Skip to main content

ORIGINAL RESEARCH article

Front. Oncol.
Sec. Cancer Imaging and Image-directed Interventions
Volume 14 - 2024 | doi: 10.3389/fonc.2024.1146972
This article is part of the Research Topic Vascular Malformations: Advancements, Debates, and Consensus View all articles

Microwave Ablation with Hydrodissection used for the treatment of Vascular Malformations: Effectiveness and Safety Study

Provisionally accepted
Lu Wang Lu Wang 1Man Lu Man Lu 1*Min Zhuang Min Zhuang 2Ying Liang Ying Liang 3Shi s. Wang Shi s. Wang 3Jia m. Li Jia m. Li 2
  • 1 Sichuan Cancer Hospital, Chengdu, China
  • 2 Department of Clinical Medicine, North Sichuan Medical College, Nanchong, Anhui Province, China
  • 3 School of Medical and Life Sciences, Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan Province, China

The final, formatted version of the article will be published soon.

    The aim of the study was to investigate the safety, effectiveness, and peripheral nerve protection in ultrasound-guided microwave ablation (US-guided-MWA) for vascular malformations (VMs) closely related to peripheral nerve.From August 2019 to February 2022, 31 patients with 39 VMs received US-guided-MWA. All lesions were confirmed to be closely related to the peripheral nerve by imaging evaluation. Hydrodissection was applied to protect surrounding normal tissue, including peripheral nerves. The patients were followed up at 1day, 2 days, 3 days, 1 week, 1 month, 3 months after operation. Measurements of lesion volume, volume reduction ratio (VRR), sensory and functional abnormalities of adjacent nerves, number of treatments, complication details, personal satisfaction, recurrence, and symptom improvement were recorded. Results: Among the 39 VMs, the maximum volume is 128.58ml, while the minimum volume is 0.99ml. After a mean follow-up of 13.06±4.83 months, the mean numerical rating scale (NRS) score decreased from 5.13±1.65 to 0.53±0.83 (P＜0.0001). The mean mass volume was reduced from 18.34±24.68 ml to 1.35±2.09 ml (P=0.0001). The VRR of all lesions was 92.06%. However, the mean number of treatments was only 1.64±0.87. All patients were satisfied with the technique, with a mean satisfaction score (SC) of 9.23±1.13. There were no motor function abnormalities of the related nerves. 10 patients felt numbness in the ablation area after ablation, and gradually recovered after 1 month. Conclusion: US-guided-MWA serves as a novel alternative approach for patients with VMs. Preoperative evaluation of the relationship between VMs and peripheral nerves combined with intraoperative hydrodissection is an effective and safe method to prevent nerve injury.Vascular malformations (VMs) are complex congenital lesions with various clinical manifestations that may affect patients' lives [1]. VMs include capillary malformations, venous malformations, lymphatic malformations, arteriovenous malformations, congenital arteriovenous malformations, and mixed malformations [2][3]. VMs can involve all parts of the body, including dermis, subcutaneous tissue, muscles, bones, and even internal organs. The ones that affect dermis,

    Keywords: Vascular Malformations closely related to Peripheral Nerve Treated by Microwave Ablation with Hydrodissection 删除了: usually 带格式的: 普通(网站), 缩进: 首行缩进: 0 字符 删除了: drug therapy 设置了格式: 字体: (默认) Times New Roman, (中文) +中文正文 (DengXian), 五号 删除了: more for symptom control [8] 设置了格式: 字体: (默认) Times New Roman, 五号

    Received: 18 Jan 2023; Accepted: 15 May 2024.

    Copyright: © 2024 Wang, Lu, Zhuang, Liang, Wang and Li. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence: Man Lu, Sichuan Cancer Hospital, Chengdu, China

    Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.