Deep Space | List of Frontiers open access articles

Review

Published on 01 Oct 2025

Cell-free mitochondrial DNA as a pro-inflammatory agent in blood circulation: mechanisms, therapeutic implications, and clinical challenges in immune dysregulation

in Inflammation

Yangyang Zhao
Chunlei Wu
Xiaoxue Liang
Mengjiao Yang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1640748

1,078 views

Original Research

Published on 01 Oct 2025

The moderating role of social support in the relationship between alexithymia and problematic smartphone use among Chinese depressed adolescents: a cross-sectional study

in Adolescent and Young Adult Psychiatry

Shumiao Liu
Yufeng Wu
Fengxia Sun
Yongjie Zhou
Aihua Yin

Frontiers in Psychiatry

doi 10.3389/fpsyt.2025.1650290

412 views

Systematic Review

Published on 01 Oct 2025

Efficacy, immunogenicity, and safety of pneumococcal conjugate vaccine in children: a systematic review and meta-analysis

in Pediatric Infectious Diseases

Qin Dai
Yujie Dong
Jing Wu
Qiyan Peng

Frontiers in Pediatrics

doi 10.3389/fped.2025.1652946

1,667 views

Methods

Published on 01 Oct 2025

Key considerations for ELISA-based quantification of diverse amyloid beta forms in murine brain homogenates

in Neuroscience Methods and Techniques

Nicole G. Metzendorf
Dag Sehlin
Greta Hultqvist

Frontiers in Neuroscience

doi 10.3389/fnins.2025.1645952

2,200 views

Original Research

Published on 01 Oct 2025

Migraine is associated with a higher risk of ischemic and hemorrhagic stroke: an analysis of the All of Us database

in Headache

Nick Seah
Catherine D. Chong
Oana M. Dumitrascu
Todd J. Schwedt
Zhichao Cao
Teresa Wu

Frontiers in Pain Research

doi 10.3389/fpain.2025.1646142

225 views

Brief Research Report

Published on 01 Oct 2025

Paediatric CSF acylcarnitine reference ranges

in Metabolomics

Ontefetse Neo Plaatjie
A. Marceline Tutu Van Furth
Regan Solomons
Martijn Van Der Kuip
Shayne Mason

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1643667

1,039 views

Systematic Review

Published on 01 Oct 2025

Association of overt hypothyroidism with risks of cognitive impairment: a meta-analysis and systematic review

in Thyroid Endocrinology

Jinxin Zhu
Jialu Xu
Zhaoqing Li
Jia Liu

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1643589

1,039 views

Original Research

Published on 01 Oct 2025

MGL/CLEC10A is an important C-type lectin receptor activated in the innate immune response to Mycobacterium tuberculosis and is suppressed in people with HIV

in Microbial Immunology

Sarah E. Browning
Preeti Bharaj
Xiuzhen Fan
Harrison Nguyen
Alex J. Holloway
Kubra F. Naqvi
Joshua G. Lisinicchia
Reina N. Paez
Sadhana Chauhan
Matthew B. Huante

Frontiers in Immunology

doi 10.3389/fimmu.2025.1597281

927 views

Original Research

Published on 01 Oct 2025

A novel transcatheter tricuspid annuloplasty for severe tricuspid valve regurgitation via the K-clip™ system: early experience in China

in General Cardiovascular Medicine

Rongfeng Xu
Lijuan Chen
Xiaoli Zhang
Xiuxia Ding
Zhen Wang
Qitong Lu
Xiaoguo Zhang
Jiandong Ding
Genshan Ma

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2025.1598644

381 views

Original Research

Published on 01 Oct 2025

Decoding honey-sweet flavored flue-cured tobacco from Guizhou with data science and flavoromics by volatile and cell wall components

in Analytical Chemistry

Risheng Zhong
Zhenchun Sun
Liang Feng
Haitao Chen
Shuqi Wang
Yechun Lin
Jie Sun
Ning Zhang
Huiying Zhang
Feng Wang

Frontiers in Chemistry

doi 10.3389/fchem.2025.1613828

1,169 views

Original Research

Published on 01 Oct 2025

Examining the benefit of L2 language proficiency on academic performance using Bayesian logistic modeling

in Performance Science

Taocheng Jiang
ZhiYi Zheng
Feng Wang

Frontiers in Psychology

doi 10.3389/fpsyg.2025.1613695

2,230 views

Original Research

Published on 01 Oct 2025

Critical appraisal of studies evaluating prevalence of attention deficit hyperactivity disorder

in ADHD

Michelle Tivadar
Sara Popit
Igor Locatelli
Matej Stuhec

Frontiers in Psychiatry

doi 10.3389/fpsyt.2025.1646618

2,300 views

Original Research

Published on 01 Oct 2025

Heart rates, facial expressions and self-reports: a multimodal longitudinal approach of learners' emotions in the foreign language classroom

in AI for Human Learning and Behavior Change

Delphine Guedat-Bittighoffer
Abderrazzaq Moufidi
Jean-Marc Dewaele
David Rousseau
Hugo Voyneau
Pejman Rasti

Frontiers in Artificial Intelligence

doi 10.3389/frai.2025.1604110

1,158 views

Original Research

Published on 01 Oct 2025

Analysis of flavor characteristics of peanut porridge using gas chromatography-ion mobility spectrometry combined with intelligent sensory technology

in Food Chemistry

Bihua Yuan
Yun Tian
Xuan Zhu
Kaiqi Cheng
Wengang Jin
Qing Liu
Jing Li
Haiyan Sun

Frontiers in Nutrition

doi 10.3389/fnut.2025.1609333

549 views

Methods

Published on 01 Oct 2025

Evaluating chatbot architectures for public service delivery: balancing functionality, safety, ethics, and adaptability

in Politics of Technology

Theodoros Papadopoulos
Charalampos Alexopoulos
Yannis Charalabidis

Frontiers in Political Science

doi 10.3389/fpos.2025.1601440

575 views

Mini Review

Published on 01 Oct 2025

The versatility of algae in addressing the global sustainability challenges

in Industrial Biotechnology

Bishnu Dev Das
Ajaya Bhattarai

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1621817

961 views

Articles

Cell-free mitochondrial DNA as a pro-inflammatory agent in blood circulation: mechanisms, therapeutic implications, and clinical challenges in immune dysregulation

The moderating role of social support in the relationship between alexithymia and problematic smartphone use among Chinese depressed adolescents: a cross-sectional study

Efficacy, immunogenicity, and safety of pneumococcal conjugate vaccine in children: a systematic review and meta-analysis

Key considerations for ELISA-based quantification of diverse amyloid beta forms in murine brain homogenates

Migraine is associated with a higher risk of ischemic and hemorrhagic stroke: an analysis of the All of Us database

Paediatric CSF acylcarnitine reference ranges

Association of overt hypothyroidism with risks of cognitive impairment: a meta-analysis and systematic review

MGL/CLEC10A is an important C-type lectin receptor activated in the innate immune response to Mycobacterium tuberculosis and is suppressed in people with HIV

A novel transcatheter tricuspid annuloplasty for severe tricuspid valve regurgitation via the K-clip™ system: early experience in China

Decoding honey-sweet flavored flue-cured tobacco from Guizhou with data science and flavoromics by volatile and cell wall components

Examining the benefit of L2 language proficiency on academic performance using Bayesian logistic modeling

Critical appraisal of studies evaluating prevalence of attention deficit hyperactivity disorder

Heart rates, facial expressions and self-reports: a multimodal longitudinal approach of learners' emotions in the foreign language classroom

Analysis of flavor characteristics of peanut porridge using gas chromatography-ion mobility spectrometry combined with intelligent sensory technology

Evaluating chatbot architectures for public service delivery: balancing functionality, safety, ethics, and adaptability

The versatility of algae in addressing the global sustainability challenges