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CORRECTION article

Front. Oncol., 03 October 2025

Sec. Thoracic Oncology

Volume 15 - 2025 | https://doi.org/10.3389/fonc.2025.1644707

Correction: Upregulation of long noncoding RNA GCC2-AS1 facilitates malignant phenotypes and correlated with unfavorable prognosis for lung adenocarcinoma

This article is a correction to:

  1. Upregulation of Long Non-Coding RNA GCC2-AS1 Facilitates Malignant Phenotypes and Correlated With Unfavorable Prognosis for Lung Adenocarcinoma

    1. Read original article
Fengqiang Yu,&#x;Fengqiang Yu1,2†Mingqiang Liang,&#x;Mingqiang Liang1,2†Weidong Wu,Weidong Wu1,2Yu HuangYu Huang1Jiantao ZhengJiantao Zheng1Bin ZhengBin Zheng1Chun Chen,*Chun Chen1,2*
  • 1Department of Thoracic Surgery, Fujian Medical University Union Hospital, Fuzhou, China
  • 2Fujian Provincial Key Laboratory of Cardiothoracic Surgery, Fujian Medical University Union Hospital, Fuzhou, China

A Correction on
Upregulation of long noncoding RNA GCC2-AS1 facilitates malignant phenotypes and correlated with unfavorable prognosis for lung adenocarcinoma

By Yu F, Liang M, Wu W, Huang Y, Zheng J, Zheng B and Chen C (2021). Front. Oncol. 10:628608. doi: 10.3389/fonc.2020.628608

There was a mistake in Figure 3C as published. Figure 3C inadvertently contained incorrect images in the transwell assays of A549 cell lines (left and right) due to an oversight in the processing of a substantial volume of images. The corrected Figure 3 appears below.

Figure 3
Graphical representation of experiments with A549 and H292 cells. Panel A shows bar charts of GCC2-AS1 expression levels, with significant reductions when silenced (si-GCC2-AS1). Panel B presents line graphs of cell proliferation over time, indicating decreased growth in silenced cells. Panel C includes images of cell invasion assays and corresponding bar graphs, showing reduced invasion in silenced cells. Statistical significance is marked with asterisks.

Figure 3. Effects of GCC2-AS1 on lung adenocarcinoma cells. (A) Relative expression of GCC2-AS1 in A549 and H292 cells transfected with GCC2-AS1 siRNA and negative control. (B) CCK8 assays was performed to detected the proliferation rate. (C) Transwell assays were assessed the invasive ability of each group. Scale bar, 20 μm. Data are presented as the mean ± SD of three independent experiments (**P < 0.01; ***P < 0.001).

The original version of this article has been updated.

Publisher’s note

All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article, or claim that may be made by its manufacturer, is not guaranteed or endorsed by the publisher.

Keywords: lncRNA, GCC2-AS1, lung adenocarcinoma, The Cancer Genome Atlas, prognosis

Citation: Yu F, Liang M, Wu W, Huang Y, Zheng J, Zheng B and Chen C (2025) Correction: Upregulation of long noncoding RNA GCC2-AS1 facilitates malignant phenotypes and correlated with unfavorable prognosis for lung adenocarcinoma. Front. Oncol. 15:1644707. doi: 10.3389/fonc.2025.1644707

Received: 10 June 2025; Accepted: 23 September 2025;
Published: 03 October 2025.

Approved by:

Frontiers Editorial Office, Frontiers Media SA, Switzerland

Copyright © 2025 Yu, Liang, Wu, Huang, Zheng, Zheng and Chen. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

*Correspondence: Chun Chen, Y2hlbmNodW4wMjA5QDE2My5jb20=

†These authors have contributed equally to this work

Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.