REVIEW article
Front. Bioeng. Biotechnol.
Sec. Nanobiotechnology
Volume 13 - 2025 | doi: 10.3389/fbioe.2025.1621876
This article is part of the Research TopicAdvancements in microbial engineering for natural product synthesisView all articles
Sustainable production of Microalgal Nanoparticles through Green Synthesis towards CancerTreatment
Provisionally accepted
Vijay Kumar Garlapati1*
Swati Sharma1
Deepak Sharma1
S Prashant Jeevan Kumar2
Samuel Jacob3
Arindam Kuila4
Ashok Kumar Gupta1Abhishek Chaudhary1- 1Jaypee University of Information Technology, Waknaghat, India
- 2ICAR-Directorate of Floricultural Research, Pune, India
- 3SRM Institute of Science and Technology, Kattankulathur, India
- 4Banasthali Vidyapith, Tonk, India
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Nanoparticle-based treatment is one of the rapidly growing research domains in cancer treatment due to its associated structural, targeted, and stability features. The conventional (chemical and physical) nanoparticle (NP) synthesis suffers from drawbacks such as toxicity, cost, and unsustainable process methodologies, which necessitate the urgent need for sustainable green approaches to nanoparticle synthesis for envisioned cancer treatment options. The green synthesis of microalgal NPs is a promising approach for obtaining NPs for cancer treatment. As a result, this review presents the synthesis mechanism of microalgal NPs and the factors affecting their green synthesis. The mechanism of action of microalgal NPs in cancer treatment has been discussed in relation to their cytotoxic effects. The sustainability features, probable quality control regime of green-synthesized microlgal NPs, along with the prospects of incorporating synthetic biology and utilizing genetically engineered microalgae, have been highlighted in the context of cancer treatment.
Keywords: Green synthesis, Microalgal nanoparicles, sustainability, cancer treatment, Future prospective
Received: 12 May 2025; Accepted: 28 Aug 2025.
Copyright: © 2025 Garlapati, Sharma, Sharma, Kumar, Jacob, Kuila, Gupta and Chaudhary. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence: Vijay Kumar Garlapati, Jaypee University of Information Technology, Waknaghat, India
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