REVIEW article
Front. Bioeng. Biotechnol.
Sec. Biomaterials
Volume 13 - 2025 | doi: 10.3389/fbioe.2025.1640682
This article is part of the Research TopicAdvances in Polymer-Based Biomaterials for Tissue Engineering and Regenerative MedicineView all 6 articles
Research on the Mechanisms of Natural Products in Radiation Protection
Provisionally accepted
- 1Shanghai Ocean University, Shanghai, China
- 2Navy Special Medical Centre, Shanghai, China
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1. Systematically summarize the multilevel damage mechanisms of ionizing radiation in biological systems, and illustrate the process using intuitive diagrams.2. Comprehensively summarize recent advances in anti-radiation natural drugs and bioactive monomers, classifying them by structural characteristics. 3. Under the classification framework of five types of natural radiation-resistant components (polysaccharides, polyphenols, saponins, alkaloids, and polypeptides), the mechanism of action of the five types of natural radiation-resistant components (polysaccharides, polyphenols, saponins, alkaloids, and polypeptides) was analyzed in depth. 4. Combined with modern radiotherapy programs and cutting-edge research trends, the development strategy of a new generation of radiation protective agents based on natural products is proposed; By elucidating the targeting mechanism and action bias of various natural compounds, the transformation prospect of various natural compounds in the field of highefficiency and low-toxicity radiation protection is demonstrated.
Keywords: Ionizing radiation, radiation damage, Natural Products, Preventive and therapeutic effect, Mechanism
Received: 04 Jun 2025; Accepted: 07 Aug 2025.
Copyright: © 2025 Li, Yu, Xu, Xing, Huiwu, Zhou, Li and He. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence:
Zheng Zhou, Navy Special Medical Centre, Shanghai, China
Bailin Li, Shanghai Ocean University, Shanghai, China
Ying He, Navy Special Medical Centre, Shanghai, China
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