Original Research
Published on 01 Nov 2021
The Phytochemical Rhein Mediates M6A-Independent Suppression of Adipocyte Differentiation
in Nutrigenomics
Frontiers in Nutrition
doi 10.3389/fnut.2021.756803
- 5,225 views
- 21 citations
59 articles related to "Rhein"
Articles
Original Research
Published on 26 Aug 2022
Rhein ameliorates transverse aortic constriction-induced cardiac hypertrophy via regulating STAT3 and p38 MAPK signaling pathways
in Cardiovascular and Smooth Muscle Pharmacology
Frontiers in Pharmacology
doi 10.3389/fphar.2022.940574
- 5,827 views
- 11 citations
Original Research
Published on 26 Sep 2022
Rhein inhibits Chlamydia trachomatis infection by regulating pathogen-host cell
in Infectious Diseases – Surveillance, Prevention and Treatment
Frontiers in Public Health
doi 10.3389/fpubh.2022.1002029
- 11,380 views
- 8 citations
Original Research
Published on 12 Jun 2024
Rhein alleviates MPTP-induced Parkinson’s disease by suppressing neuroinflammation via MAPK/IκB pathway
in Neurodegeneration
Frontiers in Neuroscience
doi 10.3389/fnins.2024.1396345
- 5,238 views
- 13 citations
Original Research
Published on 17 Mar 2022
Rhein Protects Against Severe Acute Pancreatitis In vitro and In vivo by Regulating the JAK2/STAT3 Pathway
in Gastrointestinal and Hepatic Pharmacology
Frontiers in Pharmacology
doi 10.3389/fphar.2022.778221
- 4,833 views
- 19 citations
Original Research
Published on 23 Dec 2020
Pharmacokinetics and Pharmacodynamics of the Combination of Rhein and Curcumin in the Treatment of Chronic Kidney Disease in Rats
in Ethnopharmacology
Frontiers in Pharmacology
doi 10.3389/fphar.2020.573118
- 7,123 views
- 21 citations
Original Research
Published on 28 Jan 2020
Rhein Suppresses Lung Inflammatory Injury Induced by Human Respiratory Syncytial Virus Through Inhibiting NLRP3 Inflammasome Activation via NF-ÎşB Pathway in Mice
in Inflammation Pharmacology
Frontiers in Pharmacology
doi 10.3389/fphar.2019.01600
- 9,838 views
- 80 citations
Original Research
Published on 16 Jun 2025
Rhein restores the sensitivity of mcr-1 carrying multidrug-resistant Escherichia coli to colistin
in Antimicrobials, Resistance and Chemotherapy
Frontiers in Microbiology
doi 10.3389/fmicb.2025.1586553
- 2,757 views
- 4 citations
Original Research
Published on 05 Aug 2024
Molecular dynamic simulation reveals the inhibiting impact of Rhein on wild-type and P29S-mutated Rac1
in Biological Modeling and Simulation
Frontiers in Molecular Biosciences
doi 10.3389/fmolb.2024.1414197
- 2,583 views
Original Research
Published on 10 Sep 2021
Rhein Relieves Oxidative Stress in an Aβ1-42 Oligomer-Burdened Neuron Model by Activating the SIRT1/PGC-1α-Regulated Mitochondrial Biogenesis
in Neuropharmacology
Frontiers in Pharmacology
doi 10.3389/fphar.2021.746711
- 5,959 views
- 35 citations
Original Research
Published on 28 May 2020
Rhein Derivative 4F Inhibits the Malignant Phenotype of Breast Cancer by Downregulating Rac1 Protein
in Pharmacology of Anti-Cancer Drugs
Frontiers in Pharmacology
doi 10.3389/fphar.2020.00754
- 4,477 views
- 26 citations
Original Research
Published on 27 Oct 2022
The effects of rhein on D-GalN/LPS-induced acute liver injury in mice: Results from gut microbiome-metabolomics and host transcriptome analysis
in Nutritional Immunology
Frontiers in Immunology
doi 10.3389/fimmu.2022.971409
- 7,910 views
- 26 citations
Original Research
Published on 06 Feb 2025
Bibliometric analysis of rhein in the treatment of tumors
in Pharmacology of Anti-Cancer Drugs
Frontiers in Oncology
doi 10.3389/fonc.2025.1550016
- 2,559 views
- 2 citations
Original Research
Published on 26 Jan 2026
Rhein protects against renal aging and fibrotic injury by multiple targets through inhibition of TNF-α-mediated autophagy and necroptosis crosstalk
in Renal Pharmacology
Frontiers in Pharmacology
doi 10.3389/fphar.2026.1693000
- 735 views
Systematic Review
Published on 13 Dec 2019
A Significant Association Between Rhein and Diabetic Nephropathy in Animals: A Systematic Review and Meta-Analysis
in Ethnopharmacology
Frontiers in Pharmacology
doi 10.3389/fphar.2019.01473
- 6,891 views
- 36 citations
Review
Published on 17 Aug 2016
A Comprehensive and System Review for the Pharmacological Mechanism of Action of Rhein, an Active Anthraquinone Ingredient
in Ethnopharmacology
Frontiers in Pharmacology
doi 10.3389/fphar.2016.00247
- 13,971 views
- 126 citations