Defense Signaling Pathways | List of Frontiers open access articles

Original Research

Published on 05 Nov 2025

Identification and validation of paraptosis-related biomarkers in recurrent miscarriage

in Immunological Tolerance and Regulation

Yunhui Wan
Fang Fang
Qiao Wang
Jia Xu
Pei Zhu
Ying Cui
Lili Hou
Huimin Wang
Xiaoyong Chen

Frontiers in Immunology

doi 10.3389/fimmu.2025.1656650

321 views

Original Research

Published on 05 Nov 2025

The dynamic systemic immuno-inflammatory index: a novel predictor of neoadjuvant chemotherapy response and outcome in high-risk pediatric neuroblastoma

in Pediatric Oncology

Chenglong Zhang
Xiaoyu Wang
Huizhong Niu
Pengju Zhang
Jianlei Geng

Frontiers in Oncology

doi 10.3389/fonc.2025.1671233

133 views

Review

Published on 05 Nov 2025

Bone metastases in pheochromocytomas and paragangliomas: a narrative review of presentation, diagnosis and management

in Cancer Endocrinology

Jorge Eduardo Contreras-Saldarriaga
Melissa Loaiza-Alzate

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1671486

292 views

Review

Published on 05 Nov 2025

What is the need for adrenalectomy in patients with congenital adrenal hyperplasia in the era of CRF1/ACTH inhibitors?

in Adrenal Endocrinology

Olga Fedorova
Henrik Falhammar

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1693063

446 views

Review

Published on 05 Nov 2025

Gut-ovary axis in polycystic ovary syndrome: mechanistic insights and gut microbiota-targeted therapeutic strategies

in Translational and Clinical Endocrinology

Mei Zhao
Danlin Chen
Xiumei Hu
Caiping Xie
Lianwei Xu
Fuhua Zhou

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1684492

181 views

Original Research

Published on 05 Nov 2025

Artificial intelligence-based evaluation of prognostic benefits from immunotherapy plus targeted therapy with or without radiotherapy or TACE in advanced hepatocellular carcinoma

in Pharmacology of Anti-Cancer Drugs

Yuehong Deng
Shiqin Song
Huarong Zhao
Yuqian Yang
Simin Lu
Xueting Li

Frontiers in Oncology

doi 10.3389/fonc.2025.1694565

319 views

Case Report

Published on 05 Nov 2025

Case Report: A new noninvasive device-based treatment of a mesencephalic H3 K27M glioma

in Neuro-Oncology and Neurosurgical Oncology

Santosh A. Helekar
Omkar B. Ijare
Martyn A. Sharpe
Kumar Pichumani
David S. Baskin

Frontiers in Oncology

doi 10.3389/fonc.2025.1626516

376 views

Original Research

Published on 05 Nov 2025

Understanding the preference of online health information seeking among college students using the best-worst scaling method

in Public Health Education and Promotion

Dan Wang
Wang Jiang
Haihong Chen
Manli Chen
Guangwen Gong
Yansun Sun
Yajing Wu
Xuemei Wang
Xiping Li

Frontiers in Public Health

doi 10.3389/fpubh.2025.1670106

126 views

Systematic Review

Published on 05 Nov 2025

Tenecteplase versus alteplase in bridging therapy in patients with large vessel occlusion stroke: a meta-analysis

in Stroke

Xiaohan Zhang
Min Tao
Tian Wang
Rongxin He
Lingwan Yan
Xiaozuo Lin
Pingkai Wang
Yinan Zeng
Jipeng Yu
Hongxia Liu

Frontiers in Neurology

doi 10.3389/fneur.2025.1661357

166 views

Review

Published on 05 Nov 2025

The role of dysregulated copper metabolism in diabetes and its complications: a review

in Diabetes: Molecular Mechanisms

Chen Wang
Junhong Wu
Yan Wang
Chengcheng Huang
Mengjuan Wei
Yufei Zhang
Renchu Shen
Jingwu Wang

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1681001

367 views

Original Research

Published on 05 Nov 2025

Experience sharing of endoscopy-assisted total mastectomy with and without immediate breast reconstruction

in Surgical Oncology

Yidan Lin
Minxue Zhuang
Hongbin Qiu
Wei Chen
Yihui He
Huanhong Zeng
Mengbo Lin
Hui Zhang

Frontiers in Oncology

doi 10.3389/fonc.2025.1711540

309 views

Original Research

Published on 05 Nov 2025

Multicenter study on CT-based Radiomics for predicting severity and delayed recovery in Mycoplasma pneumoniae pneumonia

in Pulmonary Medicine

Qian Li
Zi-Jun Song
Wenjing Chen
Wenwen Yan

Frontiers in Medicine

doi 10.3389/fmed.2025.1652653

127 views

Original Research

Published on 05 Nov 2025

Eddy kinetic energy variability of the Kuroshio Extension and its upstream-downstream connectivity

in Physical Oceanography

SeungYong Lee
Hanna Na
Young-Gyu Park
Hyung-Ju Park
Suna Cho

Frontiers in Marine Science

doi 10.3389/fmars.2025.1648295

203 views

Original Research

Published on 05 Nov 2025

Rodent home cage monitoring for preclinical safety pharmacology assessment: results of a multi-company validation evaluating nonclinical and clinical data from three compounds

in Regulatory Toxicology

R. R. Sillito
J. Sutherland
A. Milne
C. Giuliano
C. Sigfridsson
M. Rolf
A. K. Cherian
M. McClafferty
E. I. Rossman
G. Teuns

Frontiers in Toxicology

doi 10.3389/ftox.2025.1655330

689 views

Systematic Review

Published on 05 Nov 2025

Hypertriglyceridemia is a dose-dependent risk factor for type 2 diabetes mellitus: a systematic review and meta-analysis

in Clinical Diabetes

Luca Havelda
Eszter Ágnes Szalai
Mahmoud Obeidat
Dalma Dobszai
Dániel Sándor Veres
Tamás Kói
Emese Sipter
Szilárd Váncsa
Péter Jenő Hegyi
Maria Bucur

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1710007

Systematic Review

Published on 05 Nov 2025

The effect of vitamin K2 supplementation on bone turnover biochemical markers in postmenopausal osteoporosis patients: a systematic review and meta-analysis

in Bone Research

Zechen Zhang
Yuyi Li
Jinkun Li
Yifeng Yuan
Kang Liu
Xiaolin Shi

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1703116

567 views

Articles

Identification and validation of paraptosis-related biomarkers in recurrent miscarriage

The dynamic systemic immuno-inflammatory index: a novel predictor of neoadjuvant chemotherapy response and outcome in high-risk pediatric neuroblastoma

Bone metastases in pheochromocytomas and paragangliomas: a narrative review of presentation, diagnosis and management

What is the need for adrenalectomy in patients with congenital adrenal hyperplasia in the era of CRF1/ACTH inhibitors?

Gut-ovary axis in polycystic ovary syndrome: mechanistic insights and gut microbiota-targeted therapeutic strategies

Artificial intelligence-based evaluation of prognostic benefits from immunotherapy plus targeted therapy with or without radiotherapy or TACE in advanced hepatocellular carcinoma

Case Report: A new noninvasive device-based treatment of a mesencephalic H3 K27M glioma

Understanding the preference of online health information seeking among college students using the best-worst scaling method

Tenecteplase versus alteplase in bridging therapy in patients with large vessel occlusion stroke: a meta-analysis

The role of dysregulated copper metabolism in diabetes and its complications: a review

Experience sharing of endoscopy-assisted total mastectomy with and without immediate breast reconstruction

Multicenter study on CT-based Radiomics for predicting severity and delayed recovery in Mycoplasma pneumoniae pneumonia

Eddy kinetic energy variability of the Kuroshio Extension and its upstream-downstream connectivity

Rodent home cage monitoring for preclinical safety pharmacology assessment: results of a multi-company validation evaluating nonclinical and clinical data from three compounds

Hypertriglyceridemia is a dose-dependent risk factor for type 2 diabetes mellitus: a systematic review and meta-analysis

The effect of vitamin K2 supplementation on bone turnover biochemical markers in postmenopausal osteoporosis patients: a systematic review and meta-analysis