Drug Design And Development | List of Frontiers open access articles

Original Research

Published on 03 Oct 2025

Analysis of key flavor compounds in commercial cherry wines by HS-SPME-GC-MS, HS-GC-IMS, and sensory evaluation

in Food Chemistry

Jiawei Qi
Jie Li
Zihan Liu
Xuemei Yang
Tingting Qi
Guoqin Wei
Juanxia Yang
Cheng Liu

Frontiers in Nutrition

doi 10.3389/fnut.2025.1631912

504 views

Systematic Review

Published on 03 Oct 2025

Prevalence of tuberculosis among People Who Use Drugs 2000–2024: a systematic review and meta-analysis

in Infectious Diseases: Epidemiology and Prevention

W. S. Ngowi
O. O. Mandizadza
Minyan Wang
W. T. Shao
Conghua Ji

Frontiers in Public Health

doi 10.3389/fpubh.2025.1635053

413 views

Original Research

Published on 03 Oct 2025

Associations between COVID-19 incidence and environmental stressors in Brazil: a nationwide study from 2020 to 2022

in Air Quality and Health

Leona Hoffmann
Ludmilla Viana Jacobson
Thilo Erbertseder
Moritz Berger
Jörn Rittweger
Rochelle Schneider

Frontiers in Environmental Health

doi 10.3389/fenvh.2025.1635503

313 views

Original Research

Published on 03 Oct 2025

Characterization of a sesquiterpene synthase and a short-chain dehydrogenase in zerumbone biosynthesis and the applications in engineered Saccharomyces cerevisiae

in Plant Metabolism and Chemodiversity

Mengdie Xu
Yimeng Xia
Gaowei Fang
Tangli Li
Jing Ma
Dengyu Li
Qiuhui Wei
Lichan Tu
Xiaopu Yin
Tianyuan Hu

Frontiers in Plant Science

doi 10.3389/fpls.2025.1635141

436 views

Original Research

Published on 03 Oct 2025

Milk fat globule membrane supplementation in formula modulates the gut microbiome and metabolic status of piglets and normalizes intestinal development

in Nutrition and Metabolism

Zonghan Zhou
Bin Liu
Jun Shen
Caihong Yan
Guang Yang
Yu Zhang
Junying Zhao
Lijun Chen

Frontiers in Nutrition

doi 10.3389/fnut.2025.1632519

622 views

Review

Published on 03 Oct 2025

Optimization of production strategies for African indigenous trees: a case study of tree growers and sellers of Dovyalis caffra (Kei apple) from Eastern Cape of South Africa

in Food Characterization

M. Mfini
C. P. Laubscher
H. Witbooi

Frontiers in Food Science and Technology

doi 10.3389/frfst.2025.1631026

392 views

Correction

Published on 03 Oct 2025

Correction: Upregulation of long noncoding RNA GCC2-AS1 facilitates malignant phenotypes and correlated with unfavorable prognosis for lung adenocarcinoma

in Thoracic Oncology

Fengqiang Yu
Mingqiang Liang
Weidong Wu
Yu Huang
Jiantao Zheng
Bin Zheng
Chun Chen

Frontiers in Oncology

doi 10.3389/fonc.2025.1644707

186 views

Original Research

Published on 03 Oct 2025

Effects of dietary supplementation with hydroponic wheat seedlings on rumen fermentation, meat quality, amino acid and fatty acid contents, and rumen bacterial diversity in sheep

in Microorganisms in Vertebrate Digestive Systems

Yong Tuo
Jinlong Li
Guzalnur Amat
Zhiqiang Cheng
Liangzhong Hou
Changjiang Zang
Tongjun Guo

Frontiers in Microbiology

doi 10.3389/fmicb.2025.1657777

1,210 views

Original Research

Published on 03 Oct 2025

Understanding older adults’ adoption of smart product-service systems for medication management in China: an extended UTAUT model approach

in Aging and Public Health

Ruochen Fu
Xiaofei Ma

Frontiers in Public Health

doi 10.3389/fpubh.2025.1657473

441 views

Case Report

Published on 03 Oct 2025

Case Report: Dual molecular diagnosis of gain-of-function STAT1 mutation and regulatory STAT3 variant in a patient with a hyper-IgE-like phenotype

in Primary Immunodeficiencies

Roukaya Yaakoubi
Najla Mekki
Amel Ben Chehida
Ansem Benhammadi
Koon-Wing Chan
Daniel Leung
Charfeddine Gharsallah
Fatma Zahra Guerfali
Mohamed-Ridha Barbouche
Yu Lung Lau

Frontiers in Immunology

doi 10.3389/fimmu.2025.1646761

1,514 views

Review

Published on 03 Oct 2025

Curcumin for the treatment of pituitary adenomas: the potential of a single agent for multifaceted therapeutic effects

in Pituitary Endocrinology

Zisheng Yan
Chen Liang
Fujia Nian
Gang Peng
Yuntao Li
Jingyu Guan
Ruihan Pan
Gaochao Song

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1648521

816 views

Original Research

Published on 03 Oct 2025

Study on the influencing factors of the first-line treatment response to primary immune thrombocytopenia in children

in Pediatric Hematology and Hematological Malignancies

Bihan Zhang
Qian Hu
Qiaodao Wu
Jianying Ning

Frontiers in Pediatrics

doi 10.3389/fped.2025.1679463

569 views

Original Research

Published on 03 Oct 2025

Effects of a novel fulvic acid-enriched water-soluble fertilizer on potato growth, yield, and water-fertilizer use efficiency under different drip irrigation regimes

in Crop and Product Physiology

Fulin Xu
Yi Liu
Jiangtao Li
Jinquan Zhu
Nan Wu
Ajing Meng

Frontiers in Plant Science

doi 10.3389/fpls.2025.1672560

1,358 views

Original Research

Published on 03 Oct 2025

Association of preoperative systemic inflammation with postoperative conduction block in TAVI patients

in Intensive Care Cardiovascular Medicine

Ying-Lu Shi
Dong-Sheng Di
Cheng-Xin Zhang
Wen-Hui Gong
Sheng-Lin Ge

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2025.1671841

290 views

Original Research

Published on 03 Oct 2025

From implementation to discontinuation: multi-year experience with the multiple sclerosis performance test as a digital monitoring tool

in Human Factors and Digital Health

Dirk Schriefer
Anja Dillenseger
Yassin Atta
Hernan Inojosa
Tjalf Ziemssen

Frontiers in Digital Health

doi 10.3389/fdgth.2025.1672732

544 views

Original Research

Published on 03 Oct 2025

Empowering college students to select ideal advisors: a text-based recommendation model

in Digital Learning Innovations

Xinmin Wang
Jiaxin Zhou
Ling Jian
Yue Yin
Li Li

Frontiers in Education

doi 10.3389/feduc.2025.1673956

231 views

Articles

Analysis of key flavor compounds in commercial cherry wines by HS-SPME-GC-MS, HS-GC-IMS, and sensory evaluation

Prevalence of tuberculosis among People Who Use Drugs 2000–2024: a systematic review and meta-analysis

Associations between COVID-19 incidence and environmental stressors in Brazil: a nationwide study from 2020 to 2022

Characterization of a sesquiterpene synthase and a short-chain dehydrogenase in zerumbone biosynthesis and the applications in engineered Saccharomyces cerevisiae

Milk fat globule membrane supplementation in formula modulates the gut microbiome and metabolic status of piglets and normalizes intestinal development

Optimization of production strategies for African indigenous trees: a case study of tree growers and sellers of Dovyalis caffra (Kei apple) from Eastern Cape of South Africa

Correction: Upregulation of long noncoding RNA GCC2-AS1 facilitates malignant phenotypes and correlated with unfavorable prognosis for lung adenocarcinoma

Effects of dietary supplementation with hydroponic wheat seedlings on rumen fermentation, meat quality, amino acid and fatty acid contents, and rumen bacterial diversity in sheep

Understanding older adults’ adoption of smart product-service systems for medication management in China: an extended UTAUT model approach

Case Report: Dual molecular diagnosis of gain-of-function STAT1 mutation and regulatory STAT3 variant in a patient with a hyper-IgE-like phenotype

Curcumin for the treatment of pituitary adenomas: the potential of a single agent for multifaceted therapeutic effects

Study on the influencing factors of the first-line treatment response to primary immune thrombocytopenia in children

Effects of a novel fulvic acid-enriched water-soluble fertilizer on potato growth, yield, and water-fertilizer use efficiency under different drip irrigation regimes

Association of preoperative systemic inflammation with postoperative conduction block in TAVI patients

From implementation to discontinuation: multi-year experience with the multiple sclerosis performance test as a digital monitoring tool

Empowering college students to select ideal advisors: a text-based recommendation model