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CASE REPORT article

Front. Oncol.
Sec. Gastrointestinal Cancers: Colorectal Cancer
Volume 14 - 2024 | doi: 10.3389/fonc.2024.1372812
This article is part of the Research Topic Future Frontiers in the Management of Metastatic Colorectal Cancer View all 4 articles

The “appearing” and “disappearing” ascites in the treatment of colorectal cancer - A case report

Provisionally accepted
Hong-Ming Cui Hong-Ming Cui *Dong Peng Dong Peng Zhengqiang Wei Zhengqiang Wei Xing-Ye Wu Xing-Ye Wu *
  • First Affiliated Hospital of Chongqing Medical University, Chongqing, Chongqing Municipality, China

The final, formatted version of the article will be published soon.

    Background Colorectal cancer (CRC) is one of the most common cancers worldwide. In the treatment of CRC patients, oxaliplatin plays a pivotal role with moderate side effect. Neurotoxicity, myelosuppression, ototoxicity, delayed hypersensitivity reactions, and rhabdomyolysis induced by oxaliplatin have been reported individually. However, the occurrence of oxaliplatin-induced ascites has not been reported in the past. Case Description We reported a case of rare ascites in a patient diagnosed with upper rectal cancer and treated with radical surgery plus postoperative chemotherapy using oxaliplatin. Conclusions This case suggested that chemotherapy with oxaliplatin might cause ascites. When CRC patients who underwent chemotherapy with oxaliplatin developed ascites, surgeons should actively determine whether it was caused by chemotherapy side effects or tumor recurrence to avoid unnecessary surgery.

    Keywords: colorectal cancer, chemotherapy, Ascites, oxaliplatin, case report

    Received: 31 Jan 2024; Accepted: 10 May 2024.

    Copyright: © 2024 Cui, Peng, Wei and Wu. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

    * Correspondence:
    Hong-Ming Cui, First Affiliated Hospital of Chongqing Medical University, Chongqing, 400016, Chongqing Municipality, China
    Xing-Ye Wu, First Affiliated Hospital of Chongqing Medical University, Chongqing, 400016, Chongqing Municipality, China

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