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ORIGINAL RESEARCH article

Front. Oncol.
Sec. Breast Cancer
Volume 14 - 2024 | doi: 10.3389/fonc.2024.1325362

Application value of MRI-guided wire localization to the non- palpable breast lesions lesions of the breast only shown in MRI

Provisionally accepted
Jiaqi Ma Jiaqi Ma Leina Hou Leina Hou Xiufen Liang Xiufen Liang Bin Yan Bin Yan Qiang Dai Qiang Dai Hongbian Gao Hongbian Gao Jiang Zhu Jiang Zhu Canxu Song Canxu Song Quan Yuan Quan Yuan Yunmei Wang Yunmei Wang *
  • Shaanxi Provincial Cancer Hospital, Xi'an, China

The final, formatted version of the article will be published soon.

    Magnetic resonance imaging (MRI)-guided wire localization can be applied to assist to remove suspected breast lesions accurately. This study aimed to evaluate the clinical application value of this technique in Chinese women. A total of 126 patients (131 lesions) who had underwent such technique in our hospital from April 2017 to December 2022 were enrolled. 1.5T MRI system and a wire localization device were used. Image characteristics, clinical features and postoperative pathology were collected and analyzed.All of 126 patients (131 lesions) were successfully localized by MRI and excised for biopsy. There were 39 malignant lesions (29.77%) and 92 benign lesions (70.23%). There was no significant correlation between the morphology of DCE-MRI and the ratio of malignant lesions (P=0.763), while there was a statistical correlation between the BPE, TIC curve and the malignancy rate (P<0.05). All the lesions were assessed according to BI-RADS category of MRI (C4A=77, C4B=40, C4C=12, C5=2). The malignancy raterates were as follows: 16.88% for 4A lesions (13/77), 37.50% for 4B lesions (15/40), 66.67% for 4C lesions (8/12) and 100% for 5 lesions (2/2). There was a significant correlation between the BI-RADS category and the incidence of benign-to-malignant lesions (P=0.000). MRI-guided wire localization can assist to remove suspected breast lesions early, safely and accurately. This technique makes up for the deficiency of X-ray and ultrasound, improves the accuracy of diagnosis and resection therapy in intraductal carcinoma and early invasive carcinoma, and helps to improve the prognosis of breast cancer.

    Keywords: MRI, breast cancer, Minimal lesions, MRI-guided, Wire localization

    Received: 21 Oct 2023; Accepted: 30 Apr 2024.

    Copyright: © 2024 Ma, Hou, Liang, Yan, Dai, Gao, Zhu, Song, Yuan and Wang. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence: Yunmei Wang, Shaanxi Provincial Cancer Hospital, Xi'an, China

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