvedic medicine and modern cancer therapeutics

Insights into the role of Nrf2 in vitiligo pathogenesis: a target for herbal medicine

Correction: Affinity selection mass spectrometry (AS-MS) for prospecting ligands in natural product libraries

Recent advancement of cyanobactins and cyanobactin prenyltransferases from 2021 to 2024

Anti-plasmodial and toxicological effects of BEEMAR - a natural formulation of harnessed honeycomb bioactive compounds suspended in enhanced marine plasma

Affinity selection mass spectrometry (AS-MS) for prospecting ligands in natural product libraries

Natural compounds from ethno-medicinal plants exhibit multiple binding activities on SARS-CoV-2 spike protein receptor-binding domains

Exploring the therapeutic potential of essential oils: a review of composition and influencing factors

A critical review on purification methods and applications of marine algal haloperoxidases

MATRIX: a platform for cultivation profiling and bioactive discovery in natural product research

LC-MS based analysis reveal antimicrobial compounds from Gabonese pharmacopoeia: chemical characterisation and cytotoxicity evaluation

Boosting the human antiviral response in conjunction with natural plant products

Methods of saponin purification from Quillaja sp. for vaccine adjuvant production