Frontal Areas | List of Frontiers open access articles

Original Research

Published on 25 Nov 2025

Doxorubicin induces cardiotoxicity by enhancing autophagy via mTOR signaling in hiPSC- and hESC-derived cardiomyocytes

in Stem Cell Research

Minxia Ke
Hao Wang
Kailun Yang
Meng Ji
Nianmin Qi
Yuehong Wu

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1616235

375 views

Original Research

Published on 25 Nov 2025

Deep learning-based survival analysis of bladder cancer patients in the Putuo District, Shanghai, China

in Genitourinary Oncology

Wang Ruojing
Shen Yuan
Shi Feiya
Yang Lijuan
Qin Yicen

Frontiers in Oncology

doi 10.3389/fonc.2025.1619309

233 views

Mini Review

Published on 25 Nov 2025

Mechanisms of synovial macrophage polarization in osteoarthritis pathogenesis and their therapeutic implications

in Systems Immunology

Kun Zhang
Zheng Wang
Jiaqi He
Liuru Lu
Wenshu Wang
Aiwei Yang
Huayi Xie
Linhui Huang
Yuying Huang
Ke Zhang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1637731

467 views

Hypothesis and Theory

Published on 25 Nov 2025

Applying self-determination theory to behavior change technologies: insights from two projects in the health domain

in Sport Psychology

Rebecca Gerstenberg
Emil Rosenlund Høeg
Jolene Van der Kaap-Deeder
Marc Hassenzahl

Frontiers in Psychology

doi 10.3389/fpsyg.2025.1634267

905 views

Original Research

Published on 25 Nov 2025

Interpretable machine learning model for predicting covert hepatic encephalopathy in patients with cirrhosis: a multicenter study

in Precision Medicine

Yilong Liu
Kai Ding
Yifan Qiu
Peiqin Wang
Ruoyao Wang
Xin Zeng
Chuan Yin

Frontiers in Medicine

doi 10.3389/fmed.2025.1686005

384 views

Original Research

Published on 25 Nov 2025

Relationship between thyroid nodules and iodine nutritional status, thyroglobulin (Tg), and other influencing factors: a 1:1 matched case-control study

in Thyroid Endocrinology

Qingying Lin
Lijin Wang
Diqun Chen
Jiani Wu
Ying Lan
Qingdong Jin
Yanqing Chen
Zhihui Chen
Muhua Wang

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1685719

243 views

Study Protocol

Published on 25 Nov 2025

Opposing needling in the treatment of knee osteoarthritis: an improved study protocol for a randomized controlled trial

in Rheumatology

Huiying Li
Siyu Qian
Yanqin Liu
Yan Guo
Xiaoqin Chen
Yao Hu
Qiyue Fu
Qing Li
Yuting Xiang
Ying Liu

Frontiers in Medicine

doi 10.3389/fmed.2025.1698983

176 views

Original Research

Published on 25 Nov 2025

The nexus of soil fertility, bioconcentration and soil pollution load in the tropical land use systems of Western Ghana

in Soil Pollution & Remediation

Meryem El Mellouki
Ali Boularbah
Fassil Kebede

Frontiers in Soil Science

doi 10.3389/fsoil.2025.1703751

376 views

Review

Published on 25 Nov 2025

In-silico pharmacological insights into the therapeutic potential of microRNAs for microplastic-associated cancers

in Cancer Cell Biology

Akmaral Baspakova
Afshin Zare
Nadiar M. Mussin
Nader Tanideh
Kulyash R. Zhilisbayeva
Ramazon Safarzoda Sharoffidin
Roza Suleimenova
Gulden Yelgondina
Akmeiir E. Kaliyeva
Aigerim A. Umbetova

Frontiers in Cell and Developmental Biology

doi 10.3389/fcell.2025.1699693

324 views

Review

Published on 25 Nov 2025

The research progress of LACC1

in Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

Feng Li
Xinyi Cui
Qingli Yang
Yu Nie
Jinchun Wang
Shibo Sun

Frontiers in Immunology

doi 10.3389/fimmu.2025.1698702

241 views

Brief Research Report

Published on 25 Nov 2025

Mechanism of exogenous enzymes participation in the regulation of digestion and metabolism in model chickens

in Animal Nutrition and Metabolism

Vladimir Vertiprakhov
Bayarma S. Dashieva
Alexei M. Grigoriev
Veronika D. Ashikhmina

Frontiers in Veterinary Science

doi 10.3389/fvets.2025.1701604

338 views

Original Research

Published on 25 Nov 2025

Beyond prescriptions: chronic medication adherence predicts mortality risk in a large-scale cohort study

in Drugs Outcomes Research and Policies

Jessica Hamuy Blanco
Dina C. Janse van Rensburg
Audrey Jansen van Rensburg
Corrie Uys
Natalie Schellack

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1701588

253 views

Original Research

Published on 25 Nov 2025

Creativity and writing with generative artificial intelligence in the master’s degree in teacher training

in Digital Education

José Rovira-Collado
Sebastián Miras
Copelia Mateo-Guillen
Mónica Ruiz-Bañuls

Frontiers in Education

doi 10.3389/feduc.2025.1700268

743 views

Mini Review

Published on 25 Nov 2025

Type I interferons in inflammatory bowel diseases: balancing barrier integrity, repair and inflammation in the intestinal epithelium

in Precision Medicine

Mikayla R. King
Roslyn A. Kemp
Safina Gadeock

Frontiers in Medicine

doi 10.3389/fmed.2025.1713424

194 views

Original Research

Published on 25 Nov 2025

Impact of mineral fertilization and Trichoderma application on soil microbiota of young olive trees inoculated with Verticillium dahliae

in Terrestrial Microbiology

Guillem Segarra
Marc Sancho-Adamson
M. Isabel Trillas
Joan Romanyà

Frontiers in Microbiology

doi 10.3389/fmicb.2025.1708981

506 views

Mini Review

Published on 25 Nov 2025

Traditional Chinese medicine monomers: a new strategy against diabetic kidney disease by regulating cholesterol efflux

in Nutrition and Metabolism

Chenguang Wu
Jianing Sun
Junwei Shi
Zhe Li
Yan An
Han Zhu
Lifan Wang
Peng Liu

Frontiers in Nutrition

doi 10.3389/fnut.2025.1708809

349 views

Articles

Doxorubicin induces cardiotoxicity by enhancing autophagy via mTOR signaling in hiPSC- and hESC-derived cardiomyocytes

Deep learning-based survival analysis of bladder cancer patients in the Putuo District, Shanghai, China

Mechanisms of synovial macrophage polarization in osteoarthritis pathogenesis and their therapeutic implications

Applying self-determination theory to behavior change technologies: insights from two projects in the health domain

Interpretable machine learning model for predicting covert hepatic encephalopathy in patients with cirrhosis: a multicenter study

Relationship between thyroid nodules and iodine nutritional status, thyroglobulin (Tg), and other influencing factors: a 1:1 matched case-control study

Opposing needling in the treatment of knee osteoarthritis: an improved study protocol for a randomized controlled trial

The nexus of soil fertility, bioconcentration and soil pollution load in the tropical land use systems of Western Ghana

In-silico pharmacological insights into the therapeutic potential of microRNAs for microplastic-associated cancers

The research progress of LACC1

Mechanism of exogenous enzymes participation in the regulation of digestion and metabolism in model chickens

Beyond prescriptions: chronic medication adherence predicts mortality risk in a large-scale cohort study

Creativity and writing with generative artificial intelligence in the master’s degree in teacher training

Type I interferons in inflammatory bowel diseases: balancing barrier integrity, repair and inflammation in the intestinal epithelium

Impact of mineral fertilization and Trichoderma application on soil microbiota of young olive trees inoculated with Verticillium dahliae

Traditional Chinese medicine monomers: a new strategy against diabetic kidney disease by regulating cholesterol efflux