Life Outcomes | List of Frontiers open access articles

Original Research

Published on 10 Nov 2025

Sustained hyperuricemia disrupts enterohepatic circulation through 12α-hydroxy BA and gut microbiota

in Microorganisms in Vertebrate Digestive Systems

Tong Zou
Ruixiao Zhang
Zeqing Chen
Haiping Duan
Zhaoguo Wang
Ruipeng Gao
Xin Chen
Hongqiang Wang
Yue Zhao
Xiaofeng Wang

Frontiers in Microbiology

doi 10.3389/fmicb.2025.1671409

493 views

Original Research

Published on 10 Nov 2025

Modulation of TNFα-driven neuroinflammation by Gardenin A: insights from in vitro, in vivo, and in silico studies

in Inflammation Pharmacology

Prashsti Chadha
Hiral Aghara
Harshrajsinh Solanki
Manali Patel
Dhrubjyoti Sharma
Vijay Thiruvenkatam
Palash Mandal

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1681403

684 views

Original Research

Published on 10 Nov 2025

Loss of FAM134B increased endoplasmic reticulum stress and induced cell autophagy in breast cancer

in Cancer Immunity and Immunotherapy

Zhaoqi Zhang
Yan Fang
Zhibing Qiu
Shuning Ding
Deyue Liu
Wanqiu Huang
Li Zhu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1652888

318 views

Original Research

Published on 10 Nov 2025

Oculomotor indicators of cognitive performance are modulated by neurodegeneration

in Cognitive and Behavioral Neurology

Patrice Voss
Nils A. Koch
Maryse E. Thomas
Paul S. Giacomini
Etienne De Villers-Sidani

Frontiers in Neurology

doi 10.3389/fneur.2025.1649745

232 views

Original Research

Published on 10 Nov 2025

Educational leadership under construction: an experimental study on emotions and task performance using LEGO® bricks

in Leadership in Education

Mercedes Ventura
Noelia Ventura-Campos

Frontiers in Education

doi 10.3389/feduc.2025.1660135

243 views

Original Research

Published on 10 Nov 2025

Comparison of endovascular therapy care and outcome in primary and comprehensive stroke centers for acute ischemic stroke in China a real-world nationwide registry

in Endovascular and Interventional Neurology

Ting-yu Yi
Shujuan Gan
Meihua Wu
Weifeng Huang
Yanmin Wu
Hanming Tu
Changjun Yang
Lihua Xu
Hui Tan
Lin Gao

Frontiers in Neurology

doi 10.3389/fneur.2025.1655954

232 views

Original Research

Published on 10 Nov 2025

Preclinical evaluation of 3D-Printed orthodontic aligners using an electro-typodont model

in Biomechanics

Ammar A. Al Shalabi
Shaima Malik
Hoon Kim
Abdulaziz Alhotan
Ahmed Ghoneima
Tarek M. Elshazly

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1650447

252 views

Original Research

Published on 10 Nov 2025

Consistent microbial responses during the aerobic thaw of Alaskan permafrost soils

in Extreme Microbiology

Joy M. O’Brien
Nathan D. Blais
Hannah Holland-Moritz
Katherine L. Shek
Thomas A. Douglas
Robyn A. Barbato
Jessica Gilman Ernakovich

Frontiers in Microbiology

doi 10.3389/fmicb.2025.1654065

649 views

Original Research

Published on 10 Nov 2025

Does the innovation of digital economy policies improve land allocation efficiency?-a quasi-natural experiment based on the national digital economy innovation and development pilot zone

in Land, Livelihoods and Food Security

Zining Li
Congxin Li

Frontiers in Sustainable Food Systems

doi 10.3389/fsufs.2025.1676352

295 views

Systematic Review

Published on 10 Nov 2025

Human neural correlates of emotional well-being (EWB): a preliminary systematic review and meta-analysis of MRI studies based on a recent consensus definition

in Interacting Minds and Brains

Jie Luo
Celinene M. Lay
Caroline G. Richter
Adam Turnbull
Fabio Richlan
Crystal L. Park
Fumiko Hoeft

Frontiers in Human Neuroscience

doi 10.3389/fnhum.2025.1669164

1,231 views

Original Research

Published on 10 Nov 2025

Abnormal breathing patterns and hyperventilation are common in patients with chronic fatigue syndrome during exercise

in Pulmonary Medicine

Donna M. Mancini
Danielle L. Brunjes
Dane Cook
Tiffany Soto
Michelle Blate
Patrick Quan
Tadahiro Yamazaki
Anna Norweg
Benjamin H. Natelson

Frontiers in Medicine

doi 10.3389/fmed.2025.1669036

1,164 views

Original Research

Published on 10 Nov 2025

A tumor immune microenvironment gene expression signature for predicting prognosis, immunotherapy efficacy, and drug candidates in triple-negative breast cancer

in Cancer Immunity and Immunotherapy

Li Bai
Ziyu Zhou
Qingqing Yu
Zhen Ye
Qingzhou Li
Shengrong Li
Congcong Li
Yu Hu
Yunjie Hu
Xinran Tai

Frontiers in Immunology

doi 10.3389/fimmu.2025.1676768

508 views

Brief Research Report

Published on 10 Nov 2025

Creating multifaceted allied health professionals with skilled hands and the power of words

in Healthcare Professions Education

Urmila Kagal
Sharmila Jalgaonkar
Pankaj Gupta
Nayana Hashilkar

Frontiers in Medicine

doi 10.3389/fmed.2025.1673811

215 views

Original Research

Published on 10 Nov 2025

The immune receptor XA21 causes semi-male sterility and grain loss in rice

in Plant Pathogen Interactions

Beatriz de Toledo Franceschi
Satyam Vergish
Yatendra Singh
Jian-Liang Li
Shamsunnaher
Gao-Lu Ding
Sixue Chen
Wen-Yuan Song

Frontiers in Plant Science

doi 10.3389/fpls.2025.1673821

1,128 views

Original Research

Published on 10 Nov 2025

Tibetan medicine Pa Zhu Wan ameliorates carbon tetrachloride-induced liver fibrosis in rats by regulating the TGF-β-Smad2/3 and IL-6/JAK2/STAT3 signaling pathways

in Ethnopharmacology

Linlin Zhao
Yan Jiang
Jing Ma
Yongjing Yang
Guo Liu
Zhengxing Wang
Tin Wui Wong
Dejun Zhang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1667685

287 views

Original Research

Published on 10 Nov 2025

Effects of auricular acupressure on polysomnography-assessed sleep, blood glucose, and stress in elderly patients with type 2 diabetes and insomnia: a randomized controlled trial

in Sleep Disorders

Jihye Nam
Hyejin Lee
Hyojung Park

Frontiers in Psychiatry

doi 10.3389/fpsyt.2025.1677240

518 views

Articles

Sustained hyperuricemia disrupts enterohepatic circulation through 12α-hydroxy BA and gut microbiota

Modulation of TNFα-driven neuroinflammation by Gardenin A: insights from in vitro, in vivo, and in silico studies

Loss of FAM134B increased endoplasmic reticulum stress and induced cell autophagy in breast cancer

Oculomotor indicators of cognitive performance are modulated by neurodegeneration

Educational leadership under construction: an experimental study on emotions and task performance using LEGO® bricks

Comparison of endovascular therapy care and outcome in primary and comprehensive stroke centers for acute ischemic stroke in China a real-world nationwide registry

Preclinical evaluation of 3D-Printed orthodontic aligners using an electro-typodont model

Consistent microbial responses during the aerobic thaw of Alaskan permafrost soils

Does the innovation of digital economy policies improve land allocation efficiency?-a quasi-natural experiment based on the national digital economy innovation and development pilot zone

Human neural correlates of emotional well-being (EWB): a preliminary systematic review and meta-analysis of MRI studies based on a recent consensus definition

Abnormal breathing patterns and hyperventilation are common in patients with chronic fatigue syndrome during exercise

A tumor immune microenvironment gene expression signature for predicting prognosis, immunotherapy efficacy, and drug candidates in triple-negative breast cancer

Creating multifaceted allied health professionals with skilled hands and the power of words

The immune receptor XA21 causes semi-male sterility and grain loss in rice

Tibetan medicine Pa Zhu Wan ameliorates carbon tetrachloride-induced liver fibrosis in rats by regulating the TGF-β-Smad2/3 and IL-6/JAK2/STAT3 signaling pathways

Effects of auricular acupressure on polysomnography-assessed sleep, blood glucose, and stress in elderly patients with type 2 diabetes and insomnia: a randomized controlled trial