Frontal Areas | List of Frontiers open access articles

Mini Review

Published on 25 Nov 2025

Mechanisms of synovial macrophage polarization in osteoarthritis pathogenesis and their therapeutic implications

in Systems Immunology

Kun Zhang
Zheng Wang
Jiaqi He
Liuru Lu
Wenshu Wang
Aiwei Yang
Huayi Xie
Linhui Huang
Yuying Huang
Ke Zhang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1637731

503 views

Original Research

Published on 25 Nov 2025

Development of a standardized ovine aortic stenosis model: a pathomimetic platform for TAVI evaluation and durability testing

in Heart Valve Disease

Yan Zhu
Nana Qin
Jie Hou
Baoyin Li
Fangxu Liu
Xin Jiang
Zhuo Chen
Xiongtao Lin
Xiaohang Tong
Xufeng Wei

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2025.1663130

257 views

Original Research

Published on 25 Nov 2025

ER stress in D1-MSNs mediates cocaine-induced behavioral plasticity via the ATF4–SPTLC1 axis

in Neuropharmacology

Yue Zhao
Shu Li
Linhong Jiang
Ying Zhao
Weihong Kuang
Qingfan Wei
Yuanyi Zhou
Shuang Han
Liang Wang
Hongchun Li

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1677343

268 views

Original Research

Published on 25 Nov 2025

Effect of general anesthesia vs. local anesthesia and collateral status on outcomes in anterior circulation occlusion

in Stroke

Guojie Chen
Rundong Chen
Tianxiang Gao
Lijun Wang
Hongye Xu
Wen Yin
Yu Gao
Lei Zhang
Yongxin Zhang
Pengfei Xing

Frontiers in Neurology

doi 10.3389/fneur.2025.1665185

315 views

Study Protocol

Published on 25 Nov 2025

An exploratory single arm study to evaluate the role of an Ayurvedic treatment protocol as a prerequisite for in vitro fertilization in women with diminished ovarian reserve incorporating multi-omics approaches: study protocol

in Family Medicine and Primary Care

Anjaly Muraleedharan
Avani Pillai
Bipin G. Nair
Hemavathi Shivapura Krishnarajabhatt
Chithra Ramachandran
Anjana Aji
Muralidharan Vanuopadath

Frontiers in Medicine

doi 10.3389/fmed.2025.1666888

511 views

Hypothesis and Theory

Published on 25 Nov 2025

Drug-targeted endoscopic submucosal dissection: a hypothetical framework toward non-electromechanical mucosal resection

in Gastroenterology

Conghua Song
Huiyuan Xu
Xiaomei Li

Frontiers in Medicine

doi 10.3389/fmed.2025.1668295

163 views

Original Research

Published on 25 Nov 2025

Disruption of global brain network topology in amnestic MCI: evidence from multimodal DTI and fMRI

in Brain Imaging Methods

Yingmei Han
Xue Bai
Weiqing Li
Ze Feng
Bingyuan Chu
Ming Yang
Qingqing Shang
Hanxi Zhang
Xinlu Li
Feng Wang

Frontiers in Neuroscience

doi 10.3389/fnins.2025.1675610

554 views

Original Research

Published on 25 Nov 2025

Association between the age-to-serum albumin ratio and all-cause mortality in patients with acute myocardial infarction: a retrospective cohort study

in Coronary Artery Disease

Xue-Cheng Song
Yong Xia
Qiang Feng
Yong-Ming He

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2025.1667312

223 views

Original Research

Published on 25 Nov 2025

Comparison of HIV/AIDS death estimates for 2019 between GBD 2019 and WHO mortality databases

in Infectious Diseases: Epidemiology and Prevention

Xuemei Wei
Fang Qin
Juan Li
Ya Huang
Shaopeng Lu
Junjie Huang
Lu Wang
Jie Li
Yukai Zhang
Xiaoxiang Yang

Frontiers in Public Health

doi 10.3389/fpubh.2025.1669277

311 views

Original Research

Published on 25 Nov 2025

Construction of a diagnostic prediction model for ischemic stroke using lactylation-related genes

in Brain Disease Mechanisms

Jierong Mo
Deyuan Ning
Shuyi Chen
Tianen Zhou
Peiyi Liu
Zhiquan Li
Wenmin Tang
Lianshan Guo
Zhiyong Lin
Ran Zhan

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2025.1672374

342 views

Brief Research Report

Published on 25 Nov 2025

Corrosion inhibition of an aluminum alloy by environmentally derived microbial biofilms

in Environmental Microbiomes

Zachary T. Burton
Han Liu
Nathan Stumme
Scott K. Shaw
Steven Harris
Simon Laflamme
Kaoru Ikuma

Frontiers in Microbiomes

doi 10.3389/frmbi.2025.1675064

352 views

Clinical Trial

Published on 25 Nov 2025

Clinical efficacy and metabolomics profiling of dachaihu decoction for patients with septic liver injury: a randomized controlled trial

in Ethnopharmacology

Zhen Yang
Xingyu Kao
Tianwei Zhu
Junna Lei
Na Huang
Jingli Chen
Mingfeng He
Qi Tang
Zhangrong Liang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1671732

272 views

Original Research

Published on 25 Nov 2025

Machine learning-based dynamic risk measurement for white sugar futures under geopolitical risks

in Social Physics

Zihao Qiu
Siyu Chen
Zixin Feng
Ruitong Luo
Zhiwei Wang

Frontiers in Physics

doi 10.3389/fphy.2025.1674717

301 views

Original Research

Published on 25 Nov 2025

Deep learning-based survival analysis of bladder cancer patients in the Putuo District, Shanghai, China

in Genitourinary Oncology

Wang Ruojing
Shen Yuan
Shi Feiya
Yang Lijuan
Qin Yicen

Frontiers in Oncology

doi 10.3389/fonc.2025.1619309

265 views

Original Research

Published on 25 Nov 2025

L-shaped association of triglyceride glucose-body mass index and self-rated mental health among the middle-aged and older adults: a national cohort study in China

in Aging and Public Health

Yanqin Li
Qi Gao
Fan Luo
Yuxin Lin
Ruqi Xu
Pingping Li
Yuping Zhang
Jiao Liu
Hongrui Zhan
Licong Su

Frontiers in Public Health

doi 10.3389/fpubh.2025.1672881

311 views

Original Research

Published on 25 Nov 2025

Explainable machine learning to predict postoperative ileus after radical cystectomy: an 11-year real-world cohort

in Medicine and Public Health

Xiaoping Chen
Guolong Chen
Zongxin Zheng
Huiming Lu
Yuyi Luo
Lu Man
Mengxiao Jiang

Frontiers in Artificial Intelligence

doi 10.3389/frai.2025.1678292

304 views

Articles

Mechanisms of synovial macrophage polarization in osteoarthritis pathogenesis and their therapeutic implications

Development of a standardized ovine aortic stenosis model: a pathomimetic platform for TAVI evaluation and durability testing

ER stress in D1-MSNs mediates cocaine-induced behavioral plasticity via the ATF4–SPTLC1 axis

Effect of general anesthesia vs. local anesthesia and collateral status on outcomes in anterior circulation occlusion

An exploratory single arm study to evaluate the role of an Ayurvedic treatment protocol as a prerequisite for in vitro fertilization in women with diminished ovarian reserve incorporating multi-omics approaches: study protocol

Drug-targeted endoscopic submucosal dissection: a hypothetical framework toward non-electromechanical mucosal resection

Disruption of global brain network topology in amnestic MCI: evidence from multimodal DTI and fMRI

Association between the age-to-serum albumin ratio and all-cause mortality in patients with acute myocardial infarction: a retrospective cohort study

Comparison of HIV/AIDS death estimates for 2019 between GBD 2019 and WHO mortality databases

Construction of a diagnostic prediction model for ischemic stroke using lactylation-related genes

Corrosion inhibition of an aluminum alloy by environmentally derived microbial biofilms

Clinical efficacy and metabolomics profiling of dachaihu decoction for patients with septic liver injury: a randomized controlled trial

Machine learning-based dynamic risk measurement for white sugar futures under geopolitical risks

Deep learning-based survival analysis of bladder cancer patients in the Putuo District, Shanghai, China

L-shaped association of triglyceride glucose-body mass index and self-rated mental health among the middle-aged and older adults: a national cohort study in China

Explainable machine learning to predict postoperative ileus after radical cystectomy: an 11-year real-world cohort