De Novo Organ Initiation | List of Frontiers open access articles

Original Research

Published on 08 Oct 2025

Addition of bevacizumab to gefitinib plus chemotherapy as first-line therapy in EGFR L858R mutate advanced non-small cell lung cancer patients

in Pharmacology of Anti-Cancer Drugs

Lingli Lei
Xiang Zhan
Jixian Li
Yi Ding
Jiaxin Li
Fengge Zhou
Alei Feng
Xiaomei Li
Zhe Yang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1503171

517 views

Core Concept

Published on 08 Oct 2025

Treating Parkinson’s Disease With Electric Pulses in the Brain

in Neuroscience and Psychology

Shamsa H. Alshamsi
Lidya K. Yassin
Mohammad I. K. Hamad
Safa Shehab

Frontiers for Young Minds

doi 10.3389/frym.2025.1477905

576 views

Original Research

Published on 08 Oct 2025

Development and effectiveness of multimedia interactive learning Scratch Wabimendu (World Indonesian Cultural Heritage)

in Digital Learning Innovations

Ika Ari Pratiwi
Anita Rahmawati
Mohamed Nor Azhari Azman
Nur Fajrie
Hisbulloh Als Mustofa

Frontiers in Education

doi 10.3389/feduc.2025.1628412

404 views

Original Research

Published on 08 Oct 2025

The systemic marginalisation of long-term casualised researchers in UK higher education

in Work, Employment and Organizations

Cecile B. Menard

Frontiers in Sociology

doi 10.3389/fsoc.2025.1626458

352 views

Opinion

Published on 08 Oct 2025

Temporal concentration and phase synchronization in phase-amplitude coupling

in Learning and Memory

Marjan Nosouhi
Stefan Treue
Moein Esghaei

Frontiers in Behavioral Neuroscience

doi 10.3389/fnbeh.2025.1615997

1,964 views

Original Research

Published on 08 Oct 2025

Risk factors and clinical outcomes of severe postoperative hypoxaemia following surgical repair of Stanford type A aortic dissection: a retrospective cohort study

in Intensive Care Medicine and Anesthesiology

Min Lin
Yuping Xiang
Tianhui Luo
Ling Zeng
Jingxiu Fan

Frontiers in Medicine

doi 10.3389/fmed.2025.1603262

262 views

Original Research

Published on 08 Oct 2025

Beyond mindfulness: the importance of body compassion in colorectal cancer distress

in Psycho-Oncology

Lauren A. Zimmaro
Aimee J. Christie
Andrew Nicklawsky
Jennifer K. Altman
James W. Carson
Christopher H. Lieu
Carolyn Y. Fang
Jennifer B. Reese

Frontiers in Psychology

doi 10.3389/fpsyg.2025.1618389

2,587 views

Original Research

Published on 08 Oct 2025

Analysis of influential factors in laparoscopic myomectomy and estimation of hidden blood loss

in Obstetrics and Gynecological Surgery

Jingjing Lu
Lili Chu
Liliang Shen

Frontiers in Surgery

doi 10.3389/fsurg.2025.1614919

470 views

Original Research

Published on 08 Oct 2025

Unveiling the impact of interferon genes on the immune microenvironment of triple-negative breast cancer: identification of therapeutic targets

in RNA Bioinformatics

Ying Liu
Jiayi Cai
Aamir Fahira
Kai Zhuang
Jiaojiao Wang
Zhi Zhang
Lin Yan
Yong Liu
Defang Ouyang
Zunnan Huang

Frontiers in Bioinformatics

doi 10.3389/fbinf.2025.1629526

735 views

Review

Published on 08 Oct 2025

Unraveling brucellosis: advances in pathogenesis, diagnostic strategies, therapeutic innovations, and public health perspectives

in Infectious Diseases: Pathogenesis and Therapy

Abdulaziz M. Almuzaini
Ayman Elbehiry

Frontiers in Medicine

doi 10.3389/fmed.2025.1629008

825 views

Case Report

Published on 08 Oct 2025

Case Report: Efficacy of preoperative conversion therapy with lenvatinib, toripalimab, and hepatic arterial infusion chemotherapy in an advanced hepatocellular carcinoma

in Gastrointestinal Cancers: Hepato Pancreatic Biliary Cancers

Jing Mao
Hengzhi Zhang
Xingxia Yang
Yanjun Yao
Xu Sun
Qiang Yan

Frontiers in Oncology

doi 10.3389/fonc.2025.1627281

671 views

Original Research

Published on 08 Oct 2025

Analysis of global, regional, and national burdens of neonatal encephalopathy from 1990 to 2021: insights from the Global Burden of Disease Study 2021

in Children and Health

Shujun Tan
Shala Mageziyi
Li Long
Naiyiman Dilimulati
Zhang Hui
Nuerya Rejiafu

Frontiers in Public Health

doi 10.3389/fpubh.2025.1627448

415 views

Original Research

Published on 08 Oct 2025

Auricular acupuncture as stress-relieving intervention for parents of infants in the neonatal intensive care unit: insights gained from a pilot study

in Maternal Health

Helle Haslund-Thomsen
Bettina Svelle
Christina Skoda
Malene Horskjær
Marie Germund Nielsen

Frontiers in Global Women's Health

doi 10.3389/fgwh.2025.1597105

442 views

Original Research

Published on 08 Oct 2025

Revised Peck’s formula for estimating pipeline’s settlement under the coupling effect of tunnelling and vehicle load

in Structural Sensing, Control and Asset Management

Shu Peng

Frontiers in Built Environment

doi 10.3389/fbuil.2025.1607111

750 views

Study Protocol

Published on 08 Oct 2025

Digital home-based multimodal prehabilitation of colorectal cancer patients prior to surgery (the dHOPE study): a non-inferiority clinical trial protocol

in Personalized Medicine

Guro Kleve
Chiara Dalla Santa
Felicia Kristiansen
Marita Tegnander
Victoria Buch
Cecilie Steen Hagemann
Marianne Helgheim
Parasto Engene
Henri Pesonen
Maiken Kojen Kleveland

Frontiers in Digital Health

doi 10.3389/fdgth.2025.1609678

3,020 views

Case Report

Published on 08 Oct 2025

Case report: Abscopal response and reversal of PD-1 resistance in a patient with nephroblastoma following radiofrequency ablation

in Genitourinary Oncology

Mengyang Ju
Mingjuan Sun
Wenfeng Li
Sheng Zhang

Frontiers in Oncology

doi 10.3389/fonc.2025.1640409

142 views

Articles

Addition of bevacizumab to gefitinib plus chemotherapy as first-line therapy in EGFR L858R mutate advanced non-small cell lung cancer patients

Treating Parkinson’s Disease With Electric Pulses in the Brain

Development and effectiveness of multimedia interactive learning Scratch Wabimendu (World Indonesian Cultural Heritage)

The systemic marginalisation of long-term casualised researchers in UK higher education

Temporal concentration and phase synchronization in phase-amplitude coupling

Risk factors and clinical outcomes of severe postoperative hypoxaemia following surgical repair of Stanford type A aortic dissection: a retrospective cohort study

Beyond mindfulness: the importance of body compassion in colorectal cancer distress

Analysis of influential factors in laparoscopic myomectomy and estimation of hidden blood loss

Unveiling the impact of interferon genes on the immune microenvironment of triple-negative breast cancer: identification of therapeutic targets

Unraveling brucellosis: advances in pathogenesis, diagnostic strategies, therapeutic innovations, and public health perspectives

Case Report: Efficacy of preoperative conversion therapy with lenvatinib, toripalimab, and hepatic arterial infusion chemotherapy in an advanced hepatocellular carcinoma

Analysis of global, regional, and national burdens of neonatal encephalopathy from 1990 to 2021: insights from the Global Burden of Disease Study 2021

Auricular acupuncture as stress-relieving intervention for parents of infants in the neonatal intensive care unit: insights gained from a pilot study

Revised Peck’s formula for estimating pipeline’s settlement under the coupling effect of tunnelling and vehicle load

Digital home-based multimodal prehabilitation of colorectal cancer patients prior to surgery (the dHOPE study): a non-inferiority clinical trial protocol

Case report: Abscopal response and reversal of PD-1 resistance in a patient with nephroblastoma following radiofrequency ablation