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ORIGINAL RESEARCH article

Front. Bioeng. Biotechnol.

Sec. Biosensors and Biomolecular Electronics

Volume 13 - 2025 | doi: 10.3389/fbioe.2025.1572970

Development and In-Vitro Validation of an Intraoral Wearable Biofeedback System for Bruxism Management

Provisionally accepted
Khalid  Al-HamadKhalid Al-Hamad1*Ashwaq  AsiriAshwaq Asiri2Ali  M Al-QahtaniAli M Al-Qahtani3Saud  AlotaibiSaud Alotaibi4Abdullah  AlmalkiAbdullah Almalki4
  • 1Department of Maxillofacial, and Diagnostic Sciences, College of Dentistry,Majmaah Unversity, Majmaah,11952, Saudi Arabia
  • 2Department of Restorative Dental Sciences, College of Dentistry, Majmaah University, Al-Majmaah 11952, Saudi Arabia
  • 3Department of Diagnostic Sciences and Oral Biology, College of Dentistry, King Khalid University, Abha, Saudi Arabia
  • 4Department of Preventive Dental Sciences, College of Dentistry, Majmaah University, Majmaah, 11952, Saudi Arabia

The final, formatted version of the article will be published soon.

Introduction: Bruxism remains a diagnostic challenge, with no consistently reliable clinical approaches available to document the condition with satisfactory accuracy. This study aimed to incorporate a biosensor device into a conventional bite-night guard to detect bruxism in an in vitro setting. Methods: A sandwich-layering process was used to integrate stress and vibration sensors into an acrylic occlusal stabilization splint. The system included a microcontroller, control unit, and data acquisition module. Occlusal force signals were processed using artificial intelligence-based algorithms. A total of 200 repeated trials were conducted to evaluate system performance. Accuracy, sensitivity, and specificity were calculated as validation metrics. Results: The biosensor prototype demonstrated reliable performance across a force range of 274–700 N. Quantitative evaluation of the neural network yielded an accuracy of 91%, sensitivity of 88%, and specificity of 90% in distinguishing occlusal force thresholds. Conclusion: The findings confirm the feasibility of integrating biosensors within an intraoral appliance for bruxism detection in vitro. Future research should explore long-term durability testing in moist environments and conduct in vivo trials to validate clinical performance.

Keywords: Bite Nightguard, Oral appliances, Bruxism detection, dental health, Occlusal splint, occlusion, Biosensor technology, biofeedback

Received: 11 Feb 2025; Accepted: 02 Oct 2025.

Copyright: © 2025 Al-Hamad, Asiri, Al-Qahtani, Alotaibi and Almalki. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

* Correspondence: Khalid Al-Hamad, ka.alhamad@mu.edu.sa

Disclaimer: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.