Ocean Exploration | List of Frontiers open access articles

Original Research

Published on 01 Oct 2025

Tuina therapy alleviates knee osteoarthritis by modulating PI3K/AKT/mTOR-mediated autophagy: an integrated machine learning and in vivo rat study

in Inflammation

Zhen Wang
Chi Zhao
Mengmeng Li
Lili Zhang
Jieyao Diao
Yiming Wu
Tao Yang
Mingwei Shi
Yang Lei
Yu Wang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1635818

593 views

Original Research

Published on 01 Oct 2025

Integrated proteomics and single-cell transcriptomics reveal potential therapeutic targets in Wilson’s disease patients

in Molecular Innate Immunity

Yue Qi
Minghui Sun
Fang Xu
Hao Zhou
Lihua Yuan
Xinlei Yu
Sirui Cao
Rui Hua

Frontiers in Immunology

doi 10.3389/fimmu.2025.1635137

490 views

Clinical Trial

Published on 01 Oct 2025

Modulation of brain activity and tremor severity by NeuroEpo in Parkinson’s patients with varying tremor amplitudes

in Movement Disorders

Ahmed A. Jiman
Eyad Talal Attar

Frontiers in Neurology

doi 10.3389/fneur.2025.1637184

504 views

Opinion

Published on 01 Oct 2025

Macrophage subtypes and pathways in autoimmune interstitial lung diseases: potential therapeutic targets

in Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

Richa Tyagi
Surya Kant

Frontiers in Immunology

doi 10.3389/fimmu.2025.1638345

393 views

Original Research

Published on 01 Oct 2025

Combined biochar and DMPP reduce N2O emissions in wheat crops via microbial community modulation

in Plant Nutrition

Haizhong Wu
Dengxiao Zhang
Xiaobo Shen
Guozhen Ma
Qingsong Yuan
Hongjing Zhao
Shiliang Liu
Xiaolei Jie
Daichang Wang

Frontiers in Plant Science

doi 10.3389/fpls.2025.1647453

892 views

Original Research

Published on 01 Oct 2025

Elusive and vulnerable: evaluating spatial and temporal variation in the distribution of manta rays around O’ahu using environmental DNA

in Marine Biology

Grace Ann Tuthill-Christensen
Michelle J. Jungbluth
Karen D. Crow

Frontiers in Marine Science

doi 10.3389/fmars.2025.1655518

1,567 views

Review

Published on 01 Oct 2025

Shared immunological pathways in rheumatoid arthritis-related interstitial lung disease

in Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

Jingyi Xu
Changhong Li
Jinxia Zhao
Rong Mu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1630729

339 views

Original Research

Published on 01 Oct 2025

Seaweed and melatonin in the induction of tolerance to recurrent water deficit in papaya

in Plant Abiotic Stress

Thayanne Rangel Ferreira
Giuseppe Tognere Polonini
Letícia Freitas Fonseca
Cristhiane Tatagiba Franco Brandão
Antelmo Ralph Falqueto
Edilson Romais Schmildt
Vinicius de Souza Oliveira
Lúcio de Oliveira Arantes
Enilton Nascimento de Santana
Sara Dousseau-Arantes

Frontiers in Plant Science

doi 10.3389/fpls.2025.1630028

482 views

Original Research

Published on 01 Oct 2025

Hormonal contraceptive use is associated with reduced central serotonergic activity indexed by the loudness dependence of auditory evoked potentials

in Brain Health and Clinical Neuroscience

Henrik Normannseth
Christoffer Hatlestad-Hall
Trine Waage Rygvold
Alena Hadzic
Stein Andersson

Frontiers in Human Neuroscience

doi 10.3389/fnhum.2025.1647425

1,729 views

Methods

Published on 01 Oct 2025

Key considerations for ELISA-based quantification of diverse amyloid beta forms in murine brain homogenates

in Neuroscience Methods and Techniques

Nicole G. Metzendorf
Dag Sehlin
Greta Hultqvist

Frontiers in Neuroscience

doi 10.3389/fnins.2025.1645952

2,194 views

Original Research

Published on 01 Oct 2025

Heart rates, facial expressions and self-reports: a multimodal longitudinal approach of learners' emotions in the foreign language classroom

in AI for Human Learning and Behavior Change

Delphine Guedat-Bittighoffer
Abderrazzaq Moufidi
Jean-Marc Dewaele
David Rousseau
Hugo Voyneau
Pejman Rasti

Frontiers in Artificial Intelligence

doi 10.3389/frai.2025.1604110

1,134 views

Methods

Published on 01 Oct 2025

Evaluating chatbot architectures for public service delivery: balancing functionality, safety, ethics, and adaptability

in Politics of Technology

Theodoros Papadopoulos
Charalampos Alexopoulos
Yannis Charalabidis

Frontiers in Political Science

doi 10.3389/fpos.2025.1601440

499 views

Original Research

Published on 01 Oct 2025

From GWAS signal to function: targeted CRISPR activation enables functional characterization of non-coding SNPs in chickens

in Genome Editing in Animals

Jaewon Kim
Jeon Hoon Han
Minjun Kim
Grace Schmidt
Eunjin Cho
Jun Heon Lee
Tae Hyun Kim

Frontiers in Genome Editing

doi 10.3389/fgeed.2025.1662152

604 views

Systematic Review

Published on 01 Oct 2025

Efficacy and safety of pembrolizumab for the treatment of advanced or recurrent ovarian cancer: a meta-analysis based on single-arm studies

in Cancer Immunity and Immunotherapy

Xiaodong Mi
Liming Tan
Tong Lin
Yimin Yang
Hongmei Liu
Fei Tuo

Frontiers in Immunology

doi 10.3389/fimmu.2025.1662455

554 views

Brief Research Report

Published on 01 Oct 2025

Machine learning–derived genetic risk scores identify IL21 as a predictor of response to omalizumab and dupilumab in asthma

in Genetics and Epidemiology

Ayobami Akenroye
Chengyue Zhang
Tanawin Nopsopon
Sean Kalra
Scott T. Weiss
Matthew R. Moll

Frontiers in Allergy

doi 10.3389/falgy.2025.1670783

417 views

Case Report

Published on 01 Oct 2025

Case Report: Shadows of disappearance: the enigma of completely regressed cutaneous melanoma revealed by lymph node metastasis

in Skin Cancer

Li Wang
Yingxue Li
Xinyan Zhang
Lin Han
Zhangyong Xia

Frontiers in Oncology

doi 10.3389/fonc.2025.1671450

858 views

Articles

Tuina therapy alleviates knee osteoarthritis by modulating PI3K/AKT/mTOR-mediated autophagy: an integrated machine learning and in vivo rat study

Integrated proteomics and single-cell transcriptomics reveal potential therapeutic targets in Wilson’s disease patients

Modulation of brain activity and tremor severity by NeuroEpo in Parkinson’s patients with varying tremor amplitudes

Macrophage subtypes and pathways in autoimmune interstitial lung diseases: potential therapeutic targets

Combined biochar and DMPP reduce N2O emissions in wheat crops via microbial community modulation

Elusive and vulnerable: evaluating spatial and temporal variation in the distribution of manta rays around O’ahu using environmental DNA

Shared immunological pathways in rheumatoid arthritis-related interstitial lung disease

Seaweed and melatonin in the induction of tolerance to recurrent water deficit in papaya

Hormonal contraceptive use is associated with reduced central serotonergic activity indexed by the loudness dependence of auditory evoked potentials

Key considerations for ELISA-based quantification of diverse amyloid beta forms in murine brain homogenates

Heart rates, facial expressions and self-reports: a multimodal longitudinal approach of learners' emotions in the foreign language classroom

Evaluating chatbot architectures for public service delivery: balancing functionality, safety, ethics, and adaptability

From GWAS signal to function: targeted CRISPR activation enables functional characterization of non-coding SNPs in chickens

Efficacy and safety of pembrolizumab for the treatment of advanced or recurrent ovarian cancer: a meta-analysis based on single-arm studies

Machine learning–derived genetic risk scores identify IL21 as a predictor of response to omalizumab and dupilumab in asthma

Case Report: Shadows of disappearance: the enigma of completely regressed cutaneous melanoma revealed by lymph node metastasis