Frontiers in Bioengineering and Biotechnology | Tissue Engineering and Regenerative Medicine

Original Research

Published on 03 Jun 2020

Induction of in vitro Metabolic Zonation in Primary Hepatocytes Requires Both Near-Physiological Oxygen Concentration and Flux

in Tissue Engineering and Regenerative Medicine

Benedikt Scheidecker
Marie Shinohara
Masahiro Sugimoto
Mathieu Danoy
Masaki Nishikawa
Yasuyuki Sakai

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2020.00524

7,627 views
29 citations

Original Research

Published on 29 May 2020

Promoted Viability and Differentiated Phenotype of Cultured Chondrocytes With Low Level Laser Irradiation Potentiate Efficacious Cells for Therapeutics

in Tissue Engineering and Regenerative Medicine

Xiaohong Yang
Timon Chengyi Liu
Shaojie Liu
Weicong Zhu
Honglin Li
Peihong Liang
Suihui Ye
Shuliang Cui

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2020.00468

5,170 views
11 citations

Review

Published on 27 May 2020

Toward Cardiac Regeneration: Combination of Pluripotent Stem Cell-Based Therapies and Bioengineering Strategies

in Tissue Engineering and Regenerative Medicine

Marta Mazzola
Elisa Di Pasquale

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2020.00455

16,125 views
63 citations

Original Research

Published on 26 May 2020

Optimizing an Injectable Composite Oxygen-Generating System for Relieving Tissue Hypoxia

in Tissue Engineering and Regenerative Medicine

Tai-En Hsieh
Sheng-Ju Lin
Li-Chi Chen
Chun-Chieh Chen
Po-Liang Lai
Chieh-Cheng Huang

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2020.00511

7,090 views
28 citations

Original Research

Published on 25 May 2020

Hybrid Bioprinting of Chondrogenically Induced Human Mesenchymal Stem Cell Spheroids

in Tissue Engineering and Regenerative Medicine

Lise De Moor
Sélina Fernandez
Chris Vercruysse
Liesbeth Tytgat
Mahtab Asadian
Nathalie De Geyter
Sandra Van Vlierberghe
Peter Dubruel
Heidi Declercq

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2020.00484

15,197 views
93 citations

Original Research

Published on 25 May 2020

Tissue Engineered Axon Tracts Serve as Living Scaffolds to Accelerate Axonal Regeneration and Functional Recovery Following Peripheral Nerve Injury in Rats

in Tissue Engineering and Regenerative Medicine

Kritika S. Katiyar
Laura A. Struzyna
Joseph P. Morand
Justin C. Burrell
Basak Clements
Franco A. Laimo
Kevin D. Browne
Joachim Kohn
Zarina Ali
Harry C. Ledebur

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2020.00492

7,571 views
33 citations

Review

Published on 21 May 2020

Natural Polymeric Scaffolds in Bone Regeneration

in Tissue Engineering and Regenerative Medicine

Miriam Filippi
Gordian Born
Mansoor Chaaban
Arnaud Scherberich

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2020.00474

45,548 views
330 citations

Original Research

Published on 19 May 2020

Hybrid Injectable Sol-Gel Systems Based on Thermo-Sensitive Polyurethane Hydrogels Carrying pH-Sensitive Mesoporous Silica Nanoparticles for the Controlled and Triggered Release of Therapeutic Agents

in Tissue Engineering and Regenerative Medicine

Monica Boffito
Alessandro Torchio
Chiara Tonda-Turo
Rossella Laurano
Miguel Gisbert-Garzarán
Julia C. Berkmann
Claudio Cassino
Miguel Manzano
Georg N. Duda
María Vallet-Regí

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2020.00384

10,141 views
29 citations

Original Research

Published on 15 May 2020

Optimisation of a Novel Bio-Substrate as a Treatment for Atrophic Age-Related Macular Degeneration

in Tissue Engineering and Regenerative Medicine

Rachel McCormick
Ian Pearce
Stephen Kaye
Atikah Haneef

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2020.00456

7,779 views
9 citations

Original Research

Published on 14 May 2020

Elastin-Like Recombinamer Hydrogels for Improved Skeletal Muscle Healing Through Modulation of Macrophage Polarization

in Tissue Engineering and Regenerative Medicine

Arturo Ibáñez-Fonseca
Silvia Santiago Maniega
Darya Gorbenko del Blanco
Benedicta Catalán Bernardos
Aurelio Vega Castrillo
Ángel José Álvarez Barcia
Matilde Alonso
Héctor J. Aguado
José Carlos Rodríguez-Cabello

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2020.00413

7,877 views
41 citations

Review

Published on 13 May 2020

Young at Heart: Combining Strategies to Rejuvenate Endogenous Mechanisms of Cardiac Repair

in Tissue Engineering and Regenerative Medicine

Edoardo Maghin
Patrizia Garbati
Rodolfo Quarto
Martina Piccoli
Sveva Bollini

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2020.00447

7,836 views
19 citations

Original Research

Published on 08 May 2020

Improvement of a Three-Layered in vitro Skin Model for Topical Application of Irritating Substances

in Tissue Engineering and Regenerative Medicine

Freia F. Schmidt
Sophia Nowakowski
Petra J. Kluger

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2020.00388

22,886 views
56 citations

Original Research

Published on 05 May 2020

Development of a New 3D Hybrid Model for Epithelia Morphogenesis

in Tissue Engineering and Regenerative Medicine

Filippos Ioannou
Malik A. Dawi
Robert J. Tetley
Yanlan Mao
José J. Muñoz

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2020.00405

6,374 views
28 citations

Original Research

Published on 05 May 2020

Microfluidic Biofabrication of 3D Multicellular Spheroids by Modulation of Non-geometrical Parameters

in Tissue Engineering and Regenerative Medicine

Silvia Lopa
Francesco Piraino
Giuseppe Talò
Valerio Luca Mainardi
Simone Bersini
Margherita Pierro
Luigi Zagra
Marco Rasponi
Matteo Moretti

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2020.00366

6,679 views
16 citations

Original Research

Published on 05 May 2020

Aged Tendon Stem/Progenitor Cells Are Less Competent to Form 3D Tendon Organoids Due to Cell Autonomous and Matrix Production Deficits

in Tissue Engineering and Regenerative Medicine

Zexing Yan
Heyong Yin
Christoph Brochhausen
Christian G. Pfeifer
Volker Alt
Denitsa Docheva

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2020.00406

7,629 views
43 citations

Original Research

Published on 30 Apr 2020

Tripolyphosphate-Crosslinked Chitosan/Gelatin Biocomposite Ink for 3D Printing of Uniaxial Scaffolds

in Tissue Engineering and Regenerative Medicine

Tiziana Fischetti
Nehar Celikkin
Nicola Contessi Negrini
Silvia Farè
Wojciech Swieszkowski

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2020.00400

18,561 views
76 citations

Original Research

Published on 29 Apr 2020

Computational Modeling of Human Mesenchymal Stromal Cell Proliferation and Extra-Cellular Matrix Production in 3D Porous Scaffolds in a Perfusion Bioreactor: The Effect of Growth Factors

in Tissue Engineering and Regenerative Medicine

Mohammad Mehrian
Toon Lambrechts
Ioannis Papantoniou
Liesbet Geris

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2020.00376

6,731 views
17 citations

Original Research

Published on 24 Apr 2020

A Novel Scaffold-Based Hybrid Multicellular Model for Pancreatic Ductal Adenocarcinoma—Toward a Better Mimicry of the in vivo Tumor Microenvironment

in Tissue Engineering and Regenerative Medicine

Priyanka Gupta
Pedro A. Pérez-Mancera
Hemant Kocher
Andrew Nisbet
Giuseppe Schettino
Eirini G. Velliou

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2020.00290

10,482 views
51 citations

Original Research

Published on 24 Apr 2020

Primary Human Osteoblasts Cultured in a 3D Microenvironment Create a Unique Representative Model of Their Differentiation Into Osteocytes

in Tissue Engineering and Regenerative Medicine

Gabriele Nasello
Pilar Alamán-Díez
Jessica Schiavi
María Ángeles Pérez
Laoise McNamara
José Manuel García-Aznar

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2020.00336

16,446 views
71 citations

Original Research

Published on 21 Apr 2020

Cell-Laden Agarose-Collagen Composite Hydrogels for Mechanotransduction Studies

in Tissue Engineering and Regenerative Medicine

Elena Cambria
Silvio Brunner
Sally Heusser
Philipp Fisch
Wolfgang Hitzl
Stephen J. Ferguson
Karin Wuertz-Kozak

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2020.00346

15,888 views
68 citations

Original Research

Published on 17 Apr 2020

Tissue Engineering Using Vascular Organoids From Human Pluripotent Stem Cell Derived Mural Cell Phenotypes

in Tissue Engineering and Regenerative Medicine

Maria Markou
Dimitrios Kouroupis
Fotios Badounas
Athanasios Katsouras
Athena Kyrkou
Theodore Fotsis
Carol Murphy
Eleni Bagli

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2020.00278

15,999 views
28 citations

Mini Review

Published on 17 Apr 2020

Therapeutic Potential of Extracellular Vesicles in Degenerative Diseases of the Intervertebral Disc

in Tissue Engineering and Regenerative Medicine

Nathan Piazza
Mehdi Dehghani
Thomas R. Gaborski
Karin Wuertz-Kozak

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2020.00311

8,637 views
41 citations

Original Research

Published on 17 Apr 2020

Sequential Delivery of Cryogel Released Growth Factors and Cytokines Accelerates Wound Healing and Improves Tissue Regeneration

in Tissue Engineering and Regenerative Medicine

Shiro Jimi
Alexandr Jaguparov
Ayan Nurkesh
Bolat Sultankulov
Arman Saparov

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2020.00345

9,245 views
63 citations

Original Research

Published on 17 Apr 2020

Angiogenic Potential of Tissue Engineered Cartilage From Human Mesenchymal Stem Cells Is Modulated by Indian Hedgehog and Serpin E1

in Tissue Engineering and Regenerative Medicine

Yannick Nossin
Eric Farrell
Wendy J. L. M. Koevoet
Rodrigo A. Somoza
Arnold I. Caplan
Bent Brachvogel
Gerjo J. V. M. van Osch

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2020.00327

5,781 views
17 citations