ORIGINAL RESEARCH article
Front. Allergy
Sec. Asthma
Actual use of PROMs in Asthma and Rhinitis recommended by guidelines in clinical settings: PROMUSE Respiratory Study
Iván Cherrez-Ojeda 1,2
Jean J Bousquet 1,2
Torsten Zuberbier 1,2
Juan C. Calderon 3,4
Pavel Kolkhir 1,2
Anastasiia Allenova 5
Andrey Allenov 6,7,8
Sergey Tkachenko 9
Mihaltan Florin 10
Ulmeanu Ruxandra 10
Mona Al-Ahmad 11,12
MONICA RODRIGUEZ-GONZALEZ 13
Guillermo Wakida-Kusunoki 14
German Dario Ramon 15
Maia Rukhadze 16
Désirée E. Larenas-Linnemann 17
Mitja Kosnik 18
Juan Carlos Ivancevich 19
LUIS FELIPE ENSINA 20
Nelson Augusto Rosario Filho 21
Violeta Kvedariene 22
Herberto Jose Chong-Neto 21
Ivan Tinoco 23
Anna Bedbrook 24
Gabriela Rodas-Valero 3,4
Marco Faytong-Haro 25,26
Marcus Maurer 1,2
Oliver Pfaar 27
Karla Robles-Velasco 3,4
1. Charité – Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, and Humboldt-Universität zu Berlin, Berlin, Germany
2. Fraunhofer-Institut fur Translationale Medizin und Pharmakologie ITMP, Frankfurt, Germany
3. Universidad de Especialidades Espiritu Santo, Samborondon, Ecuador
4. Respiralab Research Group, Guayaquil, Ecuador
5. The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China
6. Pervyj Moskovskij gosudarstvennyj medicinskij universitet imeni I M Secenova Fakul'tet dovuzovskogo obrazovania, Moscow, Russia
7. 7 State Budgetary Healthcare Institution of the City of Moscow "City Polyclinic No. 210 of the Department of Health of the City of Moscow", Moscow, Russia
8. Federal State Budgetary Scientific Institution “N.A. Semashko National Research Institute of Public Health", Moscow, Russia
9. Russian Medical Academy of Сontinuous Professional Education of the Ministry of Health of the Russian Federation, Moscow, Russia
10. Institutul de Pneumoftiziologie Marius Nasta, Bucharest, Romania
11. Kuwait University Faculty of Medicine, Safat, Kuwait
12. Al-Rashed Allergy Center, Ministry of Health, Kuwait, Kuwait
13. Hospital Espanol, Mexico City, Mexico
14. Colegio Mexicano de Pediatras Especialistes en Inmunologia Clinica y Alergia AC, Distrito Federal, Mexico
15. Hospital Italiano de Buenos Aires, Buenos Aires, Argentina
16. Tbilisi David Agmasenebeli Teaching University, Tbilisi, Georgia
17. Medica Sur, Mexico City, Mexico
18. Univerzitetna klinika za pljucne bolezni in alergijo Golnik, Golnik, Slovenia
19. Servicio de Alergia e Immunologia Clinica Santa Isabel Buenos Aires, Buenos Aires, Argentina
20. Universidade Federal de Sao Paulo Disciplina de Alergia Imunologia Clinica e Reumatologia, São Paulo, Brazil
21. Universidade Federal do Parana Departamento de Pediatria, Curitiba, Brazil
22. Vilniaus universitetas Medicinos fakultetas, Vilnius, Lithuania
23. Centro de Alergia Tinoco, Machala, Ecuador
24. MASK-air SAS, Montpellier, France
25. Universidad Estatal de Milagro, Milagro, Ecuador
26. Ecuadorian Development Research Lab, Daule, Ecuador
27. Philipps-Universitat Marburg, Marburg, Germany
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Abstract
Rationale: Guidelines advise for the implementation of patient-reported outcomes (PROMs) to provide crucial insights into patients' perceptions of their disease burden, treatment needs, and quality of life. Despite their proven benefits in managing chronic respiratory diseases like asthma, allergic rhinitis (AR), and rhinosinusitis (RS), there is limited data on their adoption among physicians treating these conditions. Objectives: Our objective is to identify the utilization patterns of PROMs, together with the reasons for their usage and the barriers to their adoption among practitioners managing patients with asthma, AR, and RS. Methods: This was a cross-sectional observational study using a questionnaire encompassing all pertinent PROMs and disseminated to practitioners associated with the ARIA, UCARE, ADCARE, and ACARE networks. Individuals unfamiliar with PROMS or lacking prior experience with it were eliminated. Descriptive and analytical data were utilized, categorized by the frequency and type of PROMs applied. Stata 18.0 was utilized, with p<0.05 indicating statistical significance. Results: A total of 439 practitioners participated, with PROMs predominantly utilized by physicians certified for over 30 years and by respiratory specialists (16.67% and 12.46%, respectively; p<0.05). Pulmonologists exhibited the greatest utilization of asthma PROMs at 86%, while allergists predominantly employed AR and RS PROMs at 38.42% and 33.33%, respectively (p < 0.001). ACT (66.74%), RCAT (27.79%), and SNOTT22 (15.26%) were the predominant PROMs utilized primarily for asthma (79.19%), AR (51.23%), and RS (57.26%), respectively (p<0.001). The foremost purposes for their application were disease control monitoring (93.39%) and evaluation of performance of therapy approaches (90.2%). The most significant barrier identified was time constraint, rated at 75.40% (p>0.05 across all groups). Conclusions: The use of PROMs is suboptimal, primarily due to time limitations. It is imperative that methods be swiftly implemented to include these techniques into the therapeutic environment to attain enhanced outcomes.
Summary
Keywords
allergic rhinitis, Asthma, Patient reported outcome measures, Physicians, rhinosinusitis
Received
15 July 2025
Accepted
31 January 2026
Copyright
© 2026 Cherrez-Ojeda, Bousquet, Zuberbier, Calderon, Kolkhir, Allenova, Allenov, Tkachenko, Florin, Ruxandra, Al-Ahmad, RODRIGUEZ-GONZALEZ, Wakida-Kusunoki, Ramon, Rukhadze, Larenas-Linnemann, Kosnik, Ivancevich, ENSINA, Augusto Rosario Filho, Kvedariene, Chong-Neto, Tinoco, Bedbrook, Rodas-Valero, Faytong-Haro, Maurer, Pfaar and Robles-Velasco. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
*Correspondence: Iván Cherrez-Ojeda
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