Over Trial Learning | List of Frontiers open access articles

Original Research

Accepted on 13 Oct 2025

Total Alkaloids from Coptis chinensis Franch Ameliorate Hyperlipidemia and Hepatic Steatosis via Dual Pathway Modulation of AMPK/SREBP-1c and PPARα/LXRα in Mice

in Ethnopharmacology

Xiangyang Li
Xiaomin Zhang
Nina Wei
Haibo Peng
Xianli Niu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1662325

Original Research

Accepted on 13 Oct 2025

Bioassay guided isolation of sesamin and fargesin from the hydroalcoholic stem extract of Zanthoxylum armatum DC. inhibited inflammation in CpG-stimulated conventional type 1 dendritic cells

in Experimental Pharmacology and Drug Discovery

Indrajit Singh Ningthoujam
Chayan Mukherjee
Jerina Soibam
Marjit Singh Wangkheimayum
Naresh Chandra Bal
Sunil Kumar Raghav
Brajakishore Singh Chingakham

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1687789

Mini Review

Accepted on 13 Oct 2025

Motor System Modulation by Transcranial Alternating Current Stimulation: Insights from Functional MRI – A Scoping Review

in Neurorehabilitation

Simon Han
Jason Luo
Ivy Tuong Van Vo
Won Kee Chang
Nam-Jong Paik
Ji Soo Choi
Won-Seok Kim

Frontiers in Neurology

doi 10.3389/fneur.2025.1684725

Original Research

Accepted on 13 Oct 2025

Screening and Experimental Validation of Modified Gandou Decoction-Targeted Inhibitors for Alleviating AD Components via Network Pharmacology, Machine Learning, and Molecular Dynamics Simulation

in Experimental Pharmacology and Drug Discovery

Shixin Ye
Shun Zhang
Liangdong Zhang
Guorong Peng
Ming Xie
Xiongfeng Huang
Yousheng Hu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1685866

Original Research

Accepted on 13 Oct 2025

Analysis of the Microstates of Prolonged Disorders of Consciousness

in Neurorehabilitation

Yuzhang Wu
Shangang Feng
Deqiu Cui
Zhongzhen Li
Ruowei Qu
Yifeng Cheng
Yangang Wang
Shaoya Yin
Keke Feng

Frontiers in Neurology

doi 10.3389/fneur.2025.1659809

Original Research

Accepted on 13 Oct 2025

The potential value of the use of berberine in depression: A systematic review and meta-analysis of preclinical studies

in Ethnopharmacology

Bifang Yao
Zhengxiang Long
Xiaojiao Lin
Guangqiang Chen
Xiaoyu Li
Ziqi Ye
Jiahong Liu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1664784

Review

Accepted on 13 Oct 2025

Dual-Regulatory miRNAs: Master Regulators and Therapeutic Targets in Bone-Metastatic Breast Cancer

in Molecular Diagnostics and Therapeutics

Feifei Meng
Mengdi Zhang
Dongqing Pu
Guanxi Shi
Jingwei Li

Frontiers in Molecular Biosciences

doi 10.3389/fmolb.2025.1680908

Editorial

Accepted on 13 Oct 2025

Editorial: Neurocinematics: How the Brain Perceives Audiovisuals

in Perception Science

Celia Andreu-Sánchez
Miguel Ángel Martín-Pascual
José M Delgado-García

Frontiers in Neuroscience

doi 10.3389/fnins.2025.1719407

Original Research

Accepted on 13 Oct 2025

Gender differences in dealing with recurrent implantation failure after fertility treatments: A foundation for adequate support models

in Assisted Reproduction

Pascale Annina Stucki
Michèle Meier
Sarah Charlotte Maria Di Giacopo
Kurt Birchler
Brigitte Leeners

Frontiers in Reproductive Health

doi 10.3389/frph.2025.1698380

Original Research

Accepted on 13 Oct 2025

Rethinking Shared Mobility: Analyzing the Commercial Sustainability of Demand-Responsive Transport in Dubai

in Urban Transportation Systems and Mobility

Utpal Deka
Deepthi Dilip

Frontiers in Sustainable Cities

doi 10.3389/frsc.2025.1688672

Original Research

Accepted on 13 Oct 2025

Trends in Male Infertility Burden in South Asia: A 30-Year Analysis of DALYs, Prevalence, and Future Projections Based on GBD 2021

in Andrology

Kaleem Maqsood
Tahir Mehmood
Humayoun Huma Maqbool
Ali Afzal
Muhammad Faisal Maqbool
Mahnoor Fatima
Tayyba Jan
Samina Ashraf
Muhammad Babar Khawar
Chatchai Muanprasat

Frontiers in Reproductive Health

doi 10.3389/frph.2025.1697925

Review

Accepted on 13 Oct 2025

Prenatal Exposure to Endocrine-Disrupting Chemicals and Childhood Atopic Dermatitis: Epidemiological Evidence

in Microorganisms in Vertebrate Digestive Systems

Yuxin Chen
Le Zhang
Ting Yang
Limei Chen

Frontiers in Microbiology

doi 10.3389/fmicb.2025.1681214

Original Research

Accepted on 13 Oct 2025

Assessment of Groundwater Drought Risk in Arid Regions Using Standardized Indices and Reliability Analysis

in Water and Climate

Soumia Gouahi
Mohammed Hssaisoune
Yassine Ait Brahim
Moussa Ait El Kadi
Mohamed Nehmadou
Lhoussaine Bouchaou

Frontiers in Water

doi 10.3389/frwa.2025.1628691

Original Research

Accepted on 13 Oct 2025

The Impact of Lateral Ankle Ligament Injuries on Ankle Stability and Talar Cartilage Stress: A Finite Element Analysis of Combined Injury Mechanisms

in Biomechanics

Shuai Ji
Liang Sun
Qian Wang
Hongfei Qi
Bo Wu
Bing Du
Chengcheng Zhang
Kun Zhang
Zhong Li
Ming Li

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1697096

Systematic Review

Accepted on 13 Oct 2025

A scoping review of lifestyle adherence among coronary artery disease (CAD) patients and at-risk individuals in South Asian adults

in Public Health and Nutrition

Asim Gamaryani
Vinod Gopaldasani
Shah Khalid Mubarak
Rachel A Jones

Frontiers in Public Health

doi 10.3389/fpubh.2025.1692665

Original Research

Accepted on 13 Oct 2025

Multi-omic analysis of PBMCs in sepsis reveals widespread cytotoxic dysfunction and an increased population of CD69 expressing naïve CD4+ T cells

in Inflammation

Joshua Flynn
Anne-Marie Baird
Eamon Breen
Michael Carty
Ciara S McNevin
Lisa Mcdermott
Elaine Kenny
John Davis Coakley
Thomas Ryan
Derek G Doherty

Frontiers in Immunology

doi 10.3389/fimmu.2025.1667186

Articles

Total Alkaloids from Coptis chinensis Franch Ameliorate Hyperlipidemia and Hepatic Steatosis via Dual Pathway Modulation of AMPK/SREBP-1c and PPARα/LXRα in Mice

Bioassay guided isolation of sesamin and fargesin from the hydroalcoholic stem extract of Zanthoxylum armatum DC. inhibited inflammation in CpG-stimulated conventional type 1 dendritic cells

Motor System Modulation by Transcranial Alternating Current Stimulation: Insights from Functional MRI – A Scoping Review

Screening and Experimental Validation of Modified Gandou Decoction-Targeted Inhibitors for Alleviating AD Components via Network Pharmacology, Machine Learning, and Molecular Dynamics Simulation

Analysis of the Microstates of Prolonged Disorders of Consciousness

The potential value of the use of berberine in depression: A systematic review and meta-analysis of preclinical studies

Dual-Regulatory miRNAs: Master Regulators and Therapeutic Targets in Bone-Metastatic Breast Cancer

Editorial: Neurocinematics: How the Brain Perceives Audiovisuals

Gender differences in dealing with recurrent implantation failure after fertility treatments: A foundation for adequate support models

Rethinking Shared Mobility: Analyzing the Commercial Sustainability of Demand-Responsive Transport in Dubai

Trends in Male Infertility Burden in South Asia: A 30-Year Analysis of DALYs, Prevalence, and Future Projections Based on GBD 2021

Prenatal Exposure to Endocrine-Disrupting Chemicals and Childhood Atopic Dermatitis: Epidemiological Evidence

Assessment of Groundwater Drought Risk in Arid Regions Using Standardized Indices and Reliability Analysis

The Impact of Lateral Ankle Ligament Injuries on Ankle Stability and Talar Cartilage Stress: A Finite Element Analysis of Combined Injury Mechanisms

A scoping review of lifestyle adherence among coronary artery disease (CAD) patients and at-risk individuals in South Asian adults

Multi-omic analysis of PBMCs in sepsis reveals widespread cytotoxic dysfunction and an increased population of CD69 expressing naïve CD4+ T cells