Frontiers in Aging | Musculoskeletal Aging

Review

Accepted on 01 Sep 2025

The Role of Ferroptosis in Osteoporosis: From Pathogenic Mechanisms to Natural Product-Driven Therapeutic Innovations

in Musculoskeletal Aging

Yilin Zhu
Xing Wu
Xiao Peng
Hanwei He
Zheng Hu
Liangyi Xiao

Frontiers in Aging

doi 10.3389/fragi.2025.1654711

251 views

Original Research

Published on 18 Aug 2025

Risk factors and predictors of contralateral hip fracture after surgical treatment in elderly patients

in Musculoskeletal Aging

Huan Yang
Yusong Yuan
Ruidong Ge
Lei Shi
Fangda Si
Ying Chen

Frontiers in Aging

doi 10.3389/fragi.2025.1633184

810 views

Correction

Published on 31 Jul 2025

Correction: Age- and sex-related development of osteosarcopenia in the aging Octodon degus rodent model

in Musculoskeletal Aging

Pablo Gallo-Soljancic
Maria Egle De Stefano
Ana-Maria Lucas-Ochoa
Consuelo Sánchez-Rodrigo
Lorena Cuenca-Bermejo
Ana-María González-Cuello
Emiliano Fernández-Villalba
Maria-Trinidad Herrero

Frontiers in Aging

doi 10.3389/fragi.2025.1669031

740 views

Original Research

Published on 24 Jul 2025

Age-related gait adaptations: analysis of temporal gait parameters and variability, and muscle activation across flat vs. uneven surfaces in young, middle-aged, and older adults

in Musculoskeletal Aging

Thomas B. Inns
Ilaria Pina
Lewis James Macgregor
Paul A. Dudchenko
Rachel A. Crockett
Angus Murray Hunter

Frontiers in Aging

doi 10.3389/fragi.2025.1573778

1,464 views

Original Research

Published on 07 Jul 2025

Investigating the influence of mineral content changes on mechanical properties through ligament insertion

in Musculoskeletal Aging

Afif Gouissem
Fadi Alkhatib
Malek Adouni

Frontiers in Aging

doi 10.3389/fragi.2025.1556577

664 views

Mini Review

Published on 03 Jul 2025

Molecular constraints of sarcopenia in the ageing muscle

in Musculoskeletal Aging

S. Damanti
E. Senini
R. De Lorenzo
A. Merolla
S. Santoro
C. Festorazzi
M. Messina
G. Vitali
C. Sciorati
A. A. Manfredi

Frontiers in Aging

doi 10.3389/fragi.2025.1588014

3,040 views

Original Research

Published on 01 Jul 2025

Development and validation of a clinical prediction model for osteoporosis diagnosis by lumbosacral X-ray and radiomics

in Musculoskeletal Aging

Xiaofeng Chen
Dongling Cai
Hao Li
Weijun Guo
Qian Li
Jinjun Liang
Junxian Xie
Jincheng Liu
Zhen Xiang
Wenxuan Dong

Frontiers in Aging

doi 10.3389/fragi.2025.1476902

957 views

Original Research

Published on 27 Jun 2025

Radiomics based on lumbar CT to identify high-risk patients for OVCF in postmenopausal women

in Musculoskeletal Aging

Qingsong Yu
Huangda An
Jiabao Chen
Aoran Ding
Zhe Lu
Haidong Wang
Lei Ma

Frontiers in Aging

doi 10.3389/fragi.2025.1472060

995 views

Original Research

Published on 12 Jun 2025

Circulatory titin and miR-451a are possible sarcopenia biomarkers in elderly people

in Musculoskeletal Aging

Roberta Mancuso
Lorenzo Agostino Citterio
Simone Agostini
Rossella Miglioli
Riccardo Nuzzi
Laura Antolini
Fabio Trecate
Mario Clerici

Frontiers in Aging

doi 10.3389/fragi.2025.1587438

1,430 views

Original Research

Published on 10 Jun 2025

EI24 binds to IGF1R, enhancing glucose homeostasis and fostering healthy aging in male mice

in Musculoskeletal Aging

You-Min Kim
Seung Eon Lee
Yaechan Song
Tae Wook Nam
Jaehoon Lee
Je Kyung Seong
Wan Namkung
Han-Woong Lee

Frontiers in Aging

doi 10.3389/fragi.2025.1564730

1,418 views

Original Research

Published on 10 Jun 2025

Knowledge, attitude, and practice of osteoporosis prevention in elder patients following lumbar fusion surgery: a cross‐sectional study

in Musculoskeletal Aging

Shaoying Sheng
Manman Wang
Chengfei Yu
Qing Li
Zhan Wang
Yaojing Ma

Frontiers in Aging

doi 10.3389/fragi.2025.1543839

1,178 views

Original Research

Published on 27 May 2025

Bioelectrical impedance vectors analysis (BIVA) in older adults according to level of physical activity and muscle strength: a comparison of classic and specific approaches

in Musculoskeletal Aging

Ismael Figueiredo Rabelo
Shannon Farrell
Kieran F. Reid
Vanessa Ribeiro Dos Santos
Melissa Antunes
Vitor Cabrera Batista
Andreia Bauermann-Vieira
Luís Alberto Gobbo

Frontiers in Aging

doi 10.3389/fragi.2025.1535876

1,644 views

Original Research

Published on 08 May 2025

Menopause-related changes to maxillary trabecular bone micro-architecture

in Musculoskeletal Aging

Alexandra Stein
Michael Levit
Hammaad Shah
Michael Yin
Sunil Wadhwa

Frontiers in Aging

doi 10.3389/fragi.2025.1589708

1,551 views

Original Research

Published on 25 Apr 2025

Validity and reliability of Gripwise digital dynamometer in the assessment of handgrip strength in older adults

in Musculoskeletal Aging

Gabriela Benatti de Oliveira
Lara Vilar Fernandes
Teresa F. Amaral
Ana Carolina Junqueira Vasques
Ligiana Pires Corona

Frontiers in Aging

doi 10.3389/fragi.2025.1560097

1,809 views

Original Research

Published on 22 Apr 2025

A comparative analysis of binary and multi-class classification machine learning algorithms to detect current frailty status using the English longitudinal study of ageing (ELSA)

in Musculoskeletal Aging

Charmayne Mary Lee Hughes
Yan Zhang
Ali Pourhossein
Terezia Jurasova

Frontiers in Aging

doi 10.3389/fragi.2025.1501168

2,348 views
1 citation

Original Research

Published on 24 Mar 2025

The relationship between hearing loss and frailty in older adults at risk of cognitive decline: a cross-sectional study

in Musculoskeletal Aging

Rong Tian
Osvaldo P. Almeida
Andrew H. Ford
Leon Flicker
Nicola T. Lautenschlager
Suzanne Robinson
Marshall Makate
Simone Pettigrew
Sin Huey Lee
Ina Dorsheimer

Frontiers in Aging

doi 10.3389/fragi.2025.1524186

2,032 views