Frontiers in Bioengineering and Biotechnology | Tissue Engineering and Regenerative Medicine

Review

Published on 28 Feb 2020

Five Decades Later, Are Mesenchymal Stem Cells Still Relevant?

in Tissue Engineering and Regenerative Medicine

Mario Gomez-Salazar
Zaniah N. Gonzalez-Galofre
Joan Casamitjana
Mihaela Crisan
Aaron W. James
Bruno Péault

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2020.00148

44,777 views
137 citations

Original Research

Published on 21 Feb 2020

Thermal Bioprinting Causes Ample Alterations of Expression of LUCAT1, IL6, CCL26, and NRN1L Genes and Massive Phosphorylation of Critical Oncogenic Drug Resistance Pathways in Breast Cancer Cells

in Tissue Engineering and Regenerative Medicine

Aleli Campbell
Jonathon E. Mohl
Denisse A. Gutierrez
Armando Varela-Ramirez
Thomas Boland

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2020.00082

6,294 views
31 citations

Original Research

Published on 21 Feb 2020

Two-Dimensional Cellular and Three-Dimensional Bio-Printed Skin Models to Screen Topical-Use Compounds for Irritation Potential

in Tissue Engineering and Regenerative Medicine

Zhengxi Wei
Xue Liu
Masato Ooka
Li Zhang
Min Jae Song
Ruili Huang
Nicole C. Kleinstreuer
Anton Simeonov
Menghang Xia
Marc Ferrer

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2020.00109

12,642 views
44 citations

Original Research

Published on 21 Feb 2020

Auto Micro Atomization Delivery of Human Epidermal Organoids Improves Therapeutic Effects for Skin Wound Healing

in Tissue Engineering and Regenerative Medicine

Mingyang Chang
Juan Liu
Baolin Guo
Xin Fang
Yi Wang
Shuyong Wang
Xiaofang Liu
Lola M. Reid
Yunfang Wang

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2020.00110

9,287 views
13 citations

Review

Published on 21 Feb 2020

Lung Microvascular Niche, Repair, and Engineering

in Tissue Engineering and Regenerative Medicine

Tomoshi Tsuchiya
Ryoichiro Doi
Tomohiro Obata
Go Hatachi
Takeshi Nagayasu

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2020.00105

15,541 views
42 citations

Original Research

Published on 19 Feb 2020

Multiparametric Optical Bioimaging Reveals the Fate of Epoxy Crosslinked Biomeshes in the Mouse Subcutaneous Implantation Model

in Tissue Engineering and Regenerative Medicine

Vadim Elagin
Daria Kuznetsova
Ekaterina Grebenik
Denis A. Zolotov
Leonid Istranov
Tatiana Zharikova
Elena Istranova
Anastasia Polozova
Dmitry Reunov
Alexandr Kurkov

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2020.00107

4,592 views
18 citations

Review

Published on 18 Feb 2020

In situ Enabling Approaches for Tissue Regeneration: Current Challenges and New Developments

in Tissue Engineering and Regenerative Medicine

Juliana R. Dias
Nilza Ribeiro
Sara Baptista-Silva
Ana Rita Costa-Pinto
Nuno Alves
Ana L. Oliveira

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2020.00085

14,309 views
54 citations

Review

Published on 18 Feb 2020

Electrospun Polymers in Cartilage Engineering—State of Play

in Tissue Engineering and Regenerative Medicine

Elif Nur Yilmaz
Dimitrios I. Zeugolis

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2020.00077

9,996 views
42 citations

Original Research

Published on 14 Feb 2020

The Secretome Derived From Mesenchymal Stromal Cells Cultured in a Xeno-Free Medium Promotes Human Cartilage Recovery in vitro

in Tissue Engineering and Regenerative Medicine

Maria Elisabetta Federica Palamà
Georgina Margaret Shaw
Simonetta Carluccio
Daniele Reverberi
Laura Sercia
Luana Persano
Dario Pisignano
Katia Cortese
Francis Peter Barry
Josephine Mary Murphy

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2020.00090

7,820 views
31 citations

Original Research

Published on 14 Feb 2020

Influence of the Fabrication Accuracy of Hot-Embossed PCL Scaffolds on Cell Growths

in Tissue Engineering and Regenerative Medicine

Tania Limongi
Elisabetta Dattola
Cirino Botta
Maria Laura Coluccio
Patrizio Candeloro
Maria Cucè
Bernadette Scopacasa
Maria Eugenia Gallo Cantafio
Costantino Davide Critello
Salvatore Andrea Pullano

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2020.00084

4,219 views
7 citations

Correction

Published on 04 Feb 2020

Corrigendum: Bioengineered Platforms for Chronic Wound Infection Studies: How Can We Make Them More Human-Relevant?

in Tissue Engineering and Regenerative Medicine

Snehal Kadam
Shivani Nadkarni
Janhavi Lele
Savani Sakhalkar
Pratiksha Mokashi
Karishma Surendra Kaushik

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2019.00449

2,729 views

Review

Published on 29 Jan 2020

Optogenetics: Background, Methodological Advances and Potential Applications for Cardiovascular Research and Medicine

in Tissue Engineering and Regenerative Medicine

Jyotsna Joshi
Michael Rubart
Wuqiang Zhu

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2019.00466

88,985 views
95 citations

Original Research

Published on 29 Jan 2020

A Self-Setting Hydrogel of Silylated Chitosan and Cellulose for the Repair of Osteochondral Defects: From in vitro Characterization to Preclinical Evaluation in Dogs

in Tissue Engineering and Regenerative Medicine

Cécile Boyer
Gildas Réthoré
Pierre Weiss
Cyril d’Arros
Julie Lesoeur
Claire Vinatier
Boris Halgand
Olivier Geffroy
Marion Fusellier
Gildas Vaillant

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2020.00023

6,625 views
31 citations

Review

Published on 24 Jan 2020

Impedance Spectroscopy as a Tool for Monitoring Performance in 3D Models of Epithelial Tissues

in Tissue Engineering and Regenerative Medicine

Tatiana Gerasimenko
Sergey Nikulin
Galina Zakharova
Andrey Poloznikov
Vladimir Petrov
Ancha Baranova
Alexander Tonevitsky

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2019.00474

24,781 views
89 citations

Original Research

Published on 22 Jan 2020

Cryopreservation of Human iPS Cell Aggregates in a DMSO-Free Solution—An Optimization and Comparative Study

in Tissue Engineering and Regenerative Medicine

Rui Li
Kathlyn Hornberger
James R. Dutton
Allison Hubel

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2020.00001

20,096 views
296 citations

Review

Published on 10 Jan 2020

Organ-On-A-Chip in vitro Models of the Brain and the Blood-Brain Barrier and Their Value to Study the Microbiota-Gut-Brain Axis in Neurodegeneration

in Tissue Engineering and Regenerative Medicine

Ilaria Raimondi
Luca Izzo
Marta Tunesi
Manola Comar
Diego Albani
Carmen Giordano

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2019.00435

39,666 views
124 citations

Hypothesis and Theory

Published on 10 Jan 2020

Convergence of Scaffold-Guided Bone Reconstruction and Surgical Vascularization Strategies—A Quest for Regenerative Matching Axial Vascularization

in Tissue Engineering and Regenerative Medicine

David S. Sparks
Flavia Medeiros Savi
Siamak Saifzadeh
Michael A. Schuetz
Michael Wagels
Dietmar W. Hutmacher

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2019.00448

7,430 views
28 citations

Original Research

Published on 20 Dec 2019

Unraveling the Molecular Signature of Extracellular Vesicles From Endometrial-Derived Mesenchymal Stem Cells: Potential Modulatory Effects and Therapeutic Applications

in Tissue Engineering and Regenerative Medicine

Federica Marinaro
María Gómez-Serrano
Inmaculada Jorge
Juan Carlos Silla-Castro
Jesús Vázquez
Francisco Miguel Sánchez-Margallo
Rebeca Blázquez
Esther López
Verónica Álvarez
Javier G. Casado

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2019.00431

12,618 views
51 citations

Original Research

Published on 17 Dec 2019

The Influence of Pro-Inflammatory Factors on Sclerostin and Dickkopf-1 Production in Human Dental Pulp Cells Under Hypoxic Conditions

in Tissue Engineering and Regenerative Medicine

Klara Janjić
Mohammad Samiei
Andreas Moritz
Hermann Agis

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2019.00430

3,201 views
3 citations

Review

Published on 13 Dec 2019

Bioengineered Platforms for Chronic Wound Infection Studies: How Can We Make Them More Human-Relevant?

in Tissue Engineering and Regenerative Medicine

Snehal Kadam
Shivani Nadkarni
Janhavi Lele
Savani Sakhalkar
Pratiksha Mokashi
Karishma Surendra Kaushik

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2019.00418

15,062 views
52 citations

Original Research

Published on 13 Dec 2019

Biophysical Control of Bile Duct Epithelial Morphogenesis in Natural and Synthetic Scaffolds

in Tissue Engineering and Regenerative Medicine

Anette Funfak
Latifa Bouzhir
Emilie Gontran
Nicolas Minier
Pascale Dupuis-Williams
Samy Gobaa

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2019.00417

7,536 views
28 citations

Original Research

Published on 12 Dec 2019

Human Osteoblast Migration in DC Electrical Fields Depends on Store Operated Ca2+-Release and Is Correlated to Upregulation of Stretch-Activated TRPM7 Channels

in Tissue Engineering and Regenerative Medicine

Marco Rohde
Josefin Ziebart
Timo Kirschstein
Tina Sellmann
Katrin Porath
Friederike Kühl
Bachir Delenda
Christian Bahls
Ursula van Rienen
Rainer Bader

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2019.00422

6,827 views
24 citations

Correction

Published on 06 Dec 2019

Corrigendum: Osteoblast-Derived Vesicle Protein Content Is Temporally Regulated During Osteogenesis: Implications for Regenerative Therapies

in Tissue Engineering and Regenerative Medicine

Owen G. Davies
Sophie C. Cox
Ioannis Azoidis
Adam J. A. McGuinness
Megan Cooke
Liam M. Heaney
Edward T. Davis
Simon W. Jones
Liam M. Grover

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2019.00392

2,414 views
4 citations

Review

Published on 27 Nov 2019

Mesenchymal Stromal Cell-Based Bone Regeneration Therapies: From Cell Transplantation and Tissue Engineering to Therapeutic Secretomes and Extracellular Vesicles

in Tissue Engineering and Regenerative Medicine

Darja Marolt Presen
Andreas Traweger
Mario Gimona
Heinz Redl

Frontiers in Bioengineering and Biotechnology

doi 10.3389/fbioe.2019.00352

16,528 views
128 citations

1,154 articles

articles

Five Decades Later, Are Mesenchymal Stem Cells Still Relevant?

Thermal Bioprinting Causes Ample Alterations of Expression of LUCAT1, IL6, CCL26, and NRN1L Genes and Massive Phosphorylation of Critical Oncogenic Drug Resistance Pathways in Breast Cancer Cells

Two-Dimensional Cellular and Three-Dimensional Bio-Printed Skin Models to Screen Topical-Use Compounds for Irritation Potential

Auto Micro Atomization Delivery of Human Epidermal Organoids Improves Therapeutic Effects for Skin Wound Healing

Lung Microvascular Niche, Repair, and Engineering

Multiparametric Optical Bioimaging Reveals the Fate of Epoxy Crosslinked Biomeshes in the Mouse Subcutaneous Implantation Model

In situ Enabling Approaches for Tissue Regeneration: Current Challenges and New Developments

Electrospun Polymers in Cartilage Engineering—State of Play

The Secretome Derived From Mesenchymal Stromal Cells Cultured in a Xeno-Free Medium Promotes Human Cartilage Recovery in vitro

Influence of the Fabrication Accuracy of Hot-Embossed PCL Scaffolds on Cell Growths

Corrigendum: Bioengineered Platforms for Chronic Wound Infection Studies: How Can We Make Them More Human-Relevant?

Optogenetics: Background, Methodological Advances and Potential Applications for Cardiovascular Research and Medicine

A Self-Setting Hydrogel of Silylated Chitosan and Cellulose for the Repair of Osteochondral Defects: From in vitro Characterization to Preclinical Evaluation in Dogs

Impedance Spectroscopy as a Tool for Monitoring Performance in 3D Models of Epithelial Tissues

Cryopreservation of Human iPS Cell Aggregates in a DMSO-Free Solution—An Optimization and Comparative Study

Organ-On-A-Chip in vitro Models of the Brain and the Blood-Brain Barrier and Their Value to Study the Microbiota-Gut-Brain Axis in Neurodegeneration

Convergence of Scaffold-Guided Bone Reconstruction and Surgical Vascularization Strategies—A Quest for Regenerative Matching Axial Vascularization

Unraveling the Molecular Signature of Extracellular Vesicles From Endometrial-Derived Mesenchymal Stem Cells: Potential Modulatory Effects and Therapeutic Applications

The Influence of Pro-Inflammatory Factors on Sclerostin and Dickkopf-1 Production in Human Dental Pulp Cells Under Hypoxic Conditions

Bioengineered Platforms for Chronic Wound Infection Studies: How Can We Make Them More Human-Relevant?

Biophysical Control of Bile Duct Epithelial Morphogenesis in Natural and Synthetic Scaffolds

Human Osteoblast Migration in DC Electrical Fields Depends on Store Operated Ca2+-Release and Is Correlated to Upregulation of Stretch-Activated TRPM7 Channels

Corrigendum: Osteoblast-Derived Vesicle Protein Content Is Temporally Regulated During Osteogenesis: Implications for Regenerative Therapies

Mesenchymal Stromal Cell-Based Bone Regeneration Therapies: From Cell Transplantation and Tissue Engineering to Therapeutic Secretomes and Extracellular Vesicles