Global Stroke Alliance for Stroke Without Frontiers Series Bridging the Gap Between Knowledge and Implementation in Global Stroke Care

Stroke remains one of the leading causes of death and disability worldwide. Although strong evidence demonstrates that up to 80% of strokes are preventable, that timely acute management reduces disability and mortality, and that early and continuous rehabilitation improves long-term outcomes, a substantial gap persists between knowledge and implementation—particularly in low- and middle-income countries (LMICs) and underserved populations within high-income nations.

The Global Stroke Alliance for Stroke Without Frontiers Series seeks to highlight global experiences and successful strategies in implementing stroke programs across the full continuum of care. This initiative aims to foster collaboration, disseminate lessons learned, and promote the translation of evidence into sustainable practice to reduce the global burden of stroke.

We welcome submissions that explore implementation research, health-system innovation, and real-world models of stroke program delivery in any setting. Topics of interest include, but are not limited to:

• Primary prevention and integration of stroke prevention into primary health care
• Pre-hospital systems and emergency stroke response
• Acute stroke management and reperfusion therapies
• Post-acute in-hospital management and early rehabilitation
• Community-based and outpatient rehabilitation, long-term follow-up, and continuity of care
• Policy, education, and advocacy initiatives supporting stroke systems of care
• Multisectoral partnerships involving health authorities, professional societies, industry, academia, and patient organizations
• Digital health, telemedicine, and data-driven approaches to improve access, quality, and monitoring of stroke care

Submissions may include original research, implementation frameworks, or policy analyses showcasing how diverse countries and stakeholders are closing the gap between evidence and action.

By compiling these examples, this Research Topic aims to provide practical guidance and inspiration for health systems worldwide to implement effective and equitable stroke programs—ultimately advancing the goal of stroke without frontiers.

Article types and fees

This Research Topic accepts the following article types, unless otherwise specified in the Research Topic description:

• Brief Research Report
• Case Report
• Classification
• Clinical Trial
• Community Case Study
• Data Report
• Editorial
• FAIR² Data
• General Commentary
• ... View all formats

Articles that are accepted for publication by our external editors following rigorous peer review incur a publishing fee charged to Authors, institutions, or funders.

Article types

This Research Topic accepts the following article types, unless otherwise specified in the Research Topic description:

• Brief Research Report
• Case Report
• Classification
• Clinical Trial
• Community Case Study
• Data Report
• Editorial
• FAIR² Data
• General Commentary
• Hypothesis and Theory
• Methods
• Mini Review
• Opinion
• Original Research
• Perspective
• Policy and Practice Reviews
• Review
• Study Protocol
• Systematic Review
• Technology and Code

Keywords: stroke care implementation, acute stroke, Stroke care; implementation science; prevention; acute management; rehabilitation; health systems; primary health care; telemedicine; global health; LMICs. management in low middle income countries, telemedicine

Important note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.