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METHODS article

Front. Artif. Intell.

Sec. Machine Learning and Artificial Intelligence

This article is part of the Research TopicFrontiers in Explainable AI: Positioning XAI for Action, Human-Centered Design, Ethics, and UsabilityView all 5 articles

Implementing physics-informed neural networks with Deep Learning for Differential Equations

Provisionally accepted
  • 1Tampereen yliopisto - Hervannan kampus, Tampere, Finland
  • 2University of Applied Sciences Upper Austria, Wels, Austria
  • 3Technische Universitat Graz, Graz, Austria

The final, formatted version of the article will be published soon.

Physics-aware machine learning integrates domain-specific physical knowledge into machine learning models, leading to the development of physics-informed neural networks (PINNs). PINNs embed physical laws directly into the learning process, enabling interpretable and physically consistent solutions to complex problems. However, the practical use of PINNs presents challenges and their applications are complex. Therefore, in this paper, we demonstrate the implementation of PINNs for systems of ordinary differential equations (ODEs), an area that is often overlooked by the physics community, which typically focuses on partial differential equations. We discuss two key challenges: the inverse problem, which involves estimating unknown parameters of ODEs, and the forward problem, which provides an approximate solution to ODEs. To provide practical insights into PINNs, we present two case studies based on a Python implementation using DeepXDE. Drawing on these studies, we discuss key challenges and identify promising directions for future research in PINN-based implementation frameworks.

Keywords: Data-Driven Scientific Machine Learning, Forward problem, inverse problem, OrdinaryDifferential Equation, Physics Aware Machine Learning, Physics-informed neural network

Received: 01 Oct 2025; Accepted: 19 Jan 2026.

Copyright: © 2026 Emmert-Streib, Tripathi, Farea and Holzinger. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

* Correspondence: Shailesh Tripathi

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