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Original Research ARTICLE Provisionally accepted The full-text will be published soon. Notify me

Front. Neurol. | doi: 10.3389/fneur.2019.01243

Risk factors of external ventricular drainage - related infections: A retrospective study of 147 pediatric post-tumor resection patients in a single center

Pengwei Lu1,  Raynald -2, Wei Liu1, Jian Gong1, Tao Sun1, Chunde Li1, Yanzhu Fan1, Ruifang Zhu1 and  Yongji Tian1*
  • 1Beijing Tiantan Hospital, Capital Medical University, China
  • 2Beijing Neurosurgical Institute, Beijing Tiantan Hospital, Capital Medical University, China

Background: External ventricular drainage (EVD) is common after brain surgery. However, the incidence of EVD related infection (ERI) is still relatively high and can increase morbidity and mortality.
Objective: The objective of this study was to analyze ERI factors in pediatric population post-brain tumor surgery.
Methods: From January 2016 to December 2017, 147 patients less than 18 years old underwent tumor removal at Beijing Tiantan Hospital and had postoperative EVD. We recorded basic demographic data as well as several risk factors. We then analyzed whether these factors were related to ERI.
Results: Patients with a preoperative ventriculo-peritoneal (V-P) shunt, longer operation time, received blood transfusion, more frequent cerebrospinal fluid (CSF) sampling, and longer indwelling time of EVD had higher risks of infection (P<0.05). Logistic regression analysis confirmed that a preoperative V-P shunt, operative duration, intraoperative blood transfusion, frequency of CSF sampling and EVD duration were correlated with postoperative ERI (P<0.05).
Conclusion: EVD should be removed as soon as possible and any unnecessary procedures should be avoided to reduce the infection rate. However, prophylactic treatment should be given in cases of patients do not meet the indication for EVD removal.

Keywords: Evd, Tumor surgery, Risk factors, Infection, Children

Received: 09 Jun 2019; Accepted: 07 Nov 2019.

Copyright: © 2019 Lu, -, Liu, Gong, Sun, Li, Fan, Zhu and Tian. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

* Correspondence: Dr. Yongji Tian, Beijing Tiantan Hospital, Capital Medical University, Beijing, 100050, China, ttyysw1tyj@163.com