De Novo Organ Initiation | List of Frontiers open access articles

Original Research

Published on 09 Oct 2025

Development of targeted drugs for diabetic retinopathy using Mendelian randomized pharmacogenomics

in Diabetes: Molecular Mechanisms

Guodan Liu
Miao Tian
Xinge Li
Xichen Wang
Songhao Zhang
Gali Bai
Xuyang Zhang

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1632691

773 views

Original Research

Published on 09 Oct 2025

Sustainable consumption meets conspicuous leisure: a dual-theory exploration in luxury hospitality

in Behaviors and Behavior Change in Tourism

Priyanka Shrivastava
Sergio Romero Hernandez
Omar Romero Hernandaz

Frontiers in Sustainable Tourism

doi 10.3389/frsut.2025.1640400

950 views

Policy and Practice Reviews

Published on 09 Oct 2025

Managing fisheries and ecosystems: current good practices and the EcoScope project experience

in Marine Fisheries, Aquaculture and Living Resources

Georgi M. Daskalov
Santiago de la Puente
Marco Scotti
Stefania Klayn
Marie Briguglio
Gianpaolo Coro
Gideon Gal
Johanna J. Heymans
Ana Rodriguez-Perez
Jeroen Gerhard Steenbeek

Frontiers in Marine Science

doi 10.3389/fmars.2025.1640487

934 views

Review

Published on 09 Oct 2025

Mechanical signal-chromatin interactions: molecular networks from nuclear membrane force transmission to epigenetic regulation

in Gene and Cell Therapy

Shili Yang
Huaiquan Liu
Bo Chen
Haiyang Kou
Lingyan Lai
Xinyan Zhang
Yunling Xu
Yu Sun

Frontiers in Medicine

doi 10.3389/fmed.2025.1631645

558 views

Original Research

Published on 09 Oct 2025

Remote sensing and MaxEnt modeling of canopy and non-canopy forest tree species in Taraba State for biodiversity conservation and ecosystem management

in Forest Management

Ibrahim Inuwa Yahaya
Changcheng Wang
Chukwuka Prince Ogbue
Mohammed Sani Yahaya

Frontiers in Forests and Global Change

doi 10.3389/ffgc.2025.1631859

498 views

Original Research

Published on 09 Oct 2025

Assessment of benzodiazepine dosing in status epilepticus patients in the emergency department

in Epilepsy

Raniah Ibrahim Aljadeed
Amenah Alkaf
Daad Alhajlbrahim
Huda Alewairdhi
Ghadah Asaad Assiri
Rana Aljadeed
Haya Almalag
Nora Kalagi

Frontiers in Neurology

doi 10.3389/fneur.2025.1645435

628 views

Systematic Review

Published on 09 Oct 2025

Comparative analysis of postoperative outcomes following surgical and transcatheter edge-to-edge mitral valve repair for secondary mitral regurgitation: a meta-analysis & systematic review

in Cardiovascular Surgery

Dudy A. Hanafy
Adrian R. Sudirman
Sari Rahmawati
Hendry R. Satria
Safitri
Stefanus Nursalim
Muhammad R. Bachmid
Dwi G. Fardhani
Tri W. Soetisna
Sugisman

Frontiers in Surgery

doi 10.3389/fsurg.2025.1645272

389 views

Review

Published on 09 Oct 2025

Integrating natural non-pharmaceutical therapies into medical tourism: a dynamic health portrait-driven model for proactive older adult health and public health services

in Aging and Public Health

Mingyu Liu
Boyuan Wang

Frontiers in Public Health

doi 10.3389/fpubh.2025.1580082

617 views

Review

Published on 09 Oct 2025

A review of immunotherapy for bone tumors

in Cancer Immunity and Immunotherapy

Chenwen Wang
Zixiong Chen
Haokun Mo
Jiang Wang
Wei Zhou

Frontiers in Immunology

doi 10.3389/fimmu.2025.1580598

843 views

Original Research

Published on 09 Oct 2025

Deep learning for 3D reconstruction and trajectory prediction of dust and polluted aerosols in educational environments

in Big Data, AI, and the Environment

Zhen Wang
Ruijuan Han

Frontiers in Environmental Science

doi 10.3389/fenvs.2025.1582806

884 views

Original Research

Published on 09 Oct 2025

Uncovering psychologically mediated pathways to cardiovascular diseases: depressive symptoms as a mediator between childhood maltreatment and single or multiple cardiovascular disease comorbidities

in Public Mental Health

Peilin Yu
Hong Zhang
Xinxin Zhang
Ping Zeng
Chu Zheng
Ke Wang

Frontiers in Psychiatry

doi 10.3389/fpsyt.2025.1560961

534 views

Original Research

Published on 09 Oct 2025

Cost-effectiveness analysis of cabozantinib plus atezolizumab for advanced hepatocellular carcinoma

in Drugs Outcomes Research and Policies

Yan Zhu
Cheng He
Shi-Chao Cao
Hui-Jun Li
Ru-Xue Cai
Zhao-Jun Bai
Tong-Xia Xia

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1556304

1,545 views

Case Report

Published on 09 Oct 2025

Salvage sequential integrated boost radiotherapy followed by sintilimab–bevacizumab in cervical small-cell carcinoma with >10 brain metastases: A 3-year survivor case report

in Cancer Immunity and Immunotherapy

Yuanyuan Xu
Xiang Gong
Huailin He
Xiangyu Deng
Zhenhua Zhang
Qinglian Wen
Dan Li

Frontiers in Immunology

doi 10.3389/fimmu.2025.1590848

374 views

Systematic Review

Published on 09 Oct 2025

Impact of percutaneous coronary intervention with different guidance modalities in patients with coronary artery lesions: a network meta-analysis and systematic review

in Atherosclerosis and Vascular Medicine

Tao Jiang
Jie Huang
Lisha Luo
Miaoling Li
Gong Chen

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2025.1526188

1,468 views

Systematic Review

Published on 09 Oct 2025

Didactic strategies for conceptual understanding and motivation in university mathematics: a systematic review

in Higher Education

Darwin Castillo
Javier Carrión
Cristian Chamba
Yuliana Jiménez-Gaona
María José Rodríguez-Álvarez
Vasudevan Lakshminarayanan

Frontiers in Education

doi 10.3389/feduc.2025.1536470

521 views

Brief Research Report

Published on 09 Oct 2025

Investigating depression pathways in a clinical sample: childhood adversity, reward, and threat processing

in Psychopathology

Lia-Ecaterina Oltean
Andrei C. Miu
Aurora Szentágotai-Tǎtar

Frontiers in Psychology

doi 10.3389/fpsyg.2025.1448585

1,172 views

Articles

Development of targeted drugs for diabetic retinopathy using Mendelian randomized pharmacogenomics

Sustainable consumption meets conspicuous leisure: a dual-theory exploration in luxury hospitality

Managing fisheries and ecosystems: current good practices and the EcoScope project experience

Mechanical signal-chromatin interactions: molecular networks from nuclear membrane force transmission to epigenetic regulation

Remote sensing and MaxEnt modeling of canopy and non-canopy forest tree species in Taraba State for biodiversity conservation and ecosystem management

Assessment of benzodiazepine dosing in status epilepticus patients in the emergency department

Comparative analysis of postoperative outcomes following surgical and transcatheter edge-to-edge mitral valve repair for secondary mitral regurgitation: a meta-analysis & systematic review

Integrating natural non-pharmaceutical therapies into medical tourism: a dynamic health portrait-driven model for proactive older adult health and public health services

A review of immunotherapy for bone tumors

Deep learning for 3D reconstruction and trajectory prediction of dust and polluted aerosols in educational environments

Uncovering psychologically mediated pathways to cardiovascular diseases: depressive symptoms as a mediator between childhood maltreatment and single or multiple cardiovascular disease comorbidities

Cost-effectiveness analysis of cabozantinib plus atezolizumab for advanced hepatocellular carcinoma

Salvage sequential integrated boost radiotherapy followed by sintilimab–bevacizumab in cervical small-cell carcinoma with >10 brain metastases: A 3-year survivor case report

Impact of percutaneous coronary intervention with different guidance modalities in patients with coronary artery lesions: a network meta-analysis and systematic review

Didactic strategies for conceptual understanding and motivation in university mathematics: a systematic review

Investigating depression pathways in a clinical sample: childhood adversity, reward, and threat processing