Frontiers in Aging Neuroscience

Original Research

Published on 16 May 2025

Radiological features of gait phenotypes in patients with idiopathic normal pressure hydrocephalus

in Parkinson’s Disease and Aging-related Movement Disorders

Silvia Nicolosi
Massimiliano Todisco
Matteo Paoletti
Eduardo Caverzasi
Francesco Tarantino
Elena Ballante
Francesca Valentino
Roberta Zangaglia
Silvia Figini
Giuseppe Cosentino

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1554642

1,713 views

Original Research

Published on 16 May 2025

Evaluation of functional capacity and risk of depression in older patients with cancer as part of the comprehensive geriatric assessment

in Neurocognitive Aging and Behavior

Wiesław Fidecki
Katarzyna Przylepa
Marek Wytrzyszczewski
Mariusz Wysokiński

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1595336

1,948 views

Original Research

Published on 16 May 2025

Effects of social support on cognitive frailty among the older adults in China: mediation of psychological resilience and moderated mediation of education

in Neurocognitive Aging and Behavior

Wenjuan Li
Yiwen Ma
Jinli Wei
Shanzheng Wu
Liangliang Cui
Chengchao Zhou

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1579485

3,139 views
1 citation

Original Research

Published on 15 May 2025

Mirodenafil improves cognitive function by reducing microglial activation and blood–brain barrier permeability in ApoE4 KI mice

in Alzheimer's Disease and Related Dementias

Yejin Park
Subin Moon
Harry Jung
Songyi Park
Ju Won Kim
Dan-Gyeong Song
Yong-Ho In
Sang Won Han
Jong-Hee Sohn
Chan Hee Lee

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1579411

4,556 views
2 citations

Systematic Review

Published on 15 May 2025

Diagnostic value of olfactory function testing for Alzheimer’s disease and mild cognitive impairment: a systematic review and meta-analysis

in Alzheimer's Disease and Related Dementias

Yuxuan Liu
Yunpeng Cao
Hongquan Wei

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1551939

2,825 views
2 citations

Original Research

Published on 15 May 2025

Predicting brain age for veterans with traumatic brain injuries and healthy controls: an exploratory analysis

in Neurocognitive Aging and Behavior

John P. Coetzee
Xiaojian Kang
Victoria Liou-Johnson
Ines Luttenbacher
Srija Seenivasan
Elika Eshghi
Daya Grewal
Siddhi Shah
Frank Hillary
Emily L. Dennis

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1472207

2,444 views

Review

Published on 14 May 2025

Research status of visuospatial dysfunction and spatial navigation

in Neurocognitive Aging and Behavior

Rui Bao
Shijie Chang
Ruixiang Liu
Yunning Wang
Yifu Guan

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1609620

4,287 views
3 citations

Review

Published on 14 May 2025

Iron responsive elements mRNA regulate Alzheimer’s amyloid precursor protein translation through iron sensing

in Alzheimer's Disease and Related Dementias

Mateen A. Khan

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1483913

3,038 views
2 citations

Correction

Published on 14 May 2025

Corrigendum: Prebiotic effect of fructooligosaccharides from Morinda officinalis on Alzheimer's disease in rodent models by targeting the microbiota-gut-brain axis

in Alzheimer's Disease and Related Dementias

Diling Chen
Xin Yang
Jian Yang
Guoxiao Lai
Tianqiao Yong
Xiaocui Tang
Ou Shuai
Gailian Zhou
Yizhen Xie
Qingping Wu

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1593725

1,553 views

Review

Published on 14 May 2025

Intervention strategies for Parkinson’s disease: the role of exercise and mitochondria

in Parkinson’s Disease and Aging-related Movement Disorders

Ganggang Xu
Chunlian Ma
Yi Yang

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1519672

8,550 views
7 citations

Original Research

Published on 14 May 2025

Plasma neurofilament light chain mediates the effect of subsyndromal symptomatic depression on cognitive decline in older adults

in Alzheimer's Disease and Related Dementias

Chunhua Zhang
Bingyu Li
Kok Pin Ng
Guojuan Huang
Xijin Wang
Min Kong
Maowen Ba

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1547394

2,404 views
1 citation

Original Research

Published on 14 May 2025

Unravelling the interplay: brain regional atrophy and neuropsychological function in early Alzheimer’s disease

in Alzheimer's Disease and Related Dementias

Doyun Heo
Min-Seong Kim
Yun-Jin Lee
Seon-Kyeong Kim
Yong Sung Kim
Wonjae Sung
Hee-Jin Kim

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1508849

3,050 views

Original Research

Published on 14 May 2025

Knowledge map of artificial intelligence in neurodegenerative diseases: a decade-long bibliometric and visualization study

in Parkinson’s Disease and Aging-related Movement Disorders

Junwei Huang
Shuqi Wang
Xuankai Liao
Danting Su
Rubing Lin
Tao Zhang
Long Zhao

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1586282

4,546 views

Original Research

Published on 14 May 2025

Identification and validation of pyroptosis-related genes in Alzheimer’s disease based on multi-transcriptome and machine learning

in Alzheimer's Disease and Related Dementias

Yuntai Wang
Yilin Li
Lu Zhou
Yihuan Yuan
Chuanfei Liu
Zimeng Zeng
Yuanqi Chen
Qi He
Zhuoze Wu

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1568337

4,611 views
2 citations

Original Research

Published on 13 May 2025

Stage-specific functional networks associated with cognitive impairment in Parkinson's disease: a pilot fNIRS study

in Neurocognitive Aging and Behavior

Jiarui Zhao
Yulai Gong
Zhenfang Lin
Jie Yang
Jiahuan Zou
Xia He
Yongsheng He

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1562203

3,444 views
1 citation

Original Research

Published on 13 May 2025

Multimodal neuroimaging investigation of post-stroke fatigue in middle-aged and older adults: combining resting-state fMRI and DTI-ALPS analysis

in Neurocognitive Aging and Behavior

Jingjing Sun
Yanlin Tang
Wenni Wang
Yong Zhang
Hengshan Ji
Peng Wang

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1583655

3,752 views
1 citation

Original Research

Published on 13 May 2025

Assessment of the glymphatic dysfunction in amyotrophic lateral sclerosis using the diffusion tensor imaging along the perivascular spaces index: a pilot study

in Neuroinflammation and Neuropathy

Seol-Hee Baek
Woo-Suk Tae
Jin-Woo Park
Byung-Jo Kim

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1570327

3,689 views
4 citations

Study Protocol

Published on 13 May 2025

Effects and mechanisms of acupuncture for PIGD-subtype Parkinson’s disease via integration of fMRI and gut microbiota-metabolomics analysis: protocol for a prospective randomized controlled trial

in Parkinson’s Disease and Aging-related Movement Disorders

Jili Sheng
Yingqi Xu
Tao Liu
Jianfang Zhu
Caiyun Mu
Lihao Zhai
Shanhu Xu
Hanyi Wang
Xiangzhi Liu
Tao Liu

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1534165

3,297 views

Original Research

Published on 12 May 2025

High serum glial fibrillary acidic protein levels are associated with increased risk of post-stroke cognitive impairment

in Neurocognitive Aging and Behavior

Wanying Shan
Rui Jiang
Jing Wang
Guoli Xu
Jie Zhao
Guojie Zhai
Jiaxin Shao

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1546270

2,168 views

Original Research

Published on 12 May 2025

Implications of heart rate variability measured using wearable electrocardiogram devices in diagnosing Parkinson’s disease and its association with neuroimaging biomarkers: a case-control study

in Parkinson’s Disease and Aging-related Movement Disorders

Mincheol Park
Sung-Woo Kim
Jin Yong Hong
Sung Pil Cho
Junghwan Park
Erdenebayar Urtnasan
Min Seok Baek

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1530240

3,126 views
3 citations

Review

Published on 12 May 2025

Review of FUNDC1-mediated mitochondrial autophagy in Alzheimer’s disease

in Alzheimer's Disease and Related Dementias

Dandan Shi
Xiaochen Guo
Ziqi Ning
Yaoyao Zhang
Fang Liu
Meixia Liu
Yun Wei

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1544241

4,546 views
3 citations

Study Protocol

Published on 12 May 2025

Impact of impaired intrinsic capacity on postoperative frailty in elderly patients undergoing colorectal surgery: study protocol for a single-center, prospective, cohort study

in Neurocognitive Aging and Behavior

Jirun Wang
Shaoqi Tian
Lei Zhang
Jia Liu
Yuefang Liu
Lei Zhu
Peipei Shan
Ping Zhao
Yang Zhao
Youzhuang Zhu

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1523642

3,075 views

Review

Published on 09 May 2025

Early diagnosis of Parkinson’s disease: biomarker study

in Parkinson’s Disease and Aging-related Movement Disorders

Jing Li
Mei Zhang
Chuan-Qing Yu
Min Xue
Pan-Pan Hu

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1495769

6,260 views
5 citations

Original Research

Published on 09 May 2025

Research hotspots and future trends of insomnia in Parkinson’s disease: a bibliometric and visualization analysis from 1973 to 2024

in Parkinson’s Disease and Aging-related Movement Disorders

Xianghong Guo
Tianye Wang
Dan Wang
Jingjing Zhou
Xin Lai

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1535861

2,654 views

7,810 articles

articles

Radiological features of gait phenotypes in patients with idiopathic normal pressure hydrocephalus

Evaluation of functional capacity and risk of depression in older patients with cancer as part of the comprehensive geriatric assessment

Effects of social support on cognitive frailty among the older adults in China: mediation of psychological resilience and moderated mediation of education

Mirodenafil improves cognitive function by reducing microglial activation and blood–brain barrier permeability in ApoE4 KI mice

Diagnostic value of olfactory function testing for Alzheimer’s disease and mild cognitive impairment: a systematic review and meta-analysis

Predicting brain age for veterans with traumatic brain injuries and healthy controls: an exploratory analysis

Research status of visuospatial dysfunction and spatial navigation

Iron responsive elements mRNA regulate Alzheimer’s amyloid precursor protein translation through iron sensing

Corrigendum: Prebiotic effect of fructooligosaccharides from Morinda officinalis on Alzheimer's disease in rodent models by targeting the microbiota-gut-brain axis

Intervention strategies for Parkinson’s disease: the role of exercise and mitochondria

Plasma neurofilament light chain mediates the effect of subsyndromal symptomatic depression on cognitive decline in older adults

Unravelling the interplay: brain regional atrophy and neuropsychological function in early Alzheimer’s disease

Knowledge map of artificial intelligence in neurodegenerative diseases: a decade-long bibliometric and visualization study

Identification and validation of pyroptosis-related genes in Alzheimer’s disease based on multi-transcriptome and machine learning

Stage-specific functional networks associated with cognitive impairment in Parkinson's disease: a pilot fNIRS study

Multimodal neuroimaging investigation of post-stroke fatigue in middle-aged and older adults: combining resting-state fMRI and DTI-ALPS analysis

Assessment of the glymphatic dysfunction in amyotrophic lateral sclerosis using the diffusion tensor imaging along the perivascular spaces index: a pilot study

Effects and mechanisms of acupuncture for PIGD-subtype Parkinson’s disease via integration of fMRI and gut microbiota-metabolomics analysis: protocol for a prospective randomized controlled trial

High serum glial fibrillary acidic protein levels are associated with increased risk of post-stroke cognitive impairment

Implications of heart rate variability measured using wearable electrocardiogram devices in diagnosing Parkinson’s disease and its association with neuroimaging biomarkers: a case-control study

Review of FUNDC1-mediated mitochondrial autophagy in Alzheimer’s disease

Impact of impaired intrinsic capacity on postoperative frailty in elderly patients undergoing colorectal surgery: study protocol for a single-center, prospective, cohort study

Early diagnosis of Parkinson’s disease: biomarker study

Research hotspots and future trends of insomnia in Parkinson’s disease: a bibliometric and visualization analysis from 1973 to 2024