REVIEW article
Front. Bioeng. Biotechnol.
Sec. Nanobiotechnology
Volume 13 - 2025 | doi: 10.3389/fbioe.2025.1569889
This article is part of the Research TopicThe Role of Nanostructured Materials in Targeted Drug DeliveryView all 3 articles
Ginger-derived exosome-like nanoparticles: a representative of plant-based natural nanostructured drug delivery system
Provisionally accepted
- 1College of medicine, Linyi University, Linyi, China
- 2Clinical Medical College and The First Affiliated Hospital of Chengdu Medical College, Chengdu, China
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In recent years, the research on plant-derived exosome-like nanoparticles (PELNs) has attracted increasing attention. Among these, ginger-derived exosome-like nanoparticles (GELNs) stand out due to their specific pharmacological activity and their role as reliable carriers for delivering both hydrophilic and hydrophobic drugs, as well as small RNAs, making them a noteworthy representative of plant-based natural nanostructured drug delivery systems (DDS). In this review, we first introduce the characteristics and engineering methods of GELN-based DDS to brush up on our current understanding and then focus on research progress to summarize their therapeutic application scope and challenges.
Keywords: plant-derived exosome-like nanoparticles, Ginger, ginger-derived exosome-like nanoparticles, drug delivery system, Intestinal Diseases
Received: 02 Feb 2025; Accepted: 26 May 2025.
Copyright: © 2025 Liu, Deng, Li, Lin, Liu, Yang, Zhou and Jiang. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence:
Zunzhen Zhou, Clinical Medical College and The First Affiliated Hospital of Chengdu Medical College, Chengdu, China
Yuan Jiang, Clinical Medical College and The First Affiliated Hospital of Chengdu Medical College, Chengdu, China
Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.