Structure Based Drug Discovery | List of Frontiers open access articles

Original Research

Accepted on 10 Oct 2025

Evaluation of forces on muscles and intervertebral joints during Active Kyphosis-Deepening Exercises in the Dynamic Individual Stimulation and Control for Spine Device (DISC4SPINE, D4S)" a modeling approach - proof of concept study

in Biomechanics and Control of Human Movement

Tomasz Szurmik
Karol Bibrowicz
Katarzyna Nowakowska-Lipiec
Hanna Zadoń
Robert Michnik
Andrzej Waldemar Mitas

Frontiers in Sports and Active Living

doi 10.3389/fspor.2025.1642246

Original Research

Accepted on 10 Oct 2025

Consistent microorganisms respond during aerobic thaw of Alaskan permafrost soils

in Extreme Microbiology

Joy M O'Brien
Nathan D Blais
Hannah Holland-Moritz
Katherine Shek
Tom Douglas
Robyn A Barbato
Jessica Gilman Ernakovich

Frontiers in Microbiology

doi 10.3389/fmicb.2025.1654065

Original Research

Accepted on 10 Oct 2025

Deep Multimodal Biomechanical Analysis for Lower Back Pain Rehabilitation to Improve Patients Stability

in Biosensors and Biomolecular Electronics

Abrar Ashraf
Yanfeng Wu
Shaheryar Najam
Mohammed Alshehri
Yahya Alqahtani
Hanan Aljuaid
Ahmad Jalal
Hui Liu

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1631910

Original Research

Accepted on 10 Oct 2025

Healthcare Needs and Barriers to Care among Female Partners of Male Suspects of Child Sexual Abuse Material Offences in Sweden: A Qualitative Interview Study

in Forensic Psychiatry

Roberth Adebahr
Josephine Savard
Ulrika Åkerstedt
Markus Byström
Charlotte Sparre
Cecilia Hadding
Katarina Görts Öberg
Jussi Jokinen

Frontiers in Psychiatry

doi 10.3389/fpsyt.2025.1618162

Original Research

Accepted on 10 Oct 2025

Relationship between serum mineral levels in the second and third trimester of pregnancy and the risk of gestational diabetes mellitus: a retrospective cohort study

in Nutritional Epidemiology

Yuxin Hao
Na Wang
Sumiao Hong
Yongyi Liu
Guankai Lin
Xiaoyang Xu
You Zhou
Xiaoting Wen
Sun Baochang
Hexing Wang

Frontiers in Nutrition

doi 10.3389/fnut.2025.1634419

Editorial

Accepted on 10 Oct 2025

Editorial: Advances in Synthetic Organic Chemistry at the Biomedical Interface: Honoring Professor Iwao Ojima on the Occasion of his 80th Birthday

in Organic Chemistry

Greta Varchi
Thierry Brigaud

Frontiers in Chemistry

doi 10.3389/fchem.2025.1721249

Original Research

Accepted on 10 Oct 2025

Framework humanization enhances GM3(Neu5Gc)-targeting CAR-T cell function by reducing tonic signaling

in Cancer Immunity and Immunotherapy

Jiaxin Tu
Xinyu Li
Yuge Zhu
Shance Li
Guanyu Zhang
You He
Chaoting Zhang
Zheming Lu

Frontiers in Immunology

doi 10.3389/fimmu.2025.1697732

Original Research

Accepted on 10 Oct 2025

Preputial and scrotal cutaneous mast cell tumors in dogs show no evidence of inherently higher biologic malignancy

in Oncology in Veterinary Medicine

Žiga Žagar
Axel Wehrend
Jarno M Schmidt
Sandra Kuehnel-Lawatsch
Tabea Buehler
Wolf von Bomhard
Martin Kessler

Frontiers in Veterinary Science

doi 10.3389/fvets.2025.1672099

Case Report

Accepted on 10 Oct 2025

Unilateral Pulmonary Edema after Minimally-invasive Redo-double Valve Replacement Procedure - Case report

in Cardiovascular Surgery

Dan Wang
Haibo Ren
Jia Yang

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2025.1662660

Review

Accepted on 10 Oct 2025

Research progress on the diagnostic techniques and vaccine development of bovine herpesvirus types 1

in Veterinary Infectious Diseases

Jianming Zhang
Jian Cao
Liang Cao
Chao Zhang
Liyuan Gong
Xiaohong Kang
Dehong Li
Yang Zhang

Frontiers in Veterinary Science

doi 10.3389/fvets.2025.1703336

Original Research

Accepted on 10 Oct 2025

Association between the atherogenic index of plasma, body mass index, and cardiovascular diseases in Chinese middle and old-aged adults: a mediation analysis

in Cardiovascular Metabolism

Yirui Xu
Mengpin Liu
Wenbo Yang
Wenjiao Zhang
Heze Fan
Yu Xu
Juan Zhou
Zuyi Yuan

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2025.1597749

Original Research

Accepted on 10 Oct 2025

Comparative microbial community analysis of Oreocharis mileensis, a resurrection Plant Species with Extremely Small Populations (PSESP)

in Microbe and Virus Interactions with Plants

Temur Asatulloev
Lei Cai
Ziyoviddin Yusupov
Qiuping Chen
Komiljon Sh. Tojibaev
Weibang SUN

Frontiers in Microbiology

doi 10.3389/fmicb.2025.1692695

Original Research

Accepted on 10 Oct 2025

Loss of Two-pore channel 2 enhances CD8+ T cell cytotoxicity and directly impairs tumour growth via MAPK axis in HCC

in Cancer Immunity and Immunotherapy

Lina Ouologuem
Anna Kübler
Sarah Ouologuem
Amar Hadzic
Jan B. Stöckl
Anna Chiara Siciliano
Stefania Forciniti
Salvatore Nigro
Helena Iuele
Valentina Onesto

Frontiers in Immunology

doi 10.3389/fimmu.2025.1668066

Original Research

Accepted on 10 Oct 2025

The Roles of an Urban Rooftop Garden for the Staff of a Memory Clinic - a Qualitative Post-Occupancy Evaluation

in Environmental Psychology

Nina Oher
Anna Bengtsson
Patrik Grahn

Frontiers in Psychology

doi 10.3389/fpsyg.2025.1646052

Systematic Review

Accepted on 10 Oct 2025

Effectiveness of medical ozone injections into the intervertebral disc on relieving lumbosacral pain--a systematic review and meta-analysis

in Musculoskeletal Pain

Donghui Cao
Xusheng Li
Xiao Zhang
Yanron Tian
Wenbo Gu
Xi Zhu
Haifeng Yuan

Frontiers in Pain Research

doi 10.3389/fpain.2025.1668752

Brief Research Report

Accepted on 10 Oct 2025

Research of Antimicrobial resistance and its Associated Genes distribution in Escherichia coli from Diarrheic Calves in the Ulagai Region of China

in Veterinary Pharmacology and Toxicology

Gao Wei
Zhang xin ying
Miao Sun
Han dong xu
Wang jia ning
Li Yue
Ren San
Yu li dong
Gui Fang
Guo Lei

Frontiers in Veterinary Science

doi 10.3389/fvets.2025.1685829

Articles

Evaluation of forces on muscles and intervertebral joints during Active Kyphosis-Deepening Exercises in the Dynamic Individual Stimulation and Control for Spine Device (DISC4SPINE, D4S)" a modeling approach - proof of concept study

Consistent microorganisms respond during aerobic thaw of Alaskan permafrost soils

Deep Multimodal Biomechanical Analysis for Lower Back Pain Rehabilitation to Improve Patients Stability

Healthcare Needs and Barriers to Care among Female Partners of Male Suspects of Child Sexual Abuse Material Offences in Sweden: A Qualitative Interview Study

Relationship between serum mineral levels in the second and third trimester of pregnancy and the risk of gestational diabetes mellitus: a retrospective cohort study

Editorial: Advances in Synthetic Organic Chemistry at the Biomedical Interface: Honoring Professor Iwao Ojima on the Occasion of his 80th Birthday

Framework humanization enhances GM3(Neu5Gc)-targeting CAR-T cell function by reducing tonic signaling

Preputial and scrotal cutaneous mast cell tumors in dogs show no evidence of inherently higher biologic malignancy

Unilateral Pulmonary Edema after Minimally-invasive Redo-double Valve Replacement Procedure - Case report

Research progress on the diagnostic techniques and vaccine development of bovine herpesvirus types 1

Association between the atherogenic index of plasma, body mass index, and cardiovascular diseases in Chinese middle and old-aged adults: a mediation analysis

Comparative microbial community analysis of Oreocharis mileensis, a resurrection Plant Species with Extremely Small Populations (PSESP)

Loss of Two-pore channel 2 enhances CD8+ T cell cytotoxicity and directly impairs tumour growth via MAPK axis in HCC

The Roles of an Urban Rooftop Garden for the Staff of a Memory Clinic - a Qualitative Post-Occupancy Evaluation

Effectiveness of medical ozone injections into the intervertebral disc on relieving lumbosacral pain--a systematic review and meta-analysis

Research of Antimicrobial resistance and its Associated Genes distribution in Escherichia coli from Diarrheic Calves in the Ulagai Region of China