ORIGINAL RESEARCH article
Front. Bioeng. Biotechnol.
Sec. Biomechanics
Volume 13 - 2025 | doi: 10.3389/fbioe.2025.1626645
Computational Investigation on Total Cavo-Pulmonary Connection Circulation Assisted by An Axial Flow Pump
Provisionally accepted
- 1Anzhen hospital, Beijing, China
- 2Fudan University, Shanghai, China
- 3Yiwu Research Institute of Fudan University, Yiwu, China
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This study employed computational fluid dynamics (CFD) to explore the power assistance effect of axial flow blood pump when it was virtually implanted in the real TCPC structure of Fontan patients and analyze the differences between constant speed pumps and variable speed pumps. The numerical simulation results show that the implantation of the blood pump increases pulmonary circulation blood flow by 32.6%, significantly improving the uneven distribution of flow in the left and right pulmonary arteries (the left/right pulmonary artery flow ratio is improved from 1:1.8 to 1:1.2). The constant speed pump mode increases hepatic venous return flow by 19.4% compared to baseline conditions, while the variable speed pump only improves by 12.7%. The constant speed pump generates a more stable spiral flow pattern in the TCPC structure, reducing energy loss by 21.3% compared to the variable speed pump, and the wall shear stress distribution in the inferior vena cava region is closer to physiological conditions. This study confirms that the constant speed mode in powered Fontan circulation has significant advantages in maintaining blood flow stability, optimizing energy efficiency, and promoting organspecific venous return.
Keywords: Fontan surgery, Total cavopulmonary connection, Axial flow blood pump, computational fluid dynamics, Patient specific
Received: 11 May 2025; Accepted: 14 Jul 2025.
Copyright: © 2025 Jin, Liu, Wu, Wang and Zhu. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence:
Shengzhang Wang, Fudan University, Shanghai, China
JunMing Zhu, Anzhen hospital, Beijing, China
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