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Review ARTICLE Provisionally accepted The full-text will be published soon. Notify me

Front. Neurol. | doi: 10.3389/fneur.2019.00933

Evidence for the role of Magnetic Source Imaging in the presurgical evaluation of refractory epilepsy patients.

 Evelien Carrette1* and Hermann Stefan2
  • 14BRAIN, Ghent University, Belgium
  • 2Department of Neurology-Biomagnetism, University Hospital Erlangen, Germany

The advantages of Magnetoencephalography (MEG) in the field of epilepsy are multiple; just like electroencephalography (EEG), MEG is able to non-invasively measure the epilepsy specific information (i.e. the brain activity reflecting seizures and/or interictal epileptiform discharges) directly and independent of blood flow with a very high temporal resolution in the order of milliseconds. Thanks to its unique sensitivity to tangential sources it gives the full picture when combined with EEG. It allows accurate source imaging of focal epileptic activity and functional cortex and shows a high sensitivity for neocortical sources. In this paper the current evidence and practice for using magnetic source imaging of focal interictal and ictal epileptic activity during the presurgical evaluation of drug resistant patients is being reviewed.

Keywords: Magnetic Source Imaging, refractory epilepsy, presurgical evaluation, equivalent current dipole modeling , magnetoencephalagraphy (MEG)

Received: 12 Feb 2019; Accepted: 12 Aug 2019.

Edited by:

Sandor Beniczky, Aarhus University Hospital, Denmark

Reviewed by:

Gabriel Gonzalez-Escamilla, University Medical Centre, Johannes Gutenberg University Mainz, Germany
Lene Duez, Aarhus University Hospital, Denmark  

Copyright: © 2019 Carrette and Stefan. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

* Correspondence: Dr. Evelien Carrette, Ghent University, 4BRAIN, Ghent, Belgium, Evelien.Carrette@ugent.be