Frontiers in Aging Neuroscience

Review

Accepted on 30 May 2025

Dysregulated calcium signaling in the aged primate association cortices: Vulnerability to Alzheimer's disease neuropathology

in Alzheimer's Disease and Related Dementias

Amy F T Arnsten
Isabella Perone
Min Wang
Shengtao Yang
Stacy Uchendu
Dinar Bolat
Dibyadeep Datta

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1610350

169 views

Original Research

Accepted on 30 May 2025

The burden of Parkinson's disease, 1990-2021: a systematic analysis of the global burden of disease study 2021

in Parkinson’s Disease and Aging-related Movement Disorders

Xi-Chen Wu
Yi-Yue Dong
Yu-Chen Ying
Guang-Yan Chen
Qian Fan
Ping Yin
Yue-Lai Chen

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1596392

182 views

Original Research

Accepted on 30 May 2025

Impact of Cognitive Decline on the Physical Functioning of Older Adults in Southern Brazil: A Cross-Sectional Study

in Alzheimer's Disease and Related Dementias

Andréa Kruger Gonçalves
Valeria Feijo Martins
Ana Carolina Kanitz
Flávia Gomes Martinez
Leonardo Alexandre Peyré-Tartaruga
Raphael Machado Castilhos
Aline Nogueira Haas

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1549764

160 views

Original Research

Accepted on 30 May 2025

Modeling heterogeneity in cognitive trajectories in the Framingham Heart Study

in Neurocognitive Aging and Behavior

Yuan Fang
Jiachen Chen
Jesse Mez
Claudia L Satizabal
Michael L Alosco
Wei Qiao (Wendy) Qiu
Margaret F Doyle
Joanne M Murabito
Kathryn L Lunetta

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1471154

115 views

Original Research

Published on 30 May 2025

Triglyceride-glucose indices predict all-cause mortality after stroke in NHANES 1999–2018

in Neuroinflammation and Neuropathy

Jiaqian Zheng
Weiwen Mao
Mengqian Sang
Xinyu Pan
Yiluo Xie
Yichi Xie

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1617419

449 views

Study Protocol

Published on 30 May 2025

Effect of transcranial magnetic stimulation combined with transcutaneous auricular vagus nerve stimulation on mild cognitive impairment: a study protocol for a randomized controlled trial

in Neurocognitive Aging and Behavior

Jingjing Zhang
Jun Ma
Yao Rao
Jiali Wu
Hui Xu
Jiawei Ni
Zhiwei Zhao
Cong Wang
Chunlei Shan

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1600921

551 views

Original Research

Published on 30 May 2025

Healthy aging in rats is associated with a decline in the ability to inhibit maladaptive responses, but not in measures of self-control by delayed gratification

in Neurocognitive Aging and Behavior

Adam T. Brockett
Xavier Sciarillo
Xuan Li
Matthew R. Roesch

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1579934

438 views

Systematic Review

Published on 30 May 2025

Bibliometric analysis of global research on PD-L1/PD-1 pathway and neurodegenerative diseases over the last two decades (2004–2023)

in Neurocognitive Aging and Behavior

Jialin Wu
Chaojin Zhang
Qiang Cao
Wei Xuan
Xiaorong Huai
Jie Zhou
Jie Tian

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1570428

576 views

Original Research

Published on 30 May 2025

Potential cerebrospinal fluid metabolomic biomarkers and early prediction model for Parkinson’s disease

in Parkinson’s Disease and Aging-related Movement Disorders

Yifan Zhang
Yuexin Yan
Xiangxu Kong
Haijun Zhang
Shengyuan Su

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1582362

410 views

Original Research

Published on 30 May 2025

Integrative single-cell and cell-free plasma RNA transcriptomics identifies biomarkers for early non-invasive AD screening

in Alzheimer's Disease and Related Dementias

Li Wu
Renxin Zhang
Yichao Wang
Shaoxing Dai
Naixue Yang

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1571783

536 views

Original Research

Published on 30 May 2025

Global and tract-specific differences between younger and older adults in DTI measures of white matter integrity

in Neurocognitive Aging and Behavior

Stephanie Matijevic
Lee Ryan

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1562660

320 views

Original Research

Published on 30 May 2025

Blood essential trace elements and Alzheimer’s disease biomarkers in midlife

in Alzheimer's Disease and Related Dementias

Xin Wang
Kelly M. Bakulski
Carrie A. Karvonen-Gutierrez
Sung Kyun Park
David Morgan
Brian P. Jackson
Roger L. Albin
Henry L. Paulson

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1539749

426 views

Original Research

Published on 30 May 2025

Risk factors and mediation role of sleep quality for depression in cognitively frail older adults: a cross-sectional study

in Neurocognitive Aging and Behavior

Xiaoxing Lai
Yonghua Cai
Hongwei Zhu
Zhiyuan Zhang
Xinyue Zhang
Yang Li
Jiazhen Liu
Xiaopeng Huo

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1541555

327 views

Original Research

Published on 30 May 2025

Association of neutrophil-percentage-to-albumin ratio with mortality in older stroke survivors

in Neuroinflammation and Neuropathy

Jie Huang
Xiaowei Zhang
Luyao Ding
Jiaxiang Yu
Mingshen Lin

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1611289

449 views

Original Research

Accepted on 29 May 2025

a-klotho as a biomarker of amyloid b levels in the cerebrospinal fluid

in Alzheimer's Disease and Related Dementias

Jacob Raber
Alexandra Pederson
Emily Bunnell
Nora Mattek
Nora Gray
Steven G. Kohama
Alison R Weiss
Joseph Quinn
Henryk F Urbanski

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1599402

199 views

Original Research

Accepted on 29 May 2025

Combined Association of Gait Speed and Processing Speed on Cardiometabolic Disease Mortality Risk in the US Older Adults: A Prospective Cohort Study from NHANES

in Neurocognitive Aging and Behavior

Hang Yang
Ye Zhou
Xiaoying Wang
Xiaoming Xu

Frontiers in Aging Neuroscience

doi 10.3389/fnagi.2025.1537413

202 views