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POLICY AND PRACTICE REVIEWS article

Front. Bioeng. Biotechnol.

Sec. Industrial Biotechnology

Volume 13 - 2025 | doi: 10.3389/fbioe.2025.1681476

Establishing BioE3 Centres: Catalyzing India's Biomanufacturing Transformation

Provisionally accepted
Dhiraj  KumarDhiraj Kumar*Jitendra  KumarJitendra Kumar
  • Biotechnology Industry Research Assistance Council (BIRAC), New Delhi, India

The final, formatted version of the article will be published soon.

India's bioeconomy is poised for rapid expansion, targeting a valuation of $300 billion by 2030. The recently approved BioE3 Policy (Biotechnology for Economy, Environment, and Employment) aims to reposition India as a global leader in sustainable, high-performance biomanufacturing [1]. In this context, a national stakeholder meeting was convened to discuss the operationalization of BioE3 Centres— new-generation incubation and biomanufacturing hubs aimed at bridging the critical infrastructure and capability gaps. a national stakeholder meeting was convened with ~75 participants, including CEOs, COOs, and senior representatives from bioincubators, Centres of Excellence, startups, and scientific institutions. Structured group discussions and expert inputs focused on operationalizing BioE3 Centres— new-generation incubation and biomanufacturing hubs aimed at bridging critical infrastructure and capability gaps]. Discussions identified the need for pilot-scale infrastructure, regulatory-grade facilities, skilled human resources, and integration with existing policy mechanisms such as the Biotechnology Industry Partnership Programme (BIPP) and the Entrepreneur-in-Residence (EIR) initiative under BIRAC [2]. Once fully operational, BioE3 Centres are projected to support over 250 startups and MSMEs, generate an estimated 10,000 skilled jobs, and contribute up to $25 billion to India's targeted $300 billion bioeconomy by 2030. This article outlines the key insights, recommendations, and phased implementation roadmap from the consultation, with implications for national policy execution and global positioning of India's bioeconomy bioinnovation infrastructure planning [3,4].

Keywords: BioE3 Policy, Biomanufacturing, Biotechnology Infrastructure, Translational Innovation, bioeconomy, BIRAC, Policy implementation, India

Received: 07 Aug 2025; Accepted: 29 Aug 2025.

Copyright: © 2025 Kumar and Kumar. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

* Correspondence: Dhiraj Kumar, Biotechnology Industry Research Assistance Council (BIRAC), New Delhi, India

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