Cyp2c93 | List of Frontiers open access articles

Original Research

Published on 06 Apr 2020

A Pharmacogenetically Guided Acenocoumarol Dosing Algorithm for Chilean Patients: A Discovery Cohort Study

in Pharmacogenetics and Pharmacogenomics

Angela Roco
Elena Nieto
Marcelo Suárez
Mario Rojo
Maria Paz Bertoglia
Gabriel Verón
Francisca Tamayo
Annabella Arredondo
Daniela Cruz
Jessica Muñoz

Frontiers in Pharmacology

doi 10.3389/fphar.2020.00325

9,864 views
16 citations

Original Research

Published on 28 Jan 2020

Phenprocoumon Dose Requirements, Dose Stability and Time in Therapeutic Range in Elderly Patients With CYP2C9 and VKORC1 Polymorphisms

in Pharmacogenetics and Pharmacogenomics

Katharina Luise Schneider
Melanie Kunst
Ann-Kristin Leuchs
Miriam Böhme
Klaus Weckbecker
Kathrin Kastenmüller
Markus Bleckwenn
Stefan Holdenrieder
Christoph Coch
Gunther Hartmann

Frontiers in Pharmacology

doi 10.3389/fphar.2019.01620

5,758 views
3 citations

Original Research

Published on 07 Jun 2017

Warfarin Anticoagulation Therapy in Caribbean Hispanics of Puerto Rico: A Candidate Gene Association Study

in Pharmacogenetics and Pharmacogenomics

Karla Claudio-Campos
Aurora Labastida
Alga Ramos
Andrea Gaedigk
Jessicca Renta-Torres
Dariana Padilla
Giselle Rivera-Miranda
Stuart A. Scott
Gualberto Ruaño
Carmen L. Cadilla

Frontiers in Pharmacology

doi 10.3389/fphar.2017.00347

6,209 views
20 citations

Original Research

Published on 20 Dec 2023

Screening and validation of double allele-specific binding F-primers for the measurement of antihypertensive pharmacogenomics

in Precision Medicine

Yang Ping
Su Quanlin
Hu Yue
Zhang Jing
Lan Wenjun

Frontiers in Medicine

doi 10.3389/fmed.2023.1269221

2,510 views

Original Research

Published on 21 May 2025

Mathematical modeling of pharmacokinetics and pharmacodynamics of losartan in relation to CYP2C9 allele variants

in Multiscale Mechanistic Modeling

Dmitry Babaev
Elena Kutumova
Fedor Kolpakov

Frontiers in Systems Biology

doi 10.3389/fsysb.2025.1504077

3,297 views
2 citations

Original Research

Published on 30 Apr 2025

The impact of CYP2C9, VKORC1, and CYP4F2 polymorphisms on warfarin dose requirement in Saudi patients

in Pharmacogenetics and Pharmacogenomics

Salha Jokhab
Maha M. AlRasheed
Dana Bakheet
Abdulkareem AlMomen
Nouf AlAboud
Farhad Kamali

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1547142

3,397 views
4 citations

Review

Published on 12 Aug 2025

Role of pharmacogenomics for prevention of hypersensitivity reactions induced by aromatic antiseizure medications

in Pharmacogenetics and Pharmacogenomics

Angel T. Alvarado
Amparo Iris Zavaleta
César Li-Amenero
María R. Bendezú
Jorge A. Garcia
Haydee Chávez
Juan J. Palomino-Jhong
Felipe Surco-Laos
Doris Laos-Anchante
Elizabeth J. Melgar-Merino

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1640401

3,013 views
3 citations

Mini Review

Published on 25 Apr 2022

An Updated Review of Genetic Associations With Severe Adverse Drug Reactions: Translation and Implementation of Pharmacogenomic Testing in Clinical Practice

in Pharmacogenetics and Pharmacogenomics

Chuang-Wei Wang
Ivan Arni C. Preclaro
Wei-Hsiang Lin
Wen-Hung Chung

Frontiers in Pharmacology

doi 10.3389/fphar.2022.886377

15,025 views
41 citations

Original Research

Published on 20 Jan 2021

Genetic and Non-genetic Factors Contributing to the Significant Variation in the Plasma Trough Concentration-to-Dose Ratio of Valproic Acid in Children With Epilepsy

in Pediatric Neurology

Ze-Yue Xu
Hong-Li Guo
Ling Li
Min Zhang
Xia Jing
Ze-Jun Xu
Jin-Chun Qiu
Xiao-Peng Lu
Xuan-Sheng Ding
Feng Chen

Frontiers in Pediatrics

doi 10.3389/fped.2020.599044

4,668 views
8 citations

Original Research

Published on 31 May 2017

Effect of Genetic Variability in the CYP4F2, CYP4F11, and CYP4F12 Genes on Liver mRNA Levels and Warfarin Response

in Pharmacogenetics and Pharmacogenomics

J. E. Zhang
Kathrin Klein
Andrea L. Jorgensen
Ben Francis
Ana Alfirevic
Stephane Bourgeois
Panagiotis Deloukas
Ulrich M. Zanger
Munir Pirmohamed

Frontiers in Pharmacology

doi 10.3389/fphar.2017.00323

9,155 views
24 citations

Original Research

Published on 10 Jun 2022

Determination of Pleiotropic Effect of Warfarin in VKORC1 and CYP2C9 Genotypes in Patients With Heart Valve Replacement

in Cardiovascular Therapeutics

Huma Shafique
Naeem Mahmood Ashraf
Amir Rashid
Asifa Majeed
Tayyaba Afsar
Ann K. Daly
Ali Almajwal
Nawaf W. Alruwaili
Azmat Ullah Khan
Suhail Razak

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2022.895169

4,070 views
2 citations

Original Research

Published on 07 May 2020

Possible Genetic Determinants of Response to Phenytoin in a Group of Colombian Patients With Epilepsy

in Drugs Outcomes Research and Policies

Carlos Alberto Calderon-Ospina
Jubby Marcela Galvez
Claudia López-Cabra
Natalia Morales
Carlos Martín Restrepo
Jesús Rodríguez
Fabio Ancízar Aristizábal-Gutiérrez
Alberto Velez-van-Meerbeke
Paul Laissue
Dora Janeth Fonseca-Mendoza

Frontiers in Pharmacology

doi 10.3389/fphar.2020.00555

5,896 views
17 citations

Original Research

Published on 02 Nov 2012

Frequencies of 23 Functionally Significant Variant Alleles Related with Metabolism of Antineoplastic Drugs in the Chilean Population: Comparison with Caucasian and Asian Populations

in Pharmacogenetics and Pharmacogenomics

Angela Margarita Roco
Luis Abel Quiñones
José A G Agúndez
Elena García-Martín
Valentina Squicciarini
Carla Estefania Miranda
Joselyn Garay
Nancy Farfán
Iván Nicolás Saavedra
Dante Daniel Caceres

Frontiers in Genetics

doi 10.3389/fgene.2012.00229

11,590 views
69 citations

Original Research

Published on 23 Sep 2022

A genome-wide association study of plasma concentrations of warfarin enantiomers and metabolites in sub-Saharan black-African patients

in Pharmacogenetics and Pharmacogenomics

Innocent G. Asiimwe
Marc Blockman
Karen Cohen
Clint Cupido
Claire Hutchinson
Barry Jacobson
Mohammed Lamorde
Jennie Morgan
Johannes P. Mouton
Doreen Nakagaayi

Frontiers in Pharmacology

doi 10.3389/fphar.2022.967082

6,466 views
16 citations

Original Research

Published on 19 Sep 2025

Prevalence of risk phenotypes associated with CYP2C92, 3, and VKORC1 c.-1639G>A genetic polymorphisms in world populations: implications in clinical practice

in Pharmacogenetics and Pharmacogenomics

Mohitosh Biswas
Murshadul Alam Murad
Maliheh Ershadian
Most. Sumaiya Khatun Kali
Maw Shin Sim
Baharudin Ibrahim
Chonlaphat Sukasem

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1597379

2,667 views
1 citation

Articles

A Pharmacogenetically Guided Acenocoumarol Dosing Algorithm for Chilean Patients: A Discovery Cohort Study

Phenprocoumon Dose Requirements, Dose Stability and Time in Therapeutic Range in Elderly Patients With CYP2C9 and VKORC1 Polymorphisms

Warfarin Anticoagulation Therapy in Caribbean Hispanics of Puerto Rico: A Candidate Gene Association Study

Screening and validation of double allele-specific binding F-primers for the measurement of antihypertensive pharmacogenomics

Mathematical modeling of pharmacokinetics and pharmacodynamics of losartan in relation to CYP2C9 allele variants

The impact of CYP2C9, VKORC1, and CYP4F2 polymorphisms on warfarin dose requirement in Saudi patients

Role of pharmacogenomics for prevention of hypersensitivity reactions induced by aromatic antiseizure medications

An Updated Review of Genetic Associations With Severe Adverse Drug Reactions: Translation and Implementation of Pharmacogenomic Testing in Clinical Practice

Genetic and Non-genetic Factors Contributing to the Significant Variation in the Plasma Trough Concentration-to-Dose Ratio of Valproic Acid in Children With Epilepsy

Effect of Genetic Variability in the CYP4F2, CYP4F11, and CYP4F12 Genes on Liver mRNA Levels and Warfarin Response

Determination of Pleiotropic Effect of Warfarin in VKORC1 and CYP2C9 Genotypes in Patients With Heart Valve Replacement

Possible Genetic Determinants of Response to Phenytoin in a Group of Colombian Patients With Epilepsy

Frequencies of 23 Functionally Significant Variant Alleles Related with Metabolism of Antineoplastic Drugs in the Chilean Population: Comparison with Caucasian and Asian Populations

A genome-wide association study of plasma concentrations of warfarin enantiomers and metabolites in sub-Saharan black-African patients

Prevalence of risk phenotypes associated with CYP2C9*2, *3, and VKORC1 c.-1639G>A genetic polymorphisms in world populations: implications in clinical practice

Prevalence of risk phenotypes associated with CYP2C92, 3, and VKORC1 c.-1639G>A genetic polymorphisms in world populations: implications in clinical practice