Drug Free | List of Frontiers open access articles

Original Research

Published on 28 Nov 2025

Nano-elicitation strategy to improve specialized metabolite pathways in plant cell suspension culture

in Plant Biotechnology

Kamran Ashraf
Qamar uz Zaman
Weihua Tang
Pei Jiang
Xun Wan
Khitev Yuri
Ali Mohsin
Meijin Guo

Frontiers in Plant Science

doi 10.3389/fpls.2025.1679901

475 views

Review

Published on 28 Nov 2025

Fertility in congenital adrenal hyperplasia due to 21-hydroxylase deficiency: a review

in Reproduction

Zuzanna Roszkowska
Małgorzata Bobrowicz
Joanna Betlejewska
Joanna Hubska
Beata Rak-Makowska
Urszula Ambroziak

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1682341

252 views

Original Research

Published on 28 Nov 2025

Characteristic brain function and network activity patterns in adolescent first-episode depression: a resting-state functional magnetic resonance imaging study

in Neuroimaging for Cognitive Neuroscience

Liulu Zhang
Pingping Jie
Jie Zhao
Yuting Fu
Yong Liu
Bo Xiang
Jun Lv
Weidan Luo

Frontiers in Neuroimaging

doi 10.3389/fnimg.2025.1677410

125 views

Original Research

Published on 28 Nov 2025

Prediction of acupuncture efficacy in acute ischemic stroke constructing a clinical-radiomics multimodal model

in Experimental Therapeutics

Lijuan Zhao
Ziguang Huang
Baoying Zhao
Ran An
Yanyan Cheng

Frontiers in Neurology

doi 10.3389/fneur.2025.1682842

182 views

Perspective

Published on 28 Nov 2025

Restoring trust in vaccination: listening to patients and acknowledging Post-Acute COVID Vaccine Syndrome

in Translational Medicine

Matthew Halma
Joseph Varon

Frontiers in Medicine

doi 10.3389/fmed.2025.1688170

1,796 views

Original Research

Published on 28 Nov 2025

Does the free trade zone promote green technological innovation?—evidence from the perspective of industrial agglomeration and digital economy in 285 cities in China

in Cities in the Global South

Henan Zhang
Shangyue Jia
Binyu Ren
Hongling Ge

Frontiers in Sustainable Cities

doi 10.3389/frsc.2025.1652437

294 views

Original Research

Published on 28 Nov 2025

Plasma-derived exosomal miRNAs as potentially novel biomarkers for type 2 diabetes mellitus with abdominal obesity

in Clinical Diabetes

Yan Li
Youqin Wang
Zhan Li
Lihui Feng
Ru Feng
Jia Jia
Li Xing
Lu Zheng

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1656132

206 views

Original Research

Published on 28 Nov 2025

Different structuring factors and distribution patterns of marine prokaryotic and eukaryotic communities in the subtropical Kuroshio region

in Marine Ecosystem Ecology

Youta Sugai
Masayuki Ushio
Junya Hirai
Masumi Hasegawa-Takano
Takayoshi Fujiwara
Mako Takada
Kaho Mori
Hideki Fukuda
Hiroaki Saito
Koji Hamasaki

Frontiers in Marine Science

doi 10.3389/fmars.2025.1656531

504 views

Original Research

Published on 28 Nov 2025

Baseline PET/CT metabolic parameters in the double-expressor subtype of diffuse large B-cell lymphoma: development of a clinical–radiologic–pathologic predictive model

in Cancer Imaging and Image-directed Interventions

Jingjing Liang
Guoxiu Lu
Qi Peng
Jigang Wang
Guoxu Zhang

Frontiers in Oncology

doi 10.3389/fonc.2025.1660516

185 views

Original Research

Published on 28 Nov 2025

Childhood emotional abuse and suicidal ideation in college students: exploring the mediating role of alexithymia and the moderating effect of physical exercise

in Public Mental Health

Chang Hu
Wenying Huang
Wen Zhang

Frontiers in Psychiatry

doi 10.3389/fpsyt.2025.1660164

275 views

Review

Published on 28 Nov 2025

Decoding the exosomal secretome: stem cell-elicted microenvironmental reprogramming for anterior cruciate ligament regenerative medicine

in Tissue Engineering and Regenerative Medicine

Junjie Chen
Jiayang He
Dujiang Yang
Yuhan He
Yuhao Wei
Zhiqiang Zhang
Xue Zhou
Ming Cheng

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1691651

502 views

Original Research

Published on 28 Nov 2025

Restorative perceptions of migratory elderly: insights for inclusive urban park design in china

in Environmental Psychology

Yurui Chen
Shureen Faris Abdul Shukor
Suhardi Maulan
Adam Aruldewan S. Muthuveeran

Frontiers in Psychology

doi 10.3389/fpsyg.2025.1695092

791 views

Perspective

Published on 28 Nov 2025

Therapeutic potential of peptidomimetics of suppressors of cytokine signaling (SOCS) proteins in rheumatic disorders

in Rheumatology

Alessia Cugudda
Daniela Marasco

Frontiers in Medicine

doi 10.3389/fmed.2025.1708293

129 views

Original Research

Published on 28 Nov 2025

Training in-service subject teachers to implement formative assessment through action research

in Teacher Education

Davide Parmigiani
Elisabetta Nicchia
Myrna Pario
Emiliana Murgia
Slaviša Radović
Marcea Ingersoll

Frontiers in Education

doi 10.3389/feduc.2025.1695771

254 views

Systematic Review

Published on 28 Nov 2025

Presurgical molecular therapy for renal cell carcinoma with venous tumor thrombus: a systematic review and meta-analysis

in Cancer Immunity and Immunotherapy

Kewei Chen
Lin Zhuo
Zhuo Liu
Liyuan Ge
Le Yu
Shudong Zhang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1705494

291 views

Original Research

Published on 28 Nov 2025

Modifying the engineering properties of naturally occurring bitumen for sustainable pavement construction

in Construction Materials

Roland Tolulope Loto
Ayobmi Busari
Helen Babalola
Oluwatosin Dada

Frontiers in Built Environment

doi 10.3389/fbuil.2025.1704316

198 views

Articles

Nano-elicitation strategy to improve specialized metabolite pathways in plant cell suspension culture

Fertility in congenital adrenal hyperplasia due to 21-hydroxylase deficiency: a review

Characteristic brain function and network activity patterns in adolescent first-episode depression: a resting-state functional magnetic resonance imaging study

Prediction of acupuncture efficacy in acute ischemic stroke constructing a clinical-radiomics multimodal model

Restoring trust in vaccination: listening to patients and acknowledging Post-Acute COVID Vaccine Syndrome

Does the free trade zone promote green technological innovation?—evidence from the perspective of industrial agglomeration and digital economy in 285 cities in China

Plasma-derived exosomal miRNAs as potentially novel biomarkers for type 2 diabetes mellitus with abdominal obesity

Different structuring factors and distribution patterns of marine prokaryotic and eukaryotic communities in the subtropical Kuroshio region

Baseline PET/CT metabolic parameters in the double-expressor subtype of diffuse large B-cell lymphoma: development of a clinical–radiologic–pathologic predictive model

Childhood emotional abuse and suicidal ideation in college students: exploring the mediating role of alexithymia and the moderating effect of physical exercise

Decoding the exosomal secretome: stem cell-elicted microenvironmental reprogramming for anterior cruciate ligament regenerative medicine

Restorative perceptions of migratory elderly: insights for inclusive urban park design in china

Therapeutic potential of peptidomimetics of suppressors of cytokine signaling (SOCS) proteins in rheumatic disorders

Training in-service subject teachers to implement formative assessment through action research

Presurgical molecular therapy for renal cell carcinoma with venous tumor thrombus: a systematic review and meta-analysis

Modifying the engineering properties of naturally occurring bitumen for sustainable pavement construction