Frontiers in Aging Neuroscience

Original Research

Published on 04 Jun 2025

Non-linear relationship between calf circumference and global cognition in Chinese population: a cross-sectional study of 12,102 Chinese older adults

in Neurocognitive Aging and Behavior

Yuting Nie
Cheng Gu
Ruipeng Wu
Fulin Gao
Le Zhang
Yamin Zhang

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1473135

915 views

Original Research

Accepted on 03 Jun 2025

A new pathway for neuroprotection against Tau hyperphosphorylation via δ-Opioid receptor initiated inhibition of CDK5 and AMPK signaling

in Alzheimer's Disease and Related Dementias

Jiahui Li
Yuan Xu
Gianfranco Balboni
Ying Xia

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1587219

143 views

Original Research

Accepted on 03 Jun 2025

Voxel-based and surface-based morphometry in the cortical thickness, and cortical and subcortical grey matter volume in patients with mild to moderate Alzheimer's disease

in Alzheimer's Disease and Related Dementias

Kaidi Li
Dingling Xie
Zhengyong Zhang
Chunyu Fu
Chunyang Li

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1546977

171 views

Original Research

Accepted on 03 Jun 2025

Lower hippocampal volumes at baseline are associated with higher volume loss in healthy elderly

in Neurocognitive Aging and Behavior

Vivian Schultz
Benita Schmitz-Koep
Aurore Menegaux
Melissa Thalhammer
Severin Schramm
Su Hwan Kim
Claus Zimmer
Christian Sorg
Panteleimon Giannakopoulos
Marie-Louise Montandon

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1542857

106 views

Original Research

Accepted on 02 Jun 2025

Altered automatic gaze processing in older adults

in Neurocognitive Aging and Behavior

Roger Koenig-Robert
Boris Barrientos
Phoebe E Bailey
Kiley Seymour

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1592763

165 views

Review

Published on 02 Jun 2025

Neurobiological and therapeutic landmarks of depression associated with Alzheimer’s disease dementia

in Alzheimer's Disease and Related Dementias

Ilinca Untu
Michael Davidson
Gabriela-Dumitrita Stanciu
Jonathan Rabinowitz
Romeo-Petru Dobrin
Diana-Sabina Vieru
Bogdan-Ionel Tamba

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1584607

817 views

Review

Published on 02 Jun 2025

Research progress of deubiquitinating enzymes in cerebral ischemia-reperfusion injury

in Neuroinflammation and Neuropathy

XiaoHong Qin
JiangRui Zhu
HaoRan Lu
MaoRui Yi
ZiLong Zhao
WenFei Zhang
Jing Cheng

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1588920

986 views

Review

Accepted on 30 May 2025

Dysregulated calcium signaling in the aged primate association cortices: Vulnerability to Alzheimer's disease neuropathology

in Alzheimer's Disease and Related Dementias

Amy F T Arnsten
Isabella Perone
Min Wang
Shengtao Yang
Stacy Uchendu
Dinar Bolat
Dibyadeep Datta

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1610350

196 views

Original Research

Accepted on 30 May 2025

Modeling heterogeneity in cognitive trajectories in the Framingham Heart Study

in Neurocognitive Aging and Behavior

Yuan Fang
Jiachen Chen
Jesse Mez
Claudia L Satizabal
Michael L Alosco
Wei Qiao (Wendy) Qiu
Margaret F Doyle
Joanne M Murabito
Kathryn L Lunetta

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1471154

142 views

Original Research

Published on 30 May 2025

Healthy aging in rats is associated with a decline in the ability to inhibit maladaptive responses, but not in measures of self-control by delayed gratification

in Neurocognitive Aging and Behavior

Adam T. Brockett
Xavier Sciarillo
Xuan Li
Matthew R. Roesch

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1579934

550 views

Study Protocol

Published on 30 May 2025

Effect of transcranial magnetic stimulation combined with transcutaneous auricular vagus nerve stimulation on mild cognitive impairment: a study protocol for a randomized controlled trial

in Neurocognitive Aging and Behavior

Jingjing Zhang
Jun Ma
Yao Rao
Jiali Wu
Hui Xu
Jiawei Ni
Zhiwei Zhao
Cong Wang
Chunlei Shan

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1600921

836 views

Original Research

Published on 30 May 2025

Triglyceride-glucose indices predict all-cause mortality after stroke in NHANES 1999–2018

in Neuroinflammation and Neuropathy

Jiaqian Zheng
Weiwen Mao
Mengqian Sang
Xinyu Pan
Yiluo Xie
Yichi Xie

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1617419

840 views

Original Research

Published on 30 May 2025

Potential cerebrospinal fluid metabolomic biomarkers and early prediction model for Parkinson’s disease

in Parkinson’s Disease and Aging-related Movement Disorders

Yifan Zhang
Yuexin Yan
Xiangxu Kong
Haijun Zhang
Shengyuan Su

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1582362

678 views

Systematic Review

Published on 30 May 2025

Bibliometric analysis of global research on PD-L1/PD-1 pathway and neurodegenerative diseases over the last two decades (2004–2023)

in Neurocognitive Aging and Behavior

Jialin Wu
Chaojin Zhang
Qiang Cao
Wei Xuan
Xiaorong Huai
Jie Zhou
Jie Tian

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1570428

803 views

Original Research

Published on 30 May 2025

Risk factors and mediation role of sleep quality for depression in cognitively frail older adults: a cross-sectional study

in Neurocognitive Aging and Behavior

Xiaoxing Lai
Yonghua Cai
Hongwei Zhu
Zhiyuan Zhang
Xinyue Zhang
Yang Li
Jiazhen Liu
Xiaopeng Huo

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1541555

491 views

Original Research

Published on 30 May 2025

Blood essential trace elements and Alzheimer’s disease biomarkers in midlife

in Alzheimer's Disease and Related Dementias

Xin Wang
Kelly M. Bakulski
Carrie A. Karvonen-Gutierrez
Sung Kyun Park
David Morgan
Brian P. Jackson
Roger L. Albin
Henry L. Paulson

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1539749

653 views