Local Invasion | List of Frontiers open access articles

Original Research

Published on 26 Jun 2025

Molecular mechanisms underlying Fagopyrum dibotrys-derived nanovesicles induced ferroptosis in hepatocellular carcinoma: a dual-pathway analysis of lipid peroxidation and mitochondrial damage

in Ethnopharmacology

Ling Wu
Hongyao Chen
Jingting Zhang
Jincheng Tang
Zhibin Wang
Peisen Xue
Wenhui Gao
Renyi Yang
Puhua Zeng

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1636149

162 views

Original Research

Published on 26 Jun 2025

Zircon Lu-Hf isotopic compositions of the Paleoproterozoic meta-mafic and felsic rock assemblages in the Daqingshan complex: constraints on crustal evolution of the Khondalite Belt, north China Craton

in Geochemistry

Han Wang
Jinfeng Chen
Ningchao Zhou
Xiaoyang Zhang
Weijiang Kong
Ben Ma

Frontiers in Earth Science

doi 10.3389/feart.2025.1632499

342 views

Mini Review

Published on 26 Jun 2025

AI-driven innovation in antibody-drug conjugate design

in In silico Methods and Artificial Intelligence for Drug Discovery

Heather A. Noriega
Xiang Simon Wang

Frontiers in Drug Discovery

doi 10.3389/fddsv.2025.1628789

995 views

Original Research

Published on 26 Jun 2025

Health literacy profiles correlate with participation in primary health care among patients with chronic diseases: a latent profile analysis

in Public Health Education and Promotion

Qi Xu
Baokai Wang
Li Zhang

Frontiers in Public Health

doi 10.3389/fpubh.2025.1628903

171 views

Original Research

Published on 26 Jun 2025

Semi-permeable polymer vesicle-based prooxidative and lactate-depleting nanoreactors with sustained activity against pancreatic cancer

in Biomaterials

Lili Sun
Qian Pan
Yunfei Li
Yanxi Mu
Yusheng Cheng
Yeqian Feng
Masaru Tanaka
Panyue Wen
Xianling Liu

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1626927

202 views

Review

Published on 26 Jun 2025

Inflammatory links between epilepsy and depression: a review of mechanisms and therapeutic strategies

in Neuropharmacology

Yu-Qian Shi
He-Cai Yang
Cong He
Yu-Hao Wang
Jia Zheng
Xing-Yi Wang
Fang-Yi Hao
Chu-Wen Feng
Lin Ma
Yue-Hui Zhang

Frontiers in Neuroscience

doi 10.3389/fnins.2025.1614297

274 views

Review

Published on 26 Jun 2025

Natural bioactive compounds and their mechanisms of action in the management of obesity: a narrative review

in Nutrition and Metabolism

Hassiba Benbaibeche
Ali Zineddine Boumehira
Naim Akhtar Khan

Frontiers in Nutrition

doi 10.3389/fnut.2025.1614947

411 views

Original Research

Published on 26 Jun 2025

Navigating the complexities of teaching rounds: balancing educational and patient-centered objectives

in Healthcare Professions Education

Yang Li
Lu Lu
Yanming Yin
Aijun Wang
Denghui Huang
Wenjiang Yang

Frontiers in Medicine

doi 10.3389/fmed.2025.1615532

179 views

Original Research

Published on 26 Jun 2025

Subcritical fluid and molecular distillation extraction of Nannochloropsis gaditana lipid and its metabolic benefits in hyperlipidemic mice

in Nutrition and Food Science Technology

Ruilong Meng
Yu Zhang
Yishan Jiang
Bin Li
Xi Chen
Zhongliang Sun
Liqin Sun

Frontiers in Nutrition

doi 10.3389/fnut.2025.1615332

268 views

Original Research

Published on 26 Jun 2025

Exploring the association between circadian rhythms and osteoporosis: new diagnostic and therapeutic targets identified via machine learning

in Molecular Diagnostics and Therapeutics

Jian Du
Tian Zhou
Ran Meng
Wei Zhang
Jin Zhou
Wei Peng

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1614221

270 views

Original Research

Published on 26 Jun 2025

Critical care, critical gaps: assessment of burnout and behavioral profiles of ICU healthcare workers in China—a multicenter cross-sectional study

in Public Mental Health

Chao Qing Zhang
Xing Li
Lei He
BinBin Xu
Yan Wu
Junjie He
Wei Wang
Zhong Qian Lu

Frontiers in Public Health

doi 10.3389/fpubh.2025.1617081

245 views

Original Research

Published on 26 Jun 2025

Tissue-engineered tubular substitutions for urinary diversion in a preclinical rabbit model

in Translational Medicine

Qianliang Wang
Qingling Liu

Frontiers in Medicine

doi 10.3389/fmed.2025.1616977

185 views

Original Research

Published on 26 Jun 2025

Reduced synaptic tagging by complement protein C3 is associated with elevated extracellular matrix in the middle-aged cerebellum of mice

in Neurocognitive Aging and Behavior

Henning Peter Düsedau
Carla Cangalaya
Stoyan Stoyanov
Alexander Dityatev
Ildiko Rita Dunay

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1616390

327 views

Original Research

Published on 26 Jun 2025

T cell epitope content comparison using EpiCC correlates with vaccine efficacy against heterologous porcine reproductive and respiratory syndrome virus type 2 strains

in Infectious Agents and Disease

J. Mark Hammer
Andres H. Gutierrez
Lucas Huntimer
Benjamin Gabriel
William D. Martin
Sabine E. Hammer
Tobias Käser
Anne S. De Groot

Frontiers in Microbiology

doi 10.3389/fmicb.2025.1625309

482 views

Systematic Review

Published on 26 Jun 2025

Exercise delays aging: evidence from telomeres and telomerase —a systematic review and meta-analysis of randomized controlled trials

in Exercise Physiology

Liang Sun
Tingran Zhang
Lanfang Luo
Yi Yang
Chuanqiushui Wang
Jiong Luo

Frontiers in Physiology

doi 10.3389/fphys.2025.1627292

302 views

Review

Published on 26 Jun 2025

Unlocking the therapeutic potential of thymus-isolated regulatory T cells

in T Cell Biology

Yueyuan Hu
Hugo Cruz
Samikshya Santosh Nirmala
Anke Fuchs

Frontiers in Immunology

doi 10.3389/fimmu.2025.1612360

142 views

Articles

Molecular mechanisms underlying Fagopyrum dibotrys-derived nanovesicles induced ferroptosis in hepatocellular carcinoma: a dual-pathway analysis of lipid peroxidation and mitochondrial damage

Zircon Lu-Hf isotopic compositions of the Paleoproterozoic meta-mafic and felsic rock assemblages in the Daqingshan complex: constraints on crustal evolution of the Khondalite Belt, north China Craton

AI-driven innovation in antibody-drug conjugate design

Health literacy profiles correlate with participation in primary health care among patients with chronic diseases: a latent profile analysis

Semi-permeable polymer vesicle-based prooxidative and lactate-depleting nanoreactors with sustained activity against pancreatic cancer

Inflammatory links between epilepsy and depression: a review of mechanisms and therapeutic strategies

Natural bioactive compounds and their mechanisms of action in the management of obesity: a narrative review

Navigating the complexities of teaching rounds: balancing educational and patient-centered objectives

Subcritical fluid and molecular distillation extraction of Nannochloropsis gaditana lipid and its metabolic benefits in hyperlipidemic mice

Exploring the association between circadian rhythms and osteoporosis: new diagnostic and therapeutic targets identified via machine learning

Critical care, critical gaps: assessment of burnout and behavioral profiles of ICU healthcare workers in China—a multicenter cross-sectional study

Tissue-engineered tubular substitutions for urinary diversion in a preclinical rabbit model

Reduced synaptic tagging by complement protein C3 is associated with elevated extracellular matrix in the middle-aged cerebellum of mice

T cell epitope content comparison using EpiCC correlates with vaccine efficacy against heterologous porcine reproductive and respiratory syndrome virus type 2 strains

Exercise delays aging: evidence from telomeres and telomerase —a systematic review and meta-analysis of randomized controlled trials

Unlocking the therapeutic potential of thymus-isolated regulatory T cells