CORRECTION article

Front. Physiol., 19 August 2021

Sec. Integrative Physiology

Volume 12 - 2021 | https://doi.org/10.3389/fphys.2021.734320

Corrigendum: Characterising an Alternative Murine Model of Diabetic Cardiomyopathy

  • 1. Heart Failure Pharmacology, Baker Heart and Diabetes Institute, Melbourne, VIC, Australia

  • 2. Department of Diabetes, Central Clinical School, Monash University, Melbourne, VIC, Australia

  • 3. School of Biosciences, The University of Melbourne, Melbourne, VIC, Australia

  • 4. Oxidative Stress Laboratory, Baker Heart and Diabetes Institute, Melbourne, VIC, Australia

  • 5. Preclinical Cardiology, Microsurgery and Imaging Platform, Baker Heart and Diabetes Institute, Melbourne, VIC, Australia

  • 6. Department of Pharmacology and Therapeutics, The University of Melbourne, Melbourne, VIC, Australia

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In the original article, there was a mistake in Figures 1G and H as published. We have noticed that the Y-axis units of both bar graphs are incorrect. The data in these figures is based on the area under the curve (AUC) measurement from glucose tolerance test graphs. We have noticed that the Y-values for glucose have not been multiplied by the time on the X-axis, but rather the row number in the spreadsheet in Prism. The time values had been pasted into the title column and not the x-values column. By correcting the graphs, the actual outcomes for these graphs does not change the results or outcomes of the manuscript. The corrected Figures 1G and H and the entire Figure 1 appears below.

Figure 1

Figure 1

Effect of experimental diabetes (combining low-dose STZ and high fat diet) on metabolic characteristics. (A) Body weight, (B) lean mass, (C) fat mass, (D) blood glucose, (E) percentage glycated haemoglobin (HbA1c) and (F) LV Slc2a4 gene expression (glucose transporter GLUT4). Intraperitoneal glucose tolerance test (IPGTT) at (G) 18 weeks and (H) 26 weeks. Plasma (I) insulin, (J) C-peptide levels and (K) cholesterol at 26 weeks. Data are presented as mean ± SEM. n = 9–33 per group (note individual data points). Data analysed using unpaired t-test. *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001 compared to ND. Blue circles ND; red squares T2DM. ND, non-diabetic; T2DM, type 2 diabetes; HbA1c, glycated haemoglobin; LV, left ventricle; STZ, streptozotocin, AUC, area-under-the-curve.

The authors apologise for this error and state that this does not change the scientific conclusions of the article in any way. The original article has been updated.

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Publisher’s note

All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article, or claim that may be made by its manufacturer, is not guaranteed or endorsed by the publisher.

Summary

Keywords

diabetes, type 2 diabetes, diabetic cardiomyopathy, cardiac, experimental model

Citation

Tate M, Prakoso D, Willis AM, Peng C, Deo M, Qin CX, Walsh JL, Nash DM, Cohen CD, Rofe AK, Sharma A, Kiriazis H, Donner DG, De Haan JB, Watson AMD, De Blasio MJ and Ritchie RH (2021) Corrigendum: Characterising an Alternative Murine Model of Diabetic Cardiomyopathy. Front. Physiol. 12:734320. doi: 10.3389/fphys.2021.734320

Received

30 June 2021

Accepted

27 July 2021

Published

19 August 2021

Volume

12 - 2021

Edited and reviewed by

Paras Kumar Mishra, University of Nebraska Medical Center, United States

Updates

Copyright

*Correspondence: Rebecca H. Ritchie

This article was submitted to Integrative Physiology, a section of the journal Frontiers in Physiology

†These authors share first authorship

‡These authors share senior authorship

Disclaimer

All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.

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