Impact Factor 3.508
2017 JCR, Clarivate Analytics 2018

Frontiers journals are at the top of citation and impact metrics

Original Research ARTICLE Provisionally accepted The full-text will be published soon. Notify me

Front. Neurol. | doi: 10.3389/fneur.2019.00149

Motor nerve conduction tests in carpal tunnel syndrome

  • 1Onze Lieve Vrouwe Gasthuis (OLVG), Netherlands
  • 2Canisius Wilhelmina Hospital, Netherlands
  • 3Franciscus Gasthuis & Vlietland, Netherlands

Background – For the preoperatively often required confirmation of clinically defined carpal tunnel syndrome (CTS), sensory as well as motor nerve conduction studies can be applied. The aim of this study was to test the sensitivity of specific motor nerve conduction tests in comparison with, as well as in addition to, sensory nerve conduction tests.
Methods – In 162 patients with clinically defined CTS, sensory and motor nerve conduction tests were performed prospectively. Sensitivity and specificity of all tests were computed. Also, Receiver Operating Characteristic (ROC) analyses were conducted.
Results – Sensitivity for all sensory tests was at least 79.4% (DIG1). All tests had a specificity of at least 95.7%. The motor conduction test with the highest sensitivity was the TLI-APB (81.3%); its specificity was 97.9%.
Conclusion – In the electrophysiological confirmation of CTS, sensory nerve conduction tests and terminal latency index have a high sensitivity. If, however, sensory nerve action potentials cannot be recorded, all motor nerve conduction tests have a high sensitivity.

Keywords: Carpal Tunnel Syndrome, Nerve conduction studies (NCS), diagnostics, Sensory nerve action potential (SNAP), motor nerve conduction studies

Received: 20 Jun 2018; Accepted: 05 Feb 2019.

Edited by:

Ghazala Hayat, Saint Louis University, United States

Reviewed by:

Raghav Govindarajan, University of Missouri, United States
Giuseppe Piscosquito, Fondazione Salvatore Maugeri, Telese (IRCCS), Italy  

Copyright: © 2019 Kasius, Claes, Verhagen and Meulstee. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

* Correspondence: MD, PhD. Kristel Kasius, Onze Lieve Vrouwe Gasthuis (OLVG), Amsterdam, Netherlands, k.kasius@olvg.nl