Synthetic Proteins | List of Frontiers open access articles

Original Research

Published on 03 Oct 2025

Characterization of a sesquiterpene synthase and a short-chain dehydrogenase in zerumbone biosynthesis and the applications in engineered Saccharomyces cerevisiae

in Plant Metabolism and Chemodiversity

Mengdie Xu
Yimeng Xia
Gaowei Fang
Tangli Li
Jing Ma
Dengyu Li
Qiuhui Wei
Lichan Tu
Xiaopu Yin
Tianyuan Hu

Frontiers in Plant Science

doi 10.3389/fpls.2025.1635141

697 views

Systematic Review

Published on 03 Oct 2025

Prevalence of tuberculosis among People Who Use Drugs 2000–2024: a systematic review and meta-analysis

in Infectious Diseases: Epidemiology and Prevention

W. S. Ngowi
O. O. Mandizadza
Minyan Wang
W. T. Shao
Conghua Ji

Frontiers in Public Health

doi 10.3389/fpubh.2025.1635053

517 views

Original Research

Published on 03 Oct 2025

Evaluating the effectiveness of intravenous alteplase in patients with minor non-disabling stroke and severe large vessel stenosis: a retrospective study

in Stroke

Qiong Du
Xiaoxuan Li
Yangli Tang
Xuemei Li
Xijun Li
Haichun Hou
Yang Yan
Xichang Liu
Zhengbiao Huang
Zhenxing Liu

Frontiers in Neurology

doi 10.3389/fneur.2025.1661549

1,062 views

Methods

Published on 03 Oct 2025

On-tissue derivatization for mass spectrometry imaging reveals the distribution of short chain fatty acids in murine digestive tract

in Bacteria and Host

Kaoru Nakagawa
Mami Okamoto
Masako Nishida
Kenta Terashima
Manami Kobayashi
Kanae Teramoto
Akiko Kubo

Frontiers in Cellular and Infection Microbiology

doi 10.3389/fcimb.2025.1584487

593 views

Original Research

Published on 03 Oct 2025

Clinical characteristics and influencing factors of cardiovascular comorbidities in psoriasis

in Cardiovascular Epidemiology and Prevention

Xinrui Dai
Xiaoyue Qin
Zongyang Li

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2025.1586731

553 views

Original Research

Published on 03 Oct 2025

Impact of irrigation and micronutrient treatments on insect herbivore population dynamics in soybean

in Pest Management

Rahul Debnath
Justin George
Ammar B. Bhandari
Rupesh Kariyat
Gadi V. P. Reddy
James P. Glover
Tulsi P. Kharel
Krishna N. Reddy

Frontiers in Agronomy

doi 10.3389/fagro.2025.1571675

1,491 views

Original Research

Published on 03 Oct 2025

Development and validation of a lactate and procalcitonin-based nomogram model for predicting prognosis in ICU sepsis patients

in Emergency Health Services

Kai-Xi Tian
Jie-Xuan Dong
Juan Du
Xu-Bing Huang
Yi Liu

Frontiers in Disaster and Emergency Medicine

doi 10.3389/femer.2025.1612093

236 views

Original Research

Published on 03 Oct 2025

Associations between COVID-19 incidence and environmental stressors in Brazil: a nationwide study from 2020 to 2022

in Air Quality and Health

Leona Hoffmann
Ludmilla Viana Jacobson
Thilo Erbertseder
Moritz Berger
Jörn Rittweger
Rochelle Schneider

Frontiers in Environmental Health

doi 10.3389/fenvh.2025.1635503

378 views

Original Research

Published on 03 Oct 2025

Decoding monocyte heterogeneity in sepsis: a single-cell apoptotic signature for immune stratification and guiding precision therapy

in Inflammation Pharmacology

Wenjuan Duan
Qi Chen
Wei Li
Haiying Zhou
Xiaorong Deng
Yan Zhang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1675887

1,962 views

Mini Review

Published on 03 Oct 2025

Neurochemical crossroads: exploring the neurotransmitter network in chronic pain and depression comorbidity

in Pain Mechanisms and Modulators

Min Ma
Yue Zhang
Kunming Tao
Zhijie Lu

Frontiers in Molecular Neuroscience

doi 10.3389/fnmol.2025.1675814

816 views

Opinion

Published on 03 Oct 2025

Stromal cells unifying the pathology of acute and chronic skeletal muscle injury – clue for novel biomaterials

in Biomaterials

Xianglong Liu

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2025.1684310

571 views

Editorial

Published on 03 Oct 2025

Editorial: Exploring the oral-gut microbiome interactions: pathways to therapeutic strategies and implications for systemic health

in Microbial Symbioses

Romain Lan
Lucas De Paula Ramos
Zhangran Chen
Florence Carrouel

Frontiers in Microbiology

doi 10.3389/fmicb.2025.1691238

1,052 views

Review

Published on 03 Oct 2025

Overcoming resistance to PD-1 and CTLA-4 blockade mechanisms and therapeutic strategies

in Cancer Immunity and Immunotherapy

Xiaodong Wang
Jing He
Gouping Ding
Yixuan Tang
Qianqian Wang

Frontiers in Immunology

doi 10.3389/fimmu.2025.1688699

611 views

Original Research

Published on 03 Oct 2025

Outcome of limb lengthening as a treatment for shortening following successful replantation of traumatic leg amputation: experience with 21 patients

in Orthopedic Surgery

Caifeng Wu
Kai Liu
Shengquan Ren
Mingming Liu
Xiaoheng Ding
Aihemaitijiang Yusufu

Frontiers in Surgery

doi 10.3389/fsurg.2025.1686865

424 views

Original Research

Published on 03 Oct 2025

Association of preoperative systemic inflammation with postoperative conduction block in TAVI patients

in Intensive Care Cardiovascular Medicine

Ying-Lu Shi
Dong-Sheng Di
Cheng-Xin Zhang
Wen-Hui Gong
Sheng-Lin Ge

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2025.1671841

348 views

Review

Published on 03 Oct 2025

Therapeutic potential of traditional Chinese medicine in pancreatic fibrosis: mechanisms of TCM formulas and active ingredients

in Ethnopharmacology

Kexin Gan
Yonghong Hu
Wei Liu
Jiewen Shi
Sen Yang
Jinxin Huang
Xuan Wang
Fu Li

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1609569

630 views

Articles

Characterization of a sesquiterpene synthase and a short-chain dehydrogenase in zerumbone biosynthesis and the applications in engineered Saccharomyces cerevisiae

Prevalence of tuberculosis among People Who Use Drugs 2000–2024: a systematic review and meta-analysis

Evaluating the effectiveness of intravenous alteplase in patients with minor non-disabling stroke and severe large vessel stenosis: a retrospective study

On-tissue derivatization for mass spectrometry imaging reveals the distribution of short chain fatty acids in murine digestive tract

Clinical characteristics and influencing factors of cardiovascular comorbidities in psoriasis

Impact of irrigation and micronutrient treatments on insect herbivore population dynamics in soybean

Development and validation of a lactate and procalcitonin-based nomogram model for predicting prognosis in ICU sepsis patients

Associations between COVID-19 incidence and environmental stressors in Brazil: a nationwide study from 2020 to 2022

Decoding monocyte heterogeneity in sepsis: a single-cell apoptotic signature for immune stratification and guiding precision therapy

Neurochemical crossroads: exploring the neurotransmitter network in chronic pain and depression comorbidity

Stromal cells unifying the pathology of acute and chronic skeletal muscle injury – clue for novel biomaterials

Editorial: Exploring the oral-gut microbiome interactions: pathways to therapeutic strategies and implications for systemic health

Overcoming resistance to PD-1 and CTLA-4 blockade mechanisms and therapeutic strategies

Outcome of limb lengthening as a treatment for shortening following successful replantation of traumatic leg amputation: experience with 21 patients

Association of preoperative systemic inflammation with postoperative conduction block in TAVI patients

Therapeutic potential of traditional Chinese medicine in pancreatic fibrosis: mechanisms of TCM formulas and active ingredients