Isovolumetric Relaxation Time | List of Frontiers open access articles

Original Research

Published on 07 Nov 2025

Ginkgolide C alleviates atherosclerosis by activating LAMP-2A to enhance chaperone-mediated autophagy and promote NLRP3 inflammasome degradation

in Ethnopharmacology

Rui Zhang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1658725

500 views

Review

Published on 07 Nov 2025

Pathways and challenges in the clinical translational of radiopharmaceuticals for pediatric investigations

in Nuclear Medicine

Erik Stauff
Hanieh Karimi
Heidi H. Kecskemethy
Thomas H. Shaffer
Reza Vali
Lauren W. Averill
Xuyi Yue

Frontiers in Medicine

doi 10.3389/fmed.2025.1658588

834 views

Original Research

Published on 07 Nov 2025

Prognostic value of kappa free light chain index in patients with primary progressive multiple sclerosis

in Multiple Sclerosis and Neuroimmunology

Martin Schmidauer
Klaus Berek
Michael Auer
Gabriel Bsteh
Paola Cavalla
Franziska Di Pauli
Massimiliano Di Filippo
Florian Deisenhammer
Andreja Emeršič
Fabian Föttinger

Frontiers in Immunology

doi 10.3389/fimmu.2025.1658182

962 views

Case Report

Published on 07 Nov 2025

Exophytic colonic carcinoma complicated by gastrocolic fistula mimicking a giant gastric mass: a case report and brief review

in Surgical Oncology

Xiaofeng Deng
Zequn Zhang

Frontiers in Oncology

doi 10.3389/fonc.2025.1655501

536 views

Review

Published on 07 Nov 2025

Iron oxide nanoparticles empowering melanoma therapy: advances in multifunctional platform research

in Nanobiotechnology

Xiaolong Bai
Zhijun Wang
Ziyi Cao
Junping Zhen

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1655677

763 views

Original Research

Published on 07 Nov 2025

Relationship between heart rate variability and inflammation induced by physical exercise in a sedentary healthy population

in Exercise Physiology

David Ramiro-Cortijo
Santiago Ruvira
Ricardo Alonso de Celada
Elena Muñoz-Gómez
Silvia Cañas
Jose Magalhães
Silvia M. Arribas

Frontiers in Physiology

doi 10.3389/fphys.2025.1657812

1,444 views

Mini Review

Published on 07 Nov 2025

From hormonal immunomodulation to glioblastoma therapy: the emerging role of Ouabain

in Cancer Immunity and Immunotherapy

Arthur Gomes de Andrade
Deyse Cristina Madruga Carvalho
Daniel Wilson Arruda Magalhaes
Aline Cavalcanti de Queiroz
Magna Suzana Alexandre-Moreira
Sandra Rodrigues-Mascarenas
Luiz Henrique Agra Cavalcante-Silva

Frontiers in Immunology

doi 10.3389/fimmu.2025.1657671

661 views

Original Research

Published on 07 Nov 2025

A retrospective analysis of small molecule targeting inhibitor usage for lung cancer among outpatients in six major regions of China (2016–2022)

in Pharmacology of Anti-Cancer Drugs

Bo Chen
Chen Wang
Li-Ying Chen
Yan Hu
Yu-Zhen Wang
Liu-Cheng Li
Kai-Li Mao
Qiu Jiang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1700389

708 views

Original Research

Published on 07 Nov 2025

L2 growth mindset in AI-mediated language learning: effects of perceived usability and presence of generative AI chatbots

in Educational Psychology

Yanbin Huang
Huanhui Chen
Changyue Hu

Frontiers in Psychology

doi 10.3389/fpsyg.2025.1700117

1,825 views

Case Report

Published on 07 Nov 2025

Immune checkpoint inhibitor-induced diabetes can potentially be effectively treated with infliximab: a case report of two patients

in Clinical Diabetes

Noam Savion Gaiger
Michael E. Hurwitz
Navid Hafez
Harriet M. Kluger
Kevan C. Herold
Ana Luisa Perdigoto

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1697724

678 views

Mini Review

Published on 07 Nov 2025

Loneliness in adolescence: prevalence, developmental contexts, and interventions

in Adolescent and Young Adult Psychiatry

Lily Verity
Lauren Burke
Pamela Qualter

Frontiers in Psychiatry

doi 10.3389/fpsyt.2025.1696981

1,578 views

Policy Brief

Published on 07 Nov 2025

Implementing Indigenous rights through climate–health governance: advancing the Indigenous Determinants of Health framework within the UNFCCC

in Climate, Ecology and People

Geoffrey Scott Roth
Alejandro Bermudez Del Villar
Amina Amharech
Lala Forrest
Matthew Carvalho

Frontiers in Climate

doi 10.3389/fclim.2025.1697881

881 views

Case Report

Published on 07 Nov 2025

Case Report: Testicular teratoma with malignant transformation to melanoma and concurrent metastatic carcinoma of undetermined primary origin in a red deer (Cervus elaphus)

in Veterinary Clinical, Anatomical, and Comparative Pathology

Miguel Criado
Paloma Prieto
Juan José Palomares
Desiderio Lopezosa
David Zapico
Pedro Mendívil
Julio Benavides
M. Carmen Ferreras
José Espinosa

Frontiers in Veterinary Science

doi 10.3389/fvets.2025.1699289

616 views

Original Research

Published on 07 Nov 2025

Feeding fresh food and providing water ad libitum is clinically proven to exceed calculated daily water requirements and impact urine relative supersaturation in dogs

in Animal Nutrition and Metabolism

Rae Sires
Ryan Yamka
Joe Wakshlag

Frontiers in Veterinary Science

doi 10.3389/fvets.2025.1675990

2,255 views

Original Research

Published on 07 Nov 2025

Development and validation of a predictive nomogram for severe adverse drug reactions: a dual-center pharmacovigilance study

in Predictive Toxicology

Wei Bu
Xinjing Wu
Chengyu Wang
Yan Cai

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1669995

694 views

Clinical Trial

Published on 07 Nov 2025

Tissue preserving non-invasive physical plasma treatment for cervical squamous intraepithelial neoplasia grade 3—a prospective randomized, controlled clinical trial

in Obstetrics and Gynecology

Melanie Henes
Sabine Matovina
Robert Rottscholl
You-Shan Feng
Antonia Fleischhacker
Guilin Wang
Markus Enderle
Peter Awakowicz
Sara Y. Brucker
Martin Weiss

Frontiers in Medicine

doi 10.3389/fmed.2025.1669933

657 views

Articles

Ginkgolide C alleviates atherosclerosis by activating LAMP-2A to enhance chaperone-mediated autophagy and promote NLRP3 inflammasome degradation

Pathways and challenges in the clinical translational of radiopharmaceuticals for pediatric investigations

Prognostic value of kappa free light chain index in patients with primary progressive multiple sclerosis

Exophytic colonic carcinoma complicated by gastrocolic fistula mimicking a giant gastric mass: a case report and brief review

Iron oxide nanoparticles empowering melanoma therapy: advances in multifunctional platform research

Relationship between heart rate variability and inflammation induced by physical exercise in a sedentary healthy population

From hormonal immunomodulation to glioblastoma therapy: the emerging role of Ouabain

A retrospective analysis of small molecule targeting inhibitor usage for lung cancer among outpatients in six major regions of China (2016–2022)

L2 growth mindset in AI-mediated language learning: effects of perceived usability and presence of generative AI chatbots

Immune checkpoint inhibitor-induced diabetes can potentially be effectively treated with infliximab: a case report of two patients

Loneliness in adolescence: prevalence, developmental contexts, and interventions

Implementing Indigenous rights through climate–health governance: advancing the Indigenous Determinants of Health framework within the UNFCCC

Case Report: Testicular teratoma with malignant transformation to melanoma and concurrent metastatic carcinoma of undetermined primary origin in a red deer (Cervus elaphus)

Feeding fresh food and providing water ad libitum is clinically proven to exceed calculated daily water requirements and impact urine relative supersaturation in dogs

Development and validation of a predictive nomogram for severe adverse drug reactions: a dual-center pharmacovigilance study

Tissue preserving non-invasive physical plasma treatment for cervical squamous intraepithelial neoplasia grade 3—a prospective randomized, controlled clinical trial