Thaw | List of Frontiers open access articles

Review

Published on 06 Aug 2025

PKM2-driven metabolic reprogramming in digestive system tumors: mechanisms, therapeutic advances, and clinical challenges

in Cancer Immunity and Immunotherapy

Xinyao Huang
Jianjun He
Haonan Sun
Yi Wu
Renjun Gu
Ziyun Li

Frontiers in Immunology

doi 10.3389/fimmu.2025.1634786

138 views

Original Research

Published on 06 Aug 2025

Time tO last ChemotherApy and death in ovaRian cancEr patients: TO CARE/MITO 42 study, a retrospective analysis of italian MITO centers

in Gynecological Oncology

Giulia Scotto
Anna Galatà
Robert Fruscio
Giulia Besana
Fabio Landoni
Luca Sgro
Alessandra Testi
Fulvio Borella
Gennaro Cormio
Mariangela Gianciotta

Frontiers in Oncology

doi 10.3389/fonc.2025.1641758

135 views

Systematic Review

Published on 06 Aug 2025

Effect of CFTR modulators on glucose homeostasis in children and young adults with cystic fibrosis-related diabetes: a systematic review

in Pediatric Endocrinology

Paola Giordano
Giuseppina Leonetti
Vanja Granberg
Rosa Maria Pia Casolino
Giuseppe Lassandro
Maurizio Delvecchio
Giovanna Linguiti

Frontiers in Endocrinology

doi 10.3389/fendo.2025.1623654

211 views

Core Concept

Published on 06 Aug 2025

Towards SDG 3: How Studying Proteins Helps Treat Muscle Diseases and Keep People Healthy

in Human Health

Mohammed K. Drad
Malissa Underwood
Imed-Eddine Gallouzi

Frontiers for Young Minds

doi 10.3389/frym.2025.1601189

Review

Published on 06 Aug 2025

Mechanisms of the effect of gut microbes on depression through the microbiota-gut-brain axis

in Nutrition, Psychology and Brain Health

Xiangyan Zhou
Sixing Wang
Xiaohui Wang
Xinran Chen
Pei Zhou
Kai Ma
Peng Zhang

Frontiers in Nutrition

doi 10.3389/fnut.2025.1634548

233 views

Original Research

Published on 06 Aug 2025

Automated interpretation of PD-L1 CPS based on multi-AI models integration strategy in gastric cancer

in Cancer Immunity and Immunotherapy

Ting Han
Meng Zhuo
Ziyu Song
Peilin Chen
Shiting Chen
Wei Zhang
Yuanyuan Zhou
Hong Li
Dadong Zhang
Xiaolin Lin

Frontiers in Immunology

doi 10.3389/fimmu.2025.1614099

376 views

Original Research

Published on 06 Aug 2025

Living with a transplanted liver is associated with cytopenias: a nationwide cohort study

in Hepatology

Kajinth Manogarathaas
Nicoline S. Arentoft
Jens G. Hillingsø
Anne Marie R. Jensen
Annette D. Fialla
Gerda E. Villadsen
Peter Holland-Fischer
Shoaib Afzal
Børge G. Nordestgaard
Peter Brown

Frontiers in Gastroenterology

doi 10.3389/fgstr.2025.1543618

228 views

Original Research

Published on 06 Aug 2025

Grape seed extract and L-ascorbic acid exert antineoplastic effects against solid Ehrlich carcinoma in vivo by modulating the tumor microenvironment and Th1/Th2 balance

in Cancer Immunity and Immunotherapy

Dalia S. Morsi
Heba M. R. Hathout
Hind S. AboShabaan
Mahmoud Emam
Manal El-khadragy
Ahmed E. Abdel Moneim
Islam M. El-Garawani
Hagar A. Abu Quora

Frontiers in Immunology

doi 10.3389/fimmu.2025.1635071

161 views

Original Research

Published on 06 Aug 2025

Pathological regression patterns following neoadjuvant chemo-immunotherapy in head and neck squamous cell carcinoma: a pilot study

in Cancer Immunity and Immunotherapy

Dikan Wang
Fanning Zeng
Sien Zhang
Wanming Hu
Yahui Wang
Daiqiao Ouyang
Bin Zeng
Guozhong Zeng
Jingyuan Li
Guiqing Liao

Frontiers in Immunology

doi 10.3389/fimmu.2025.1627442

151 views

Case Report

Published on 06 Aug 2025

Case Report: Reactive T-cell large granular lymphocytes in the bone marrow of a patient with relapsed/refractory multiple myeloma receiving teclistamab

in Hematologic Malignancies

Erin A. Dean
Li-Jun Yang
Robert P. Seifert
John R. Wingard

Frontiers in Oncology

doi 10.3389/fonc.2025.1630929

191 views

Review

Published on 06 Aug 2025

Clinical use and toxicities of bortezomib in pediatric patients: a systematic review

in Obstetric and Pediatric Pharmacology

Zachary C. LeBlanc
Averill Clapp
Samantha Kaplan
Carrie J. Shawber
June K. Wu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1661493

Original Research

Published on 06 Aug 2025

Port green investment strategy under government subsidization and regulation policy

in Marine Affairs and Policy

Fengjue Xie
Zhongyin Zhou

Frontiers in Marine Science

doi 10.3389/fmars.2025.1661382

129 views

Original Research

Published on 06 Aug 2025

Economywide impact of climate shock on agricultural sector, women employment and poverty: a Burkina Faso case study

in Agricultural and Food Economics

Boureima Sawadogo
Ramos E. Mabugu

Frontiers in Sustainable Food Systems

doi 10.3389/fsufs.2025.1604950

334 views

Original Research

Published on 06 Aug 2025

Multimodal approach to the diagnosis of pure neural neuropathy in leprosy

in Infectious Diseases: Pathogenesis and Therapy

Clarissa Neves Spitz
Izabela Jardim Rodrigues Pitta
Isadora Versiani
Anna Maria Sales
Ana Caroline Siquara de Sousa
Mariana Andrea Hacker
Euzenir Nunes Sarno
Roberta Olmo Pinheiro
Marcia Rodrigues Jardim

Frontiers in Medicine

doi 10.3389/fmed.2025.1645960

122 views

Mini Review

Published on 06 Aug 2025

Management of intracardiac thrombosis in newborns: a case series and a narrative review of the literature

in Thrombosis and Haemostasis

Domenico Umberto De Rose
Federico Mecarini
Cosimo Marco Campanale
Flaminia Pugnaloni
Chiara Passarella
Aurelio Secinaro
Giorgio Bracaglia
Matteo Luciani
Alessandra Toscano
Irma Capolupo

Frontiers in Cardiovascular Medicine

doi 10.3389/fcvm.2025.1659312

151 views

Systematic Review

Published on 06 Aug 2025

Effects of resistance exercise on patients with post-stroke dysphagia based on ACSM recommendations: a systematic review of randomized controlled trials

in Exercise Physiology

Yu Ye
Kairui Wu
Yingquan Liu
Hongjie Ji
Hongtao Li
Bo Jiang
Fangyuan Xu
Xuejun Li
Peijia Hu
Hongliang Cheng

Frontiers in Physiology

doi 10.3389/fphys.2025.1623298

234 views

Articles

PKM2-driven metabolic reprogramming in digestive system tumors: mechanisms, therapeutic advances, and clinical challenges

Time tO last ChemotherApy and death in ovaRian cancEr patients: TO CARE/MITO 42 study, a retrospective analysis of italian MITO centers

Effect of CFTR modulators on glucose homeostasis in children and young adults with cystic fibrosis-related diabetes: a systematic review

Towards SDG 3: How Studying Proteins Helps Treat Muscle Diseases and Keep People Healthy

Mechanisms of the effect of gut microbes on depression through the microbiota-gut-brain axis

Automated interpretation of PD-L1 CPS based on multi-AI models integration strategy in gastric cancer

Living with a transplanted liver is associated with cytopenias: a nationwide cohort study

Grape seed extract and L-ascorbic acid exert antineoplastic effects against solid Ehrlich carcinoma in vivo by modulating the tumor microenvironment and Th1/Th2 balance

Pathological regression patterns following neoadjuvant chemo-immunotherapy in head and neck squamous cell carcinoma: a pilot study

Case Report: Reactive T-cell large granular lymphocytes in the bone marrow of a patient with relapsed/refractory multiple myeloma receiving teclistamab

Clinical use and toxicities of bortezomib in pediatric patients: a systematic review

Port green investment strategy under government subsidization and regulation policy

Economywide impact of climate shock on agricultural sector, women employment and poverty: a Burkina Faso case study

Multimodal approach to the diagnosis of pure neural neuropathy in leprosy

Management of intracardiac thrombosis in newborns: a case series and a narrative review of the literature

Effects of resistance exercise on patients with post-stroke dysphagia based on ACSM recommendations: a systematic review of randomized controlled trials