Frontiers in Aging Neuroscience

Review

Published on 12 Feb 2025

Study insights in the role of PGC-1α in neurological diseases: mechanisms and therapeutic potential

in Cellular and Molecular Mechanisms of Brain-aging

Mi-bo Tang
Yi-xuan Liu
Zheng-wei Hu
Hai-yang Luo
Shuo Zhang
Chang-he Shi
Yu-ming Xu

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2024.1454735

6,734 views
12 citations

Original Research

Published on 12 Feb 2025

Bidirectional relationship between depression and activities of daily living and longitudinal mediation of cognitive function in patients with Parkinson’s disease

in Parkinson’s Disease and Aging-related Movement Disorders

Yue Xu
Durong Chen
Meiqi Dong
Yun Zhang
Hongmei Yu
Yanqing Han

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1513373

4,011 views
4 citations

Original Research

Published on 12 Feb 2025

Exploring cognitive and neuroimaging profiles of dementia subtypes of individuals with dementia in the Democratic Republic of Congo

in Alzheimer's Disease and Related Dementias

Jean Ikanga
Saranya Sundaram Patel
Megan Schwinne
Caterina Obenauf
Emmanuel Epenge
Guy Gikelekele
Nathan Tshengele
Immaculee Kavugho
Samuel Mampunza
Lelo Mananga

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1552348

3,177 views
1 citation

Original Research

Published on 12 Feb 2025

Quantification and correlation of amyloid-β plaque load, glial activation, GABAergic interneuron numbers, and cognitive decline in the young TgF344-AD rat model of Alzheimer’s disease

in Neurocognitive Aging and Behavior

Anett Futácsi
Kitti Rusznák
Gergely Szarka
Béla Völgyi
Ove Wiborg
Boldizsár Czéh

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1542229

4,724 views
3 citations

Editorial

Published on 12 Feb 2025

Editorial: To Know or Not to Know: causes and evolution of lack of awareness of cognitive decline in neurodegenerative diseases, volume II

in Neurocognitive Aging and Behavior

Federica Cacciamani
Kristy A. Nielson
Bernard J. Hanseeuw
Geoffroy P. Gagliardi
Patrizia Vannini

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1568173

2,296 views

Original Research

Published on 12 Feb 2025

Multimodal fusion model for diagnosing mild cognitive impairment in unilateral middle cerebral artery steno-occlusive disease

in Neurocognitive Aging and Behavior

Ziyi Yuan
Zhaodi Huang
Chaojun Li
Shengrong Li
Qingguo Ren
Xiaona Xia
Qingjun Jiang
Daoqiang Zhang
Qi Zhu
Xiangshui Meng

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1527323

2,652 views
2 citations

Original Research

Published on 11 Feb 2025

Improved early postoperative cognition in elderly gastrointestinal patients: a randomized controlled trial on the role of ultrasound-guided stellate ganglion block

in Neurocognitive Aging and Behavior

Ruyue Xue
Yuexian Li
Mei Zhan
Lin Yang
Defeng Sun

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1503314

3,378 views
3 citations

Systematic Review

Published on 11 Feb 2025

Effects of exercise training on the nigrostriatal glutamatergic pathway and receptor interactions in Parkinson’s disease: a systematic review

in Parkinson’s Disease and Aging-related Movement Disorders

Shahid Ishaq
Iqbal Ali Shah
Shin-Da Lee
Bor-Tsang Wu

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1512278

5,319 views
1 citation

Original Research

Published on 10 Feb 2025

Multiparameter resting-state functional magnetic resonance imaging as an indicator of neuropsychological changes in Binswanger’s disease with mild cognitive impairment

in Neurocognitive Aging and Behavior

Haiyi Zhang
Lu Zhang
Juan Lu
Jiajun Yue
Zhengzhen Yuan
Jidan Hu
Qi Yao
Yuting Fu
Guiquan Chen
Jiliang Fang

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1522591

2,760 views
1 citation

Brief Research Report

Published on 10 Feb 2025

Microvascular dysfunction in a murine model of Alzheimer’s disease using intravital microscopy

in Alzheimer's Disease and Related Dementias

Danielle Sidsworth
Noah Tregobov
Colin Jamieson
Jennifer Reutens-Hernandez
Joshua Yoon
Geoffrey W. Payne
Stephanie L. Sellers

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1482250

2,255 views

Original Research

Published on 07 Feb 2025

Optineurin overexpression ameliorates neurodegeneration through regulating neuroinflammation and mitochondrial quality in a murine model of amyotrophic lateral sclerosis

in Cellular and Molecular Mechanisms of Brain-aging

Shumin Zhao
Ranran Chen
Yi An
Yali Zhang
Cheng Ma
Ying Gao
Yanchao Lu
Fei Yang
Xue Bai
Jingjing Zhang

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1522073

3,305 views
3 citations

Correction

Published on 07 Feb 2025

Corrigendum: Multidimensional features of sporadic Creutzfeldt-Jakob disease in the elderly: a case report and systematic review

in Alzheimer's Disease and Related Dementias

Jiangfeng Liao
Wenming Hu
Shiheng Chen
Chunyu Huang
Senwei Dong
Wanjin Chen
Xiaochun Chen
Longfei Chen

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1565464

1,894 views

Original Research

Published on 07 Feb 2025

Higher systemic immune-inflammation index is associated with increased risk of Parkinson’s disease in adults: a nationwide population-based study

in Parkinson’s Disease and Aging-related Movement Disorders

Jiayu Zhao
Zhipeng Wu
Fengyin Cai
Xuejv Yu
Zhenyu Song

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1529197

4,940 views
5 citations

Original Research

Published on 07 Feb 2025

Association between carotid artery hemodynamics and neurovascular coupling in cerebral small vessel disease: an exploratory study

in Neurocognitive Aging and Behavior

Peng Zeng
Bang Zeng
Xiaohua Wang
Feiyue Yin
Binglan Li
Lisha Nie
Lin Tian
Dan Luo
Yongmei Li

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1536552

3,338 views
1 citation

Original Research

Published on 07 Feb 2025

Brain compensatory activation during Stroop task in patients with mild cognitive impairment: a functional near-infrared spectroscopy study

in Neurocognitive Aging and Behavior

Chenyu Fan
Hanfei Li
Ke Chen
Guohui Yang
Hongyu Xie
Haozheng Li
Yi Wu
Meng Li

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1470747

4,214 views
10 citations

Original Research

Published on 05 Feb 2025

Role of visual function and performance of activities of daily living in cognitive function in patients with mild cognitive impairment: a cross-sectional study

in Neurocognitive Aging and Behavior

Chunhui Zhou
Ganfeng Yang
Marc Theeboom
Hua Yang
Ruiting Zhu
Zijian Zhou
Dong Zhu

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1505815

3,686 views
6 citations

Original Research

Published on 05 Feb 2025

Sex-specific associations between estimated glucose disposal rate and cognitive decline in middle-aged and older adults in China: a longitudinal cohort study

in Neurocognitive Aging and Behavior

Chun Luo
Shuang Han
Xiaoying Shen
Hao Wu
Jianqing Zhou
Bingyang Liu

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1544352

4,859 views
4 citations

Mini Review

Published on 05 Feb 2025

A synthesized view of the CSF-blood barrier and its surgical implications for aging disorders

in Cellular and Molecular Mechanisms of Brain-aging

Birra Taha
Robert McGovern
Cornelius Lam

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2024.1492449

2,624 views

Systematic Review

Published on 05 Feb 2025

A systematic review of the efficacy of repetitive transcranial magnetic stimulation in treating dysarthria in patients with Parkinson's disease

in Neurocognitive Aging and Behavior

Kerong Chen
Sitong Zhou
Shiyu Lu
Yuliang Qin
Xinyao Li
Yi Li
Tianyun Liu
Mei Zhang
Kun Xu
Hongping Shi

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1501640

3,742 views
1 citation

Original Research

Published on 04 Feb 2025

Auditory steady state response can predict declining EF in healthy elderly individuals

in Neurocognitive Aging and Behavior

Xiaopeng Mao
Nelly Shenton
Sadasivan Puthusserypady
Martin Johannes Lauritzen
Krisztina Benedek

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1516932

2,741 views
1 citation

Original Research

Published on 04 Feb 2025

Association between hemoglobin glycation index and poor outcome after endovascular thrombectomy in acute ischemic stroke

in Neuroinflammation and Neuropathy

Yan Yang
Mei Liu
Shungui Huang
Chen Zhu
Guangzong Li
Bin Wang
Xiaojing Luo
Lingwen Zhang
Weizheng Song

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1533584

2,893 views

Original Research

Published on 04 Feb 2025

Reduction of orexin-expressing neurons and a unique sleep phenotype in the Tg-SwDI mouse model of Alzheimer’s disease

in Alzheimer's Disease and Related Dementias

Yan Wu
Narayan R. Bhat
Meng Liu

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1529769

3,728 views

Original Research

Published on 04 Feb 2025

Investigating dynamic brain functional redundancy as a mechanism of cognitive reserve

in Neurocognitive Aging and Behavior

Julia Schwarz
Franziska Zistler
Adriana Usheva
Anika Fix
Sebastian Zinn
Juliana Zimmermann
Franziska Knolle
Gerhard Schneider
Rachel Nuttall

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1535657

2,897 views
1 citation

Original Research

Published on 04 Feb 2025

Identification of Parkinson’s disease using MRI and genetic data from the PPMI cohort: an improved machine learning fusion approach

in Parkinson’s Disease and Aging-related Movement Disorders

Yifeng Yang
Liangyun Hu
Yang Chen
Weidong Gu
Guangwu Lin
YuanZhong Xie
Shengdong Nie

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1510192

6,097 views
6 citations

7,819 articles

articles

Study insights in the role of PGC-1α in neurological diseases: mechanisms and therapeutic potential

Bidirectional relationship between depression and activities of daily living and longitudinal mediation of cognitive function in patients with Parkinson’s disease

Exploring cognitive and neuroimaging profiles of dementia subtypes of individuals with dementia in the Democratic Republic of Congo

Quantification and correlation of amyloid-β plaque load, glial activation, GABAergic interneuron numbers, and cognitive decline in the young TgF344-AD rat model of Alzheimer’s disease

Editorial: To Know or Not to Know: causes and evolution of lack of awareness of cognitive decline in neurodegenerative diseases, volume II

Multimodal fusion model for diagnosing mild cognitive impairment in unilateral middle cerebral artery steno-occlusive disease

Improved early postoperative cognition in elderly gastrointestinal patients: a randomized controlled trial on the role of ultrasound-guided stellate ganglion block

Effects of exercise training on the nigrostriatal glutamatergic pathway and receptor interactions in Parkinson’s disease: a systematic review

Multiparameter resting-state functional magnetic resonance imaging as an indicator of neuropsychological changes in Binswanger’s disease with mild cognitive impairment

Microvascular dysfunction in a murine model of Alzheimer’s disease using intravital microscopy

Optineurin overexpression ameliorates neurodegeneration through regulating neuroinflammation and mitochondrial quality in a murine model of amyotrophic lateral sclerosis

Corrigendum: Multidimensional features of sporadic Creutzfeldt-Jakob disease in the elderly: a case report and systematic review

Higher systemic immune-inflammation index is associated with increased risk of Parkinson’s disease in adults: a nationwide population-based study

Association between carotid artery hemodynamics and neurovascular coupling in cerebral small vessel disease: an exploratory study

Brain compensatory activation during Stroop task in patients with mild cognitive impairment: a functional near-infrared spectroscopy study

Role of visual function and performance of activities of daily living in cognitive function in patients with mild cognitive impairment: a cross-sectional study

Sex-specific associations between estimated glucose disposal rate and cognitive decline in middle-aged and older adults in China: a longitudinal cohort study

A synthesized view of the CSF-blood barrier and its surgical implications for aging disorders

A systematic review of the efficacy of repetitive transcranial magnetic stimulation in treating dysarthria in patients with Parkinson's disease

Auditory steady state response can predict declining EF in healthy elderly individuals

Association between hemoglobin glycation index and poor outcome after endovascular thrombectomy in acute ischemic stroke

Reduction of orexin-expressing neurons and a unique sleep phenotype in the Tg-SwDI mouse model of Alzheimer’s disease

Investigating dynamic brain functional redundancy as a mechanism of cognitive reserve

Identification of Parkinson’s disease using MRI and genetic data from the PPMI cohort: an improved machine learning fusion approach