Structure Based Drug Discovery | List of Frontiers open access articles

Original Research

Accepted on 13 Oct 2025

Finite Element Analysis-Based Design and Efficacy Assessment of a Three-Dimensional Anisotropic Heel Cushioning Pad for Diabetic Foot Management

in Biomechanics

Xiong-gang Yang
Xing-xi Hu
Lang-tao Ma
Ming-qi Jiang
Gui-qian Zhang
Sheng Lu

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1694935

Original Research

Accepted on 13 Oct 2025

Construction and Application of the Carbon Peak Model for Chinese Industries --Based on Markal-Macro Model

in Environmental Economics and Management

Qiheng Yuan
Chunlei Zhou
Xiang Chen
Peng Jiang
Junyi Shi
Ji Haoyang

Frontiers in Environmental Science

doi 10.3389/fenvs.2025.1625240

Original Research

Accepted on 13 Oct 2025

Unilateral and Bilateral load-velocity relationships in athletes: evidence from a study in boxers

in Elite Sports and Performance Enhancement

Yemin Han
Yiqing Xie
振牛
Jiawang Jia
Zhen Zhang

Frontiers in Sports and Active Living

doi 10.3389/fspor.2025.1598396

Original Research

Accepted on 13 Oct 2025

Deep Learning-Driven MRI for Accurate Brain Volumetry in Murine Models of Neurodegenerative Diseases

in Brain Imaging Methods

Arno Doelemeyer
Saurabh Vaishampayan
Stefan Zurbruegg
Frédéric Morvan
Giuseppe Locatelli
Derya R. Shimshek
Nicolau Beckmann

Frontiers in Neuroscience

doi 10.3389/fnins.2025.1632169

Original Research

Accepted on 13 Oct 2025

A comparative analysis of Volatile organic compounds in Paeoniae Radix Alba processed using different methods

in Food Chemistry

Yuqing Liu
Yafang Du
Yadan Xiao
Yue Wu
Dan Huang
Xuan Guo

Frontiers in Nutrition

doi 10.3389/fnut.2025.1675150

Original Research

Accepted on 13 Oct 2025

Comparative Risk of Uveitis with Janus Kinase Inhibitors versus Tumor Necrosis Factor Inhibitors in Ankylosing Spondylitis and Psoriatic Diseases: A Target Trial Emulation Study

in Autoimmune and Autoinflammatory Disorders : Autoimmune Disorders

Wei-Hsuan Bai
Pei-Lun Liao
Yi-Chiao Bai
James Cheng-Chung Wei

Frontiers in Immunology

doi 10.3389/fimmu.2025.1673970

Methods

Accepted on 13 Oct 2025

Development of genetic manipulation tools for Pseudomonas oleovorans

in Microbiotechnology

Hongjiao Ke
Zhichao Zhang
Yan Liu
Quan Luo
Xuefeng Lu

Frontiers in Microbiology

doi 10.3389/fmicb.2025.1691967

Original Research

Accepted on 13 Oct 2025

Immobilized Staphylococcus aureus phospholipase C on calcium alginate-chitosan: improved performance and industrial potential in soybean oil refining

in Industrial Biotechnology

Areej Alzahrani
NAJEH KRAYEM
Mona Alonazi
Eman Alshehri
Habib Horchani
Abir Ben Bacha

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1706906

Original Research

Accepted on 13 Oct 2025

Exploring the liver microenvironment following successful therapy for HCV: gene expression profiling and residual T cells infiltration

in Molecular Viral Pathogenesis

Daniel E Millian
Esteban Arroyave
Timothy Wanninger
Santhoshi Krishnan
Daniel Bao
Jared R Zhang
Arvind Rao
Heidi Spratt
Monique R Ferguson
Vincent Chen

Frontiers in Cellular and Infection Microbiology

doi 10.3389/fcimb.2025.1662184

Original Research

Accepted on 13 Oct 2025

Identification of metabolic pathways modulated by GAM and NGAM in the inhibition of Staphylococcus aureus biofilm formation

in Antimicrobials, Resistance and Chemotherapy

Amirmohammed Afsharnia
Arjen Nauta
Andre Groeneveld
Blanca Fernandez-Ciruelos
Mostafa Asadpoor
Gert Folkerts
Saskia Braber
Marc M.s.m. Wosten

Frontiers in Microbiology

doi 10.3389/fmicb.2025.1689343

Correction

Accepted on 13 Oct 2025

Correction: Detection of Ecological Thresholds and Selection of Indicator Taxa for Epibenthic Communities Exposed to Multiple Pressures

in Marine Evolutionary Biology, Biogeography and Species Diversity

Laurie Isabel
David Beauchesne
Christopher W McKindsey
Philippe Archambault

Frontiers in Marine Science

doi 10.3389/fmars.2025.1718286

Original Research

Accepted on 13 Oct 2025

HBHA-ECSIT interaction disrupts macrophage autophagy to promote Mycobacterium tuberculosis persistence

in Microbial Immunology

Yongqiang Li
Xiuping Jia
Xiaoying Wang
Huilian Qiao
Yueyun Ma

Frontiers in Immunology

doi 10.3389/fimmu.2025.1596568

Original Research

Accepted on 13 Oct 2025

High Risk, Low Rest: A New Framework for Monitoring Sleep Vulnerability in Emergency Medicine

in Occupational Health and Safety

Laura Schmidt
Marion Trousselard
Clément Perez
Eve Reynaud
Bérénice Valero
Sophie Schlatter
Karim Tazarourte
Marion Douplat
Stéphanie Mazza

Frontiers in Public Health

doi 10.3389/fpubh.2025.1679296

Original Research

Accepted on 13 Oct 2025

Clinical validation of AWGC-defined cachexia in gastric cancer patients: impact on body composition and quality of life

in Clinical Nutrition

Yan Huang
Xi Wu
Yan Ge
Chen Wang
Xin Ding
Junbo Zuo

Frontiers in Nutrition

doi 10.3389/fnut.2025.1659669

Original Research

Accepted on 13 Oct 2025

Obesity vs. overweight status: Differential predictions to poly-substance use in young adulthood

in Addiction in Adolescents

H. Isabella Lanza
Kailey Waller
Lalaine Sevillano

Frontiers in Adolescent Medicine

doi 10.3389/fradm.2025.1657086

Mini Review

Accepted on 13 Oct 2025

The Clinical Utility of Autoantibodies in Systemic Sclerosis: A Review with a Focus on Cohort Differences and Standardization

in Cytokines and Soluble Mediators in Immunity

Kazuhiro Komura

Frontiers in Immunology

doi 10.3389/fimmu.2025.1691988

Articles

Finite Element Analysis-Based Design and Efficacy Assessment of a Three-Dimensional Anisotropic Heel Cushioning Pad for Diabetic Foot Management

Construction and Application of the Carbon Peak Model for Chinese Industries --Based on Markal-Macro Model

Unilateral and Bilateral load-velocity relationships in athletes: evidence from a study in boxers

Deep Learning-Driven MRI for Accurate Brain Volumetry in Murine Models of Neurodegenerative Diseases

A comparative analysis of Volatile organic compounds in Paeoniae Radix Alba processed using different methods

Comparative Risk of Uveitis with Janus Kinase Inhibitors versus Tumor Necrosis Factor Inhibitors in Ankylosing Spondylitis and Psoriatic Diseases: A Target Trial Emulation Study

Development of genetic manipulation tools for Pseudomonas oleovorans

Immobilized Staphylococcus aureus phospholipase C on calcium alginate-chitosan: improved performance and industrial potential in soybean oil refining

Exploring the liver microenvironment following successful therapy for HCV: gene expression profiling and residual T cells infiltration

Identification of metabolic pathways modulated by GAM and NGAM in the inhibition of Staphylococcus aureus biofilm formation

Correction: Detection of Ecological Thresholds and Selection of Indicator Taxa for Epibenthic Communities Exposed to Multiple Pressures

HBHA-ECSIT interaction disrupts macrophage autophagy to promote Mycobacterium tuberculosis persistence

High Risk, Low Rest: A New Framework for Monitoring Sleep Vulnerability in Emergency Medicine

Clinical validation of AWGC-defined cachexia in gastric cancer patients: impact on body composition and quality of life

Obesity vs. overweight status: Differential predictions to poly-substance use in young adulthood

The Clinical Utility of Autoantibodies in Systemic Sclerosis: A Review with a Focus on Cohort Differences and Standardization